Polyglutamine-expanded ataxin-3 activates mitochondrial apoptotic pathway by upregulating Bax and downregulating Bcl-xL by An-Hsun Chou, Tu-Hsueh Yeh, Yu-Li Kuo, Yu-Cheng Kao, Mei-Jie Jou, Chia-Yu Hsu, Shu-Ru Tsai, Akira Kakizuka, Hung-Li Wang

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Polyglutamine-expanded ataxin-3 causes cerebellar dysfunction of SCA3 transgenic mice by inducing transcriptional dysregulation by An-Hsun Chou, Tu-Hsueh Yeh, Pin Ouyang, Ying-Ling Chen, Si-Ying Chen, Hung-Li Wang

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HDAC inhibitor sodium butyrate reverses transcriptional downregulation and ameliorates ataxic symptoms in a transgenic mouse model of SCA3 by An-Hsun Chou, Si-Ying Chen, Tu-Hsueh Yeh, Yi-Hsin Weng, Hung-Li Wang

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Sleep Alterations in a Mouse Model of Spinocerebellar Ataxia Type 3 by Maria-Efstratia Tsimpanouli, Anjesh Ghimire, Anna J. Barget, Ridge Weston, Henry L. Paulson, Maria do Carmo Costa, Brendon O. Watson

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A new humanized ataxin-3 knock-in mouse model combines the genetic features, pathogenesis of neurons and glia and late disease onset of SCA3/MJD by Pawel M. Switonski, Wojciech J. Szlachcic, Wlodzimierz J. Krzyzosiak, Maciej Figiel

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Nystagmus may be the first neurological sign in early stages of spinocerebellar ataxia type 3 by Maria Thereza Drumond Gama, Flávio Moura Rezende Filho, Thiago Junqueira Ribeiro Rezende, Pedro Braga Neto, Marcondes Cavalcante França Junior, José Luiz Pedroso, Orlando Graziani Povoas Barsottini

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Downregulation of ATXN3 Enhances the Sensitivity to AKT Inhibitors (Perifosine or MK-2206), but Decreases the Sensitivity to Chemotherapeutic Drugs (Etoposide or Cisplatin) in Neur... by Baocheng Gong, Baocheng Gong, Jinhua Zhang, Zhongyan Hua, Zhongyan Hua, Zhihui Liu, Carol J. Thiele, Zhijie Li, Zhijie Li

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Rescue of ATXN3 neuronal toxicity in Caenorhabditis elegans by chemical modification of endoplasmic reticulum stress by Yasmin Fardghassemi, Arnaud Tauffenberger, Sarah Gosselin, J. Alex Parker

Subjects: “…Ataxin 3…”
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Corrigendum: Downregulation of ATXN3 enhances the sensitivity to AKT inhibitors (Perifosine or MK-2206), but decreases the sensitivity to chemotherapeutic drugs (etoposide or cispl... by Baocheng Gong, Baocheng Gong, Jinhua Zhang, Zhongyan Hua, Zhongyan Hua, Zhihui Liu, Carol J. Thiele, Zhijie Li, Zhijie Li

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Ataxin-3, The Spinocerebellar Ataxia Type 3 Neurodegenerative Disorder Protein, Affects Mast Cell Functions by Anna S. Sowa, Eva Haas, Jeannette Hübener-Schmid, Axel Lorentz

Subjects: “…ataxin-3…”
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Human cytomegalovirus UL97 kinase prevents the deposition of mutant protein aggregates in cellular models of Huntington's disease and Ataxia by Cristy Tower, Lianwu Fu, Rachel Gill, Mark Prichard, Mathieu Lesort, Elizabeth Sztul

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Ataxin-3 Links NOD2 and TLR2 Mediated Innate Immune Sensing and Metabolism in Myeloid Cells by Thomas P. Chapman, Daniele Corridoni, Seiji Shiraishi, Sumeet Pandey, Anna Aulicino, Simon Wigfield, Maria do Carmo Costa, Marie-Laëtitia Thézénas, Henry Paulson, Roman Fischer, Benedikt M. Kessler, Alison Simmons

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The deubiquitinase ataxin-3 requires Rad23 and DnaJ-1 for its neuroprotective role in Drosophila melanogaster by Wei-Ling Tsou, Michelle Ouyang, Ryan R. Hosking, Joanna R. Sutton, Jessica R. Blount, Aaron A. Burr, Sokol V. Todi

Subjects: “…Ataxin-3…”
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Allosteric regulation of deubiquitylase activity through ubiquitination by Serena eFaggiano, Rajesh P. Menon, Geoff P. Kelly, Sokol V. Todi, K. Matthew Scaglione, Petr V. Konarev, Petr V. Konarev, Dmitri I. Svergun, Henry L. Paulson, Annalisa ePastore

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Impaired interactions of ataxin-3 with protein complexes reveals their specific structure and functions in SCA3 Ki150 model by Piotr Piasecki, Kalina Wiatr, Milosz Ruszkowski, Łukasz Marczak, Yvon Trottier, Maciej Figiel

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Targeting the VCP-binding motif of ataxin-3 improves phenotypes in Drosophila models of Spinocerebellar Ataxia Type 3 by Sean L. Johnson, Kozeta Libohova, Jessica R. Blount, Alyson L. Sujkowski, Matthew V. Prifti, Wei-Ling Tsou, Sokol V. Todi

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Toxicity and aggregation of the polyglutamine disease protein, ataxin-3 is regulated by its binding to VCP/p97 in Drosophila melanogaster by Gorica Ristic, Joanna R. Sutton, Kozeta Libohova, Sokol V. Todi

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Ectoine alters subcellular localization of inclusions and reduces apoptotic cell death induced by the truncated Machado–Joseph disease gene product with an expanded polyglutamine s... by Kentaro Furusho, Toshihiro Yoshizawa, Shinichi Shoji

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Altered retinal structure and function in Spinocerebellar ataxia type 3 by Vasileios Toulis, Ricardo Casaroli-Marano, Anna Camós-Carreras, Marc