Comparison of inebilizumab or rituximab in addition to glucocorticoid therapy for neuromyelitis optica spectrum disorders by Chu-Yuan Lou, Yong Wang, Jia-Yuan Xing, Teng Ma, Lei Tao, Xiao-Tang Wang, Run-Sheng Wang

“…Subsequently, Group INB received inebilizumab injections during the remission phase, while Group RTX received rituximab injections. A comparison of aquaporins 4 (AQP4) titer values, peripheral blood B lymphocyte counts, and visual function recovery was conducted before and 8wk after treatment. …”
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Pingwei San Ameliorates Spleen Deficiency-Induced Diarrhea through Intestinal Barrier Protection and Gut Microbiota Modulation by Yimeng Fan, Qingyu Zhao, Yuanyuan Wei, Huiru Wang, Yu Ga, Yannan Zhang, Zhihui Hao

“…Additionally, quantitative polymerase chain reaction (qPCR) and immunohistochemistry were employed to assess the expression of inflammatory factors, aquaporins (AQPs), and tight junction markers in the colon tissues. …”
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On the necessity of dissecting sequence similarity scores into segment-specific contributions for inferring protein homology, function prediction and annotation by Wong, Wing-Cheong, Maurer-Stroh, Sebastian, Eisenhaber, Birgit, Eisenhaber, Frank

“…Conclusions Sequence similarity core dissection with regard to fold-critical and other contributions systematically suppresses false hits and, additionally, recovers previously obscured homology relationships such as the one between aquaporins and formate/nitrite transporters that, so far, was only supported by structure comparison.…”
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The coming of age of water channels for separation membranes: from biological to biomimetic to synthetic by Lim, Yu Jie, Goh, Kunli, Wang, Rong

“…Herein, this review outlines the progress of a comprehensive amount of nanochannels, which include aquaporins, pillar[5]arenes, I-quartets, different types of nanotubes and their porins, graphene-based materials, metal- and covalent-organic frameworks, porous organic cages, MoS2, and MXenes, offering a comparative glimpse into where their potential lies. …”
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Bicarbonate-Dependent Detoxification by Mitigating Ammonium-Induced Hypoxic Stress in <i>Triticum aestivum</i> Root by Xiao Liu, Yunxiu Zhang, Chengming Tang, Huawei Li, Haiyong Xia, Shoujin Fan, Lingan Kong

“…Transcriptomic analysis revealed that compared to CK, SA treatment at 48 h significantly upregulated the expression of genes encoding fermentation enzymes (pyruvate decarboxylase (PDC), alcohol dehydrogenase (ADH), and lactate dehydrogenase (LDH)) and oxygen consumption enzymes (respiratory burst oxidase homologs, dioxygenases, and alternative oxidases), downregulated the expression of genes encoding oxygen transporters (PIP-type aquaporins, non-symbiotic hemoglobins), and those involved in energy metabolism, including tricarboxylic acid (TCA) cycle enzymes and ATP synthases, but upregulated the glycolytic enzymes in the roots and downregulated the expression of genes involved in the cell cycle and elongation. …”
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AtZAT10/STZ1 improves drought tolerance and increases fiber yield in cotton by Lixia Qin, Hehe He, Liqun Yang, Huanyang Zhang, Jing Li, Yonghong Zhu, Jianguo Xu, Gaili Jiao, Chengbin Xiang, Chuangyun Wang, Shenjie Wu

“…Transcriptome profiling unveils 106 differentially expressed genes in transgenic cotton leaves post-drought treatment, including protein kinases, transcription factors, aquaporins, and heat shock proteins, indicative of an orchestrated stress response. …”
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Elucidating the roles of SOD3 correlated genes and reactive oxygen species in rare human diseases using a bioinformatic-ontology approach. by Mark Stanworth, Shu-Dong Zhang

