Brincidofovir Effectively Inhibits Proliferation of Pseudorabies Virus by Disrupting Viral Replication by Huihui Guo, Qingyun Liu, Dan Yang, Hao Zhang, Yan Kuang, Yafei Li, Huanchun Chen, Xiangru Wang

Subjects: Get full text

TREATMENT OF HEPATITIS C WITHOUT INTERFERON IN PATIENTS UNDERGOING LIVER TRANSPLANTATION by M. Sh. Khubutia, V. E. Syutkin

Subjects: Get full text

HepFREEPak: protocol for a multi-centre, prospective observational study examining efficacy and impact of current therapies for the treatment of hepatitis C in Pakistan and reporting resistance to antiviral drugs: study protocol by Ambreen Arif, Aliya Hasnain, Auj Chaudhry, Muhammad Asim, Muhammad Nabeel Shafqat, Abeer Altaf, Noor Saba, Polychronis Kemos, M. Azim Ansari, Eleanor Barnes, Chris Metcalfe, Peter Vickerman, Huma Qureshi, Saeed Hamid, Asad Ali Choudhry, Saad Khalid Niaz, Graham R. Foster, Naheed Choudhry

Get full text

Trends, variation, and clinical characteristics of recipients of antiviral drugs and neutralising monoclonal antibodies for covid-19 in community settings: retrospective, descriptive cohort study of 23.4 million people in OpenSAFELY by Green, ACA, Curtis, HJ, Higgins, R, Nab, L, Mahalingasivam, V, Smith, RM, Mehrkar, A, Inglesby, P, Drysdale, H, DeVito, NJ, Croker, R, Rentsch, CT, Bhaskaran, K, Tazare, J, Zheng, B, Andrews, CD, Bacon, SCJ, Davy, S, Dillingham, I, Evans, D, Fisher, L, Hickman, G, Hopcroft, LEM, Hulme, WJ, Massey, J, MacDonald, O, Morley, J, Morton, CE, Park, RY, Walker, AJ, Ward, T, Wiedemann, M, Bates, C, Cockburn, J, Parry, J, Hester, F, Harper, S, Douglas, IJ, Evans, SJW, Goldacre, B, Tomlinson, LA, MacKenna, B

“…<p><strong>Objective:</strong> To ascertain patient eligibility status and describe coverage of antiviral drugs and neutralising monoclonal antibodies (nMAB) as treatment for covid-19 in community settings in England.…”

Screening and verification of antiviral compounds against HSV-1 using a method based on a plaque inhibition assay by Yingxian Yin, Jiahui Li, Ling Su, Zhiying Ou, Qingqun Lv, Misi Xiao, Changbing Wang, Dan Zeng, Yiling Gu, Fengxia Yang, Minxia Chen, Shaojuan Feng, Wanming Hu, Fengling Bu, Bing Zhu, Yi Xu

Subjects: “…Antiviral drug screening…”
Get full text

A Fungal Defensin Targets the SARS−CoV−2 Spike Receptor−Binding Domain by Bin Gao, Shunyi Zhu

Subjects: Get full text

Aptamer-Mediated Antiviral Approaches for SARS-CoV-2 by Kei Xian Tan, Jaison Jeevanandam, João Rodrigues, Michael K. Danquah

Subjects: Get full text

Treatment Trends of Myocarditis with Coxsackievirus B3 infection by Dalya Basil Hanna, Ghaith Ali Jasim, Arwa Mujahid Abdullah Al-Shuwaikh

Subjects: “…Viral Myocarditis, Coxsackievirus B3, Ribosomal nucleic acid, Antiviral drug.…”
Get full text

Picornavirus 2C proteins: structure-function relationships and interactions with host factors by Chunhui Yin, Chunhui Yin, Chunhui Yin, Haomiao Zhao, Haomiao Zhao, Haomiao Zhao, Xiaoyi Xia, Xiaoyi Xia, Zhengyang Pan, Zhengyang Pan, Daoqun Li, Daoqun Li, Leiliang Zhang, Leiliang Zhang, Leiliang Zhang

Subjects: Get full text

Animal Models for Influenza Virus Pathogenesis and Transmission by Anice C. Lowen, Nicole M. Bouvier

