Exploring COVID-19 vaccine hesitancy and uptake in Nairobi’s urban informal settlements: an unsupervised machine learning analysis of a longitudinal prospective cohort study from 2... by Edwine Barasa, Timothy Abuya, Jessie Pinchoff, Karen Austrian, Nandita Rajshekhar, Daniel Mwanga, Eva Muluve, Faith Mbushi, Christopher B Boyer

“…Objectives To illustrate the utility of unsupervised machine learning compared with traditional methods of analysis by identifying archetypes within the population that may be more or less likely to get the COVID-19 vaccine.Design A longitudinal prospective cohort study (n=2009 households) with recurring phone surveys from 2020 to 2022 to assess COVID-19 knowledge, attitudes and practices. …”
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Applying Mendelian randomization to appraise causality in relationships between smoking, depression and inflammation by D. Galan, B. I. Perry, V. Warrier, C. C. Davidson, O. Stupart, D. Easton, G. M. Khandaker, G. K. Murray

“…We aimed to characterize the association between lifetime smoking and depression, as well as to assess the role that genetically-predicted C-reactive protein (CRP) level, (an archetypal generalized inflammatory marker) and/or IL-6 activity, as a potential explanation for this association. …”
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A QCT View of the Interplay between Hydrogen Bonds and Aromaticity in Small CHON Derivatives by Miguel Gallegos, Daniel Barrena-Espés, José Manuel Guevara-Vela, Tomás Rocha-Rinza, Ángel Martín Pendás

“…We used a collection of simple archetypal examples of aromatic, non-aromatic and antiaromatic moieties within organic molecules to examine the changes in <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mi>π</mi></semantics></math></inline-formula> delocalisation and aromaticity induced by the Aromaticity and Antiaromaticity Modulated Hydrogen Bonds (AMHB). …”
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Andesites and evolution of the continental crust: Perspectives from the Central Volcanic Zone of the Andes by Dale H. Burns, Shanaka L. de Silva

“…Named for the Andes, andesites (53%–63% SiO2) are the archetypal magma erupted at magmatic arcs. They have been established as the average composition of continental crust and as such are integral to the growth and evolution of the continental crust. …”
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Pervasive gene deregulation underlies adaptation and maladaptation in trimethoprim-resistant E. coli by Rhea Vinchhi, Chetna Yelpure, Manasvi Balachandran, Nishad Matange

“…ABSTRACTThe archetypal PhoQP two-component system from Enterobacteria regulates pathways like magnesium homeostasis in Escherichia coli and virulence factor expression in Salmonella enterica. …”
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Detecting Clinically Relevant Emotional Distress and Functional Impairment in Children and Adolescents: Protocol for an Automated Speech Analysis Algorithm Development Study by Yared Alemu, Hua Chen, Chenghao Duan, Desmond Caulley, Rosa I Arriaga, Emre Sezgin

“…MethodsInformed by theoretical foundations (the Theory of Psychological Trauma Biomarkers and Archetypal Voice Categories), we developed our methodology to focus on 5 emotions: anger, happiness, fear, neutral, and sadness. …”
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KULTŪRINIO IR SIMBOLINIO KAPITALO GAMYBA: "DISNEY" FENOMENAS by Gintautas Mažeikis

“…Disney relies on investigation of basic cultural habitus, archetypes and symbols of thinking. In this way, Disney creates the world of fantasy, dreams and Utopias. …”
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A mixed distribution approach for low-flow frequency analysis – Part 1: Concept, performance, and effect of seasonality by G. Laaha

“…The main strength of the model is that it allows the user to estimate return periods of summer low flows, winter low flows, and annual return periods in a theoretically sound and consistent way. Using archetypal examples, we show how the model behaves for a range of low-flow regimes, from distinct winter and summer regimes to mixed regimes where seasonal occurrence in summer and winter is equally likely. …”
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KULTŪRINIO IR SIMBOLINIO KAPITALO GAMYBA: "DISNEY" FENOMENAS by Gintautas Mažeikis

“…Disney relies on investigation of basic cultural habitus, archetypes and symbols of thinking. In this way, Disney creates the world of fantasy, dreams and Utopias. …”
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Building technological capability within satellite programs in developing countries by Wood, Danielle Renee

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Spinning off new ventures from research institutions outside high tech entrepreneurial areas by Degroof, Jean-Jacques

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Engineering carrier dynamics in lead halide perovskites by Lim, Swee Sien

