Phosphatidylinositol 4,5-Bisphosphate Is an HCV NS5A Ligand and Mediates Replication of the Viral Genome by Cho, Nam-Joon, Lee, Choongho, Pang, Phillip S., Pham, Edward A., Fram, Benjamin, Nguyen, Khanh, Xiong, Anming, Sklan, Ella H., Elazar, Menashe, Koytak, Elif S., Kersten, Caroline, Kanazawa, Kay K., Frank, Curtis W., Glenn, Jeffrey S.

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Protein Folding, Host Cell Proteostasis, and Viral Evolution by Yoon, Jimin

“…A major challenge associated with developing effective antiviral strategies is the exceptionally high mutation rate of RNA viruses, which endows them with a remarkable capacity to adapt to selection pressures such as antibodies or antiviral drugs. …”
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