Toxic brainstem encephalopathy after artemisinin treatment for breast cancer. by White, N, Ashley, E, Nosten, F

A molecular marker of artemisinin-resistant Plasmodium falciparum malaria by Ariey, F, Witkowski, B, Amaratunga, C, Beghain, J, Langlois, A, Khim, N, Kim, S, Duru, V, Bouchier, C, Ma, L, Lim, P, Leang, R, Duong, S, Sreng, S, Suon, S, Chuor, C, Bout, D, Ménard, S, Rogers, W, Genton, B, Fandeur, T, Miotto, O, Ringwald, P, Le Bras, J, Berry, A

“…Plasmodium falciparum resistance to artemisinin derivatives in southeast Asia threatens malaria control and elimination activities worldwide. …”

HERITABILITY OF PARASITE CLEARANCE TIME FOLLOWING ARTEMISININ COMBINATION THERAPY by Anderson, T, Nair, S, Price, R, Barends, M, Jaidee, A, Nosten, F

Insights into Heterologous Biosynthesis of Arteannuin B and Artemisinin in Physcomitrella patens by Ikram, Nur Kusaira Khairul, Kashkooli, Arman Beyraghdar, Peramuna, Anantha, Krol, Alexander R. van der, Bouwmeester, Harro, Simonsen, Henrik Toft

“…Here, the full biosynthetic pathway of artemisinin, originating from Artemisia annua, was integrated into the moss Physcomitrella patens. …”

The effect of artemisinin on the pH of plasmodium falciparum digestive vacuole by Ibrahim, Nadiah

“…Artemisinin, a highly potent antimalarial drug is widely used due to the rapid killing of Plasmodium parasites. …”
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(−)-6-epi-Artemisinin, a Natural Stereoisomer of (+)-Artemisinin in the Opposite Enantiomeric Series, from the Endemic Madagascar Plant <i>Saldinia proboscidea</i>, an Atypical Source by Saholinirina Randrianarivo, Claudine Rasolohery, Sitraka Rafanomezantsoa, Heriniaina Randriamampionona, Liti Haramaty, Roger Marie Rafanomezantsoa, Eric H. Andrianasolo

“…Chemical and biological investigation of the Madagascar endemic plant <i>Saldinia proboscidea</i> led to the isolation of an isomer of artemisinin, (−)-6-epi-artemisinin (<b>2</b>). Its structure was elucidated using a combination of NMR and mass spectrometry. …”
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Pregnancy outcomes after first-trimester treatment with artemisinin derivatives versus non-artemisinin antimalarials: a systematic review and individual patient data meta-analysis by Saito, M, McGready, R, Tinto, H, Rouamba, T, Mosha, D, Rulisa, S, Kariuki, S, Desai, M, Manyando, C, Njunju, EM, Sevene, E, Vala, A, Augusto, O, Clerk, C, Were, E, Mrema, S, Kisinza, W, Byamugisha, J, Kagawa, M, Singlovic, J, Yore, M, van Eijk, AM, Mehta, U, Stergachis, A, Hill, J, Stepniewska, K, Gomes, M, Guérin, PJ, Nosten, F, Ter Kuile, FO, Dellicour, S

“…<strong>Background<br></strong> Malaria in the first trimester of pregnancy is associated with adverse pregnancy outcomes. Artemisinin-based combination therapies (ACTs) are a highly effective, first-line treatment for uncomplicated Plasmodium falciparum malaria, except in the first trimester of pregnancy, when quinine with clindamycin is recommended due to concerns about the potential embryotoxicity of artemisinins. …”

Triple artemisinin-based combination therapies versus artemisinin-based combination therapies for uncomplicated Plasmodium falciparum malaria: a multicentre, open-label, randomised clinical trial by Miotto, O, van der Pluijm, RW, Tripura, R, Hoglund, RM, Phyo, AP, Lek, D, ul Islam, A, Anvikar, AR, Satpathi, P, Satpathi, S, Behera, PK, Tripura, A, Baidya, S, Onyamboko, M, Chau, NH, Sovann, Y, Suon, S, Sreng, S, Mao, S, Oun, S, Yen, S, Amaratunga, C, Chutasmit, K, Saelow, C, Runcharern, R, Kaewmok, W, Hoa, NY, Thanh, NV, Hanboonkunupakarn, B, Callery, JJ, Mohanty, AK, Heaton, J, Thant, M, Gantait, K, Ghosh, T, Amato, R, Pearson, RD, Jacob, CG, Gonçalves, S, Mukaka, M, Waithira, N, Woodrow, CJ, Grobusch, MP, van Vugt, M, Fairhurst, RM, Cheah, PY, Peto, TJ, von Seidlein, L, Dhorda, M, Maude, RJ