“…This thesis reports on a series of studies using ultrafast optical spectroscopy on the archetypal bulk 3D perovskite, MAPI, to provide insights on the photophysics and recombination dynamics of this class of materials. …”
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The economics of cyber risk transfer by Woods, D

“…These cyber risk transfer products affect how risk managers make decisions. An archetypal example is insurers offering discounts on cyber insurance contingent on information security controls being in place. …”

Civil disobedience: a reasonable polemic by Muir, M

“…</p> <p>This fiftieth anniversary critique has two principal targets:</p> <p>First, the endemic idea of the praxis of civil disobedience itself, forged in the civil rights ferment of the US 1960s, and then carried over by successive generations of normative political theorist to the archetypal dissident concerns of subsequent decades. …”

Targeting the Ras superfamily via their regulatory GEF complexes by Gray, J

“…The modelling of a competitive inhibitor of a GEF/GTPase complex within this cycle supported the hypothesis that a GEF/GTPase inhibitor could slow the rate of nucleotide exchange in a manner not achieved by an archetypal competitive inhibitor which binds to the GTPase alone. …”

Spatial-economic characterization of resilient urban destinations by Lew, Shian Loong

“…Venice was chosen as an archetypical case for urban destination accessibility. …”
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Inhibition of Phosphodiesterase 4 by FCPR03 Alleviates Lipopolysaccharide-Induced Depressive-Like Behaviors in Mice: Involvement of p38 and JNK Signaling Pathways by Hui Yu, Zhengqiang Zou, Xiaolin Zhang, Wanli Peng, Chen Chen, Yicheng Ye, Jiangping Xu, Haitao Wang

“…Inhibition of phosphodiesterase 4 (PDE4) produces a robust anti-inflammatory effect in inflammatory cells. Unfortunately, archetypal PDE4 inhibitors cause intolerable gastrointestinal side-effects, such as vomiting and nausea. …”
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Heterozygous loss-of-function SMC3 variants are associated with variable growth and developmental features by Morad Ansari, Kamli N.W. Faour, Akiko Shimamura, Graeme Grimes, Emeline M. Kao, Erica R. Denhoff, Ana Blatnik, Daniel Ben-Isvy, Lily Wang, Benjamin M. Helm, Helen Firth, Amy M. Breman, Emilia K. Bijlsma, Aiko Iwata-Otsubo, Thomy J.L. de Ravel, Vincent Fusaro, Alan Fryer, Keith Nykamp, Lara G. Stühn, Tobias B. Haack, G. Christoph Korenke, Panayiotis Constantinou, Kinga M. Bujakowska, Karen J. Low, Emily Place, Jennifer Humberson, Melanie P. Napier, Jessica Hoffman, Jane Juusola, Matthew A. Deardorff, Wanqing Shao, Shira Rockowitz, Ian Krantz, Maninder Kaur, Sarah Raible, Victoria Dortenzio, Sabine Kliesch, Moriel Singer-Berk, Emily Groopman, Stephanie DiTroia, Sonia Ballal, Siddharth Srivastava, Kathrin Rothfelder, Saskia Biskup, Jessica Rzasa, Jennifer Kerkhof, Haley McConkey, Bekim Sadikovic, Sarah Hilton, Siddharth Banka, Frank Tüttelmann, Donald F. Conrad, Anne O’Donnell-Luria, Michael E. Talkowski, David R. FitzPatrick, Philip M. Boone

“…Here, we show that SMC3 behaves as an archetypal haploinsufficient gene: it is highly constrained against pLoF variants, strongly depleted for missense variants, and pLoF variants are associated with a range of developmental phenotypes. …”
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Cystic Fibrosis Patients Infected With Epidemic Pseudomonas aeruginosa Strains Have Unique Microbial Communities by Nicole Acosta, Barbara Waddell, Alya Heirali, Ranjani Somayaji, Ranjani Somayaji, Michael G. Surette, Michael G. Surette, Matthew L. Workentine, Harvey R. Rabin, Harvey R. Rabin, Michael D. Parkins, Michael D. Parkins

“…Pseudomonas aeruginosa is the archetypal cystic fibrosis (CF) pathogen. However, the clinical course experienced by infected individuals varies markedly. …”
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CAR requires Gadd45β to promote phenobarbital-induced mouse liver tumors in early stage by Takeshi Hori, Takeshi Hori, Kosuke Yokobori, Rick Moore, Masahiko Negishi, Tatsuya Sueyoshi

“…Phenobarbital (PB) is an archetypal substance used as a mouse hepatocellular carcinoma (HCC) promotor in established experimental protocols. …”
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