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Comparative Genomics Reveals Novel Species and Insights into the Biotechnological Potential, Virulence, and Resistance of <i>Alcaligenes</i>
Published 2023-09-01“…Pan-GWAS analysis uncovered 389 species-associated genes, including cold shock proteins (e.g., <i>csp</i>A) and aquaporins (e.g., <i>aqp</i>Z) found exclusively in the water-isolated species, <i>Alcaligenes aquatilis</i>. …”
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2562
Candidate Genes for Salt Tolerance in Forage Sorghum under Saline Conditions from Germination to Harvest Maturity
Published 2023-01-01“…Shoot water and carbon partitioning, for example, are dominated by genes from the aquaporins and SWEET families, respectively. The gibberellin (GA) family of genes is prevalent during pre-saline exposure seed dormancy breaking and early embryo development at post-saline exposure. …”
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2563
Specialized Pro-resolving Mediators Regulate Alveolar Fluid Clearance during Acute Respiratory Distress Syndrome
Published 2018-01-01“…Results: Specialized pro-resolving mediators (SPMs), as the proinflammatory mediators, not only upregulated epithelial sodium channel, Na,K-ATPase, cystic fibrosis transmembrane conductance regulator (CFTR), and aquaporins levels, but also improved Na,K-ATPase activity to promote AFC in ARDS. …”
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2564
Ion channels in dry eye disease
Published 2023-01-01“…Hence, alterations in the expression and/or activity of about 33 types of ion channels that belong to voltage-gated channels, ligand-gated channels, mechanosensitive ion channel, aquaporins, chloride ion channel, sodium–potassium–chloride pumps or cotransporters have been investigated in the context of ocular surface health and DED in animal and/or human subjects. …”
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2565
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2566
Increased expression of AQP 1 and AQP 5 in rat lungs ventilated with low tidal volume is time dependent.
Published 2014-01-01“…BACKGROUND AND GOALS: Mechanical ventilation (MV) can induce or worsen pulmonary oedema. Aquaporins (AQPs) facilitate the selective and rapid bi-directional movement of water. …”
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2567
Cold Atmospheric Plasma and Plasma-Activated Medium Trigger RONS-Based Tumor Cell Apoptosis
Published 2019-10-01“…At the site of inactivated catalase, cell-generated H2O2 enters the cell via aquaporins, depletes glutathione and thus abrogates the cell’s protection towards lipid peroxidation. …”
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2568
Enteropathogenic Escherichia coli remodels host endosomes to promote endocytic turnover and breakdown of surface polarity.
Published 2019-06-01“…Protein cargoes, e.g. transferrin receptors, β1 integrins and aquaporins, which exploit the endocytic pathways mediated by these machineries, were also found to be recruited to these sites. …”
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2569
Human AQP5 plays a role in the progression of chronic myelogenous leukemia (CML).
Published 2008-07-01“…Aquaporins (AQPs) have previously been associated with increased expression in solid tumors. …”
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2570
Algal polysaccharides–Selenium nanoparticles regulate the uptake and distribution of selenium in rice plants
Published 2023-03-01“…The root uptake of APS-SeNPs was inhibited by AgNO3 (64.81%–79.09%) and carbonyl cyanide 3-chlorophenylhydrazone (CCCP; 19.83%–29.03%), indicating that the uptake of APS-SeNPs by rice roots is mainly via aquaporins and is also affected by metabolic activity. …”
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2571
Heterogeneous root zone salinity mitigates salt injury to Sorghum bicolor (L.) Moench in a split-root system.
Published 2019-01-01“…Similarly, the expression of the majority of aquaporins and essential mineral transporters was upregulated in the NaCl-free root side in the nonuniform salinity treatment, whereas abscisic acid (ABA)-related and salt stress-responsive TF transcripts were more abundant in the high-saline root side in the nonuniform salinity treatment. …”
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2572
Intestinal Fluid Permeability in Atlantic Salmon (Salmo salar L.) Is Affected by Dietary Protein Source.