“…<br><strong>Background: </strong>Artemisinin and partner-drug resistance in Plasmodium falciparum are major threats to malaria control and elimination. …”

Effect of silver nanoparticle size on interaction with artemisinin: First principle study by Mahmood Akbari, Razieh Morad, Malik Maaza

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Preventing antimalarial drug resistance with triple artemisinin-based combination therapies by Tran Dang Nguyen, Bo Gao, Chanaki Amaratunga, Mehul Dhorda, Thu Nguyen-Anh Tran, Nicholas J. White, Arjen M. Dondorp, Maciej F. Boni, Ricardo Aguas

“…Abstract Increasing levels of artemisinin and partner drug resistance threaten malaria control and elimination globally. …”
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Safety of Artemisinin Derivatives in the First Trimester of Pregnancy: A Controversial Story by Sarah D’Alessandro, Elena Menegola, Silvia Parapini, Donatella Taramelli, Nicoletta Basilico

Subjects: “…artemisinins…”
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Artemisinin resistance in <it>Plasmodium falciparum </it>is associated with an altered temporal pattern of transcription by Newton Paul N, Socheat Duong, Russell Bruce, Liong Kek-Yee, Chotivanich Kesinee, Mayxay Mayfong, Yi Poravuth, Ramadoss Ramya, Sim Joan, Mackinnon Margaret J, Imwong Mallika, Mok Sachel, Day Nicholas PJ, White Nicholas J, Preiser Peter R, Nosten François, Dondorp Arjen M, Bozdech Zbynek

Subjects: “…<it>Plasmodium falciparum, in vivo </it>artemisinin-resistance…”
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Bioprospecting of Artemisia genus: from artemisinin to other potentially bioactive compounds by Stefano Negri, Fabio Pietrolucci, Sebastiano Andreatta, Ruth Chinyere Njoku, Carolina Antunes Silva Nogueira Ramos, Massimo Crimi, Mauro Commisso, Flavia Guzzo, Linda Avesani

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Willingness and ability to pay for artemisinin-based combination therapy in rural Tanzania by Montgomery Scott M, Premji Zul, Forsberg Birger C, Saulo Eleonor C, Björkman Anders

“…<p>Abstract</p> <p>Background</p> <p>The aim of this study was to analyse willingness to pay (WTP) and ability to pay (ATP) for ACT for children below five years of age in a rural setting in Tanzania before the introduction of artemisinin-based combination therapy (ACT) as first-line treatment for uncomplicated malaria. …”
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Autophagy Underlies the Proteostasis Mechanisms of Artemisinin Resistance in P. falciparum Malaria by Ananya Ray, Miti Mathur, Deepak Choubey, Krishanpal Karmodiya, Namita Surolia

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No Plasmodium falciparum Chloroquine Resistance Transporter and Artemisinin Resistance Mutations, Haiti by Jeanne P. Vincent, Kanako Komaki-Yasuda, Alexandre V. Existe, Jacques Boncy, Shigeyuki Kano

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Synthesis of Novel Artemisinin, Ciprofloxacin, and Norfloxacin Hybrids with Potent Antiplasmodial Activity by Georgia Vamvoukaki, Antonia I. Antoniou, Michel Baltas, Elisabeth Mouray, Sebastien Charneau, Philippe Grellier, Constantinos M. Athanassopoulos

“…The synthesis and antiplasmodial evaluation of new hybrids combining the pharmacophore structures of artemisinin, ciprofloxacin or norfloxacin, and 7-chloroquinoline are reported in this study. …”
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Artemisinin-Based Antimalarial Drug Therapy: Molecular Pharmacology and Evolving Resistance by Laura E. Heller, Paul D. Roepe

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Polymorphisms in the K13-Propeller Gene in Artemisinin-Resistant Plasmodium in Mice by Zheng S, Liang Y, Wang Z, Liu M, Chen Y, Ai Y, Guo W, Li G, Yuan Y, Xu Z, Wu W, Huang X, Wu Z, Xu Q, Song J, Deng C

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Synthesis and Antiplasmodial Activity of Novel Fosmidomycin Derivatives and Conjugates with Artemisinin and Aminochloroquinoline by Despina Palla, Antonia I. Antoniou, Michel Baltas, Christophe Menendez, Philippe Grellier, Elisabeth Mouray, Constantinos M. Athanassopoulos

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