“…Both Reactive Oxygen Species diffuse through aquaporins causing oxidative stress and biomolecular damage. …”
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In-silico Exploration of Channel Type and Efflux Silicon Transporters and Silicification Proteins in 80 Sequenced Viridiplantae Genomes by Muhammad Amjad Nawaz, Farrukh Azeem, Alexander Mikhailovich Zakharenko, Xiao Lin, Rana Muhammad Atif, Faheem Shehzad Baloch, Ting-Fung Chan, Gyuhwa Chung, Junghee Ham, Sangmi Sun, Kirill S. Golokhvast

“…It is transported and distributed within the plant body through a cooperative system of channel type (e.g., <i>OsLsi1</i>) and efflux (Lsi2s e.g., <i>OsLsi2</i>) Si transporters (SITs) that belong to Noduline-26 like intrinsic protein family of aquaporins and an uncharacterized anion transporter family, respectively. …”
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Glutamine in suppression of lipopolysaccharide-induced piglet intestinal inflammation: The crosstalk between AMPK activation and mitochondrial function by Liuqin He, Xihong Zhou, Ziping Wu, Yanzhong Feng, Di Liu, Tiejun Li, Yulong Yin

“…Our current results showed that compared with the LPS treatment, the Gln + LPS treatment had better growth performance and greater villus height (P < 0.05), and the Gln + LPS treatment reduced the rate of diarrhea by 6.4% (P < 0.05); the Gln + LPS treatment decreased serum tumor necrosis factor (TNF-ɑ), interleukin-6 (IL-6), K+, cortisol and insulin levels, whereas increased (P < 0.05) serum immunoglobulin M and epidermal growth factor levels; the Gln + LPS treatment increased (P < 0.05) the expression of aquaporins and AMPK pathway-associated targets in the jejunum and ileum of piglets, whereas decreased the expression of ion transporters (P < 0.05). …”
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Study on the physiological responses and tolerance mechanisms to subchronic carbonate alkalinity exposure in the gills of Paramisgurnus dabryanus by Luojia Li, Wei Luo, Pengyu Chen, Yujun Wang, Dan Liu, Yuzhou Lan, Xialin Chen, Lechan Zhou, Shiyong Yang, Zongjun Du

“…A total of 3718 differentially expressed genes (DEGs) and 205 differential metabolites (DMs) were identified between the control group and 30 mmol/L NaHCO3 group, involved in ion transport (Na+/K+-ATPase, V-type ATPase, carbonic anhydrase, and ABC transporters), ammonia transport (Rh glycoproteins and Aquaporins), amino acid metabolism, carbohydrate metabolism, and fatty acid metabolism. …”
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Effect of heat stress on the hypothalamic expression profile of water homeostasis‐associated genes in low‐ and high‐water efficient chicken lines by Loujain Aloui, Elizabeth S. Greene, Travis Tabler, Kentu Lassiter, Kevin Thompson, Walter G. Bottje, Sara Orlowski, Sami Dridi

“…At the molecular level, the overall hypothalamic expression of aquaporins (AQP8 and AQP12), arginine vasopressin (AVP) and its related receptor AVP2R, angiotensinogen (AGT), angiotensin II receptor type 1 (AT1), and calbindin 2 (CALB2) were significantly lower; however, CALB1 mRNA and AQP2 protein levels were higher in HWE compared to LWE line. …”
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Visual Function Improvement after Plasma Exchange Therapy for Acute Optic Neuritis in Neuromyelitis Optica Spectrum Disorders: Case Series and Review by Raluca Iancu, Ruxandra Pirvulescu, Nicoleta Anton, George Iancu, Sinziana Istrate, Mihaela Oana Romanitan, Aida Geamanu, Matei Popa Cherecheanu

“…Objective: Neuromyelitis optica (NMO) and neuromyelitis optica spectrum disorder (NMOSD) are autoimmune-mediated central nervous system disorders distinguished by the presence of serum aquaporine-4 IgG antibody (AQP4-Ab). The clinical panel comprises severe optic neuritis (ON) and transverse myelitis, which can result in incomplete recovery and a high risk of recurrence. …”
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Effect of dietary soybean saponin Bb on the growth performance, intestinal nutrient absorption, morphology, microbiota, and immune response in juvenile Chinese soft-shelled turtle... by Yue Wang, Xinyue Jia, Zixue Guo, Ling Li, Tianyu Liu, Peiyu Zhang, Peiyu Zhang, Haiyan Liu, Haiyan Liu