Subjects: Get full text

Dibromopinocembrin and Dibromopinostrobin Are Potential Anti-Dengue Leads with Mild Animal Toxicity by Siwaporn Boonyasuppayakorn, Thanaphon Saelee, Peerapat Visitchanakun, Asada Leelahavanichkul, Kowit Hengphasatporn, Yasuteru Shigeta, Thao Nguyen Thanh Huynh, Justin Jang Hann Chu, Thanyada Rungrotmongkol, Warinthorn Chavasiri

Subjects: Get full text

Targeting Viral Ion Channels: A Promising Strategy to Curb SARS-CoV-2 by Anamika Singh, Isaiah T. Arkin

Subjects: Get full text

Identification of Potential Drug Targets of Broad-Spectrum Inhibitors with a Michael Acceptor Moiety Using Shotgun Proteomics by Hao-Wei Chu, Bidyadhar Sethy, Pei-Wen Hsieh, Jim-Tong Horng

Subjects: “…antiviral drug…”
Get full text

Potential therapeutic drug candidates against SARS-CoV-2 (COVID‐19) through molecular docking: A review by Aynaz Nourani, Vahid Rahimkhoei, Ali Akbari

Subjects: “…antiviral drug…”
Get full text

Insights into structural, vibrational, and chemical shift characteristics, solvents impact (polar and nonpolar) on electronic properties and reactive sites, ADMET predictions, and ligand-protein interactions for antiviral drugs safrole and isosafrole: An in-silico approach by A. Ram Kumar, S. Selvaraj, P. Rajkumar, J. Dhanalakshmi, Mohanraj Kumar, Senthil Kumar Nagarajan, P. Jayaprakash, G.P. Sheeja Mol, Shikha Awasthi, Sarvesh Kumar Pandey

Get full text

The deleterious effects of sofosbuvir and ribavirin (antiviral drugs against hepatitis C virus) on different body systems in male albino rats regarding reproductive, hematological, biochemical, hepatic, and renal profiles and histopathological changes by Rana A. Ali, Eatemad A. Awadalla, Yahia A. Amin, Samer S. Fouad, Maha Abd-El Baki Ahmed, Mohammed H. Hassan, Emaad Abdel-Kahaar, Rehab H. Abdel-Aziz

“…This study pertains to a comprehensive assessment of the deleterious effects of sofosbuvir (an antiviral drug against chronic HCV) or sofosbuvir combined with ribavirin (an antiviral drug against RNA and DNA viruses) on several biological activities of the body, including hematological, hormonal, biochemical, histological, and immunohistochemical examinations during a long-standing period on male healthy rats. …”
Get full text

In Vivo Antiviral Activity of Baloxavir against PA/I38T-Substituted Influenza A Viruses at Clinically Relevant Doses by Takayuki Kuroda, Keita Fukao, Shinpei Yoshida, Ryoko Oka, Kaoru Baba, Yoshinori Ando, Keiichi Taniguchi, Takeshi Noshi, Takao Shishido

Subjects: Get full text

A Dual Pharmacological Strategy against COVID-19: The Therapeutic Potential of Metformin and Atorvastatin by Luis Adrián De Jesús-González, Rosa María del Ángel, Selvin Noé Palacios-Rápalo, Carlos Daniel Cordero-Rivera, Adrián Rodríguez-Carlos, Juan Valentin Trujillo-Paez, Carlos Noe Farfan-Morales, Juan Fidel Osuna-Ramos, José Manuel Reyes-Ruiz, Bruno Rivas-Santiago, Moisés León-Juárez, Ana Cristina García-Herrera, Adriana Clara Ramos-Cortes, Erika Alejandra López-Gándara, Estefanía Martínez-Rodríguez

Subjects: Get full text

Acute respiratory infections of concomitant etiology in children by S. V. Nikolaeva, Yu. N. Khlypovka, A. V. Gorelov

Subjects: Get full text

Blockers of the SARS-CoV-2 3a Channel Identified by Targeted Drug Repurposing by Prabhat Pratap Singh Tomar, Miriam Krugliak, Isaiah T. Arkin

Subjects: Get full text