Published 2016-01-01“…Altered DI expression of a battery of genes encoding aquaporins, ion transporters, tight junction and adherens junction proteins suggested reduced transcellular transport of water as well as a tightening of the junction barrier in fish fed the SBMWG diet, which may explain the observed higher fecal water content and plasma osmolality. …”
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2573
Algal MIPs, high diversity and conserved motifs
Published 2011-04-01“…<p>Abstract</p> <p>Background</p> <p>Major intrinsic proteins (MIPs) also named aquaporins form channels facilitating the passive transport of water and other small polar molecules across membranes. …”
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2574
Osmotic gradients and transretinal water flow—a quantitative elemental microanalytical study of frozen hydrated chick eyes
Published 2022-10-01“…As expected, the greatest difference in resultant osmotic concentration gradients, [calculated using the combined concentrations of sodium (Na) and potassium (K)] and tissue hydration [oxygen-defined water concentration], occurs in the outer retina and, in particular, in the RPE where the apical and basal membranes are characterized by numerous bioenergetically active, osmoregulating ion transport mechanisms, aquaporins, and chloride (Cl) channels. Our results also demonstrate that the high intracellular Na+ and K+ concentrations in the apical region of the RPE are partially derived from the melanosomes. …”
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2575
Osmolarity-regulated swelling initiates egg activation in Drosophila
Published 2021-08-01“…We show that the swelling process is regulated by the conserved osmoregulatory channels, aquaporins and DEGenerin/Epithelial Na+ channels. Furthermore, through pharmacological and genetic disruption, we reveal a concentration-dependent requirement of transient receptor potential M channels to transport calcium, most probably from the perivitelline space, across the plasma membrane into the mature oocyte. …”
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2576
Halophytes: Potential Resources for Salt Stress Tolerance Genes and Promoters
Published 2017-05-01“…Several known genes like antiporters (NHX, SOS, HKT, VTPase), ion channels (Cl−, Ca2+, aquaporins), antioxidant encoding genes (APX, CAT, GST, BADH, SOD) and some novel genes such as USP, SDR1, SRP etc. were isolated from halophytes and explored for developing stress tolerance in the crop plants (glycophytes). …”
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2577
Cerebrospinal fluid dynamics and intracranial pressure elevation in neurological diseases
Published 2019-04-01“…Emerging evidence suggests that pharmacological targeting of aquaporins, transient receptor potential vanilloid type 4 (TRPV4), and the Na+–K+–2Cl− cotransporter (NKCC1) merit further investigation as potential targets in neurological diseases involving impaired brain fluid dynamics and elevated ICP.…”
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2578
Transcriptomic and co-expression network analyses on diverse wheat landraces identifies candidate master regulators of the response to early drought
Published 2023-06-01“…But as the timing of periods of drought stress become increasingly unpredictable, a more complete understanding of the response to drought during early development is also needed.MethodsHere, we utilized the YoGI landrace panel to identify 10,199 genes which were differentially expressed under early drought stress, before weighted gene co-expression network analysis (WGCNA) was used to construct a co-expression network and identify hub genes in modules particularly associated with the early drought response.ResultsOf these hub genes, two stood out as novel candidate master regulators of the early drought response – one as an activator (TaDHN4-D1; TraesCS5D02G379200) and the other as a repressor (uncharacterised gene; TraesCS3D02G361500).DiscussionAs well as appearing to coordinate the transcriptional early drought response, we propose that these hub genes may be able to regulate the physiological early drought response due to potential control over the expression of members of gene families well-known for their involvement in the drought response in many plant species, namely dehydrins and aquaporins, as well as other genes seemingly involved in key processes such as, stomatal opening, stomatal closing, stomatal morphogenesis and stress hormone signalling.…”
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2579
Osmosensitivity of transient receptor potential vanilloid 1 is synergistically enhanced by distinct activating stimuli such as temperature and protons.
Published 2011-01-01“…Of note, HgCl(2), which blocks aquaporins and inhibits cell-volume changes, significantly reduced the osmosensitive response. …”
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2580
Soil Water Deficit Reduced Root Hydraulic Conductivity of Common Reed (<i>Phragmites australis</i>)
Published 2023-10-01“…A decrease in soil moisture content significantly influenced root morphological and anatomical characteristics, which, in turn, altered <i>Lp<sub>r</sub></i>, and the transcriptome results suggest that this may be associated with the variation in the expression of abscisic acid (ABA) and aquaporins (AQPs) genes. Our initial findings address a gap in our understanding of reed hydraulics, offering fresh theoretical insights into how herbaceous plants respond to external stressors.…”
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