“…At the same time, the expressions of key transcription factors (STAT1, TBX21, FOS), chemokines (CCL3), cytokines (TNF-α, IL-8), and aquaporins (AQP3, AQP6) in the inflammatory response were increased by soybean saponin Bb in the large intestine of a turtle. …”
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Responses of transcriptome and metabolome in the roots of Pugionium cornutum (L.) Gaertn to exogenously applied phthalic acid by Xiaoyan Zhang, Kezhen Ning, Zhongren Yang, Xiumei Huang, Hongtao Yu, Nana Fu, Xinyuan Qin, Lizhen Hao, Fenglan Zhang

“…In addition, the L-histidinol content was highest under 0.1 mmol·L− 1 phthalic acid, and a total of eleven differentially expressed genes were significantly positively correlated with the L-histidinol content, all of which were annotated to heat shock proteins, aquaporins and cysteine proteases. Conclusions Accumulation of autotoxins altered the metabolic balance in P. cornutum (L.) …”
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Rumen-Degradable Starch Improves Rumen Fermentation, Function, and Growth Performance by Altering Bacteria and Its Metabolome in Sheep Fed Alfalfa Hay or Silage by Wenliang Guo, Meila Na, Shuwei Liu, Kenan Li, Haidong Du, Jing Zhang, Renhua Na

“…Increased RDS in the diet improved the daily matter intake, average daily gain, and rumen weight, reduced the F:G, and enhanced the rumen nitrogen capture rate by decreasing total amino acids and the NH₃-N concentration to increase BCP, aquaporins 3 gene, and protein expression. The rumen microbiota also changed as the HR diet reduced the Chao index (<i>p</i> < 0.05). …”
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Molecular physiology of Antarctic diatom natural assemblages and bloom event reveal insights into strategies contributing to their ecological success by Carly M. Moreno, Margaret Bernish, Meredith G. Meyer, Zuchuan Li, Nicole Waite, Natalie R. Cohen, Oscar Schofield, Adrian Marchetti

“…We observed strong molecular evidence for iron limitation in shelf and slope regions of the WAP, where diatoms in these regions employed iron-starvation induced proteins, a geranylgeranyl reductase, aquaporins, and urease, among other strategies, while limiting the use of iron-containing proteins. …”
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Adverse effect of assisted reproductive technology-related hyperoestrogensim on the secretion and absorption of uterine fluid in superovulating mice during the peri-implantation pe... by Xinru Xia, Yuan Zhang, Meng Cao, Xiang Yu, Li Gao, Lianju Qin, Wei Wu, Yugui Cui, Jiayin Liu

“…During the peri-implantation period, morphological changes in the mouse uterus and implantation sites and the localization and protein levels of oestrogen receptors ERα and ERβ, the tight junction factors CLDN3 and OCLN, the aquaporins AQP3, AQP4 and AQP8, and the sodium channel proteins SCNN1α, SCNN1β and SCNN1γ were observed. …”
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Dietary supplementation with 0.4% L-arginine between days 14 and 30 of gestation enhances NO and polyamine syntheses and water transport in porcine placentae by Cassandra M. Herring, Fuller W. Bazer, Gregory A. Johnson, Heewon Seo, Shengdi Hu, Mohammed Elmetwally, Wenliang He, Daniel B. Long, Guoyao Wu

“…Placentae were analyzed for syntheses of NO and polyamines, water and amino acid transport, concentrations of amino acid-related metabolites, and the expression of angiogenic factors and aquaporins (AQPs). Results Compared to the control group, Arg supplementation increased (P < 0.05) the number of viable fetuses by 1.9 per litter, the number and diameter of placental blood vessels (+ 25.9% and + 17.0% respectively), embryonic survival (+ 18.5%), total placental weight (+ 36.5%), the total weight of viable fetuses (+ 33.5%), fetal crown-to-rump length (+ 4.7%), and total allantoic and amniotic fluid volumes (+ 44.6% and + 75.5% respectively). …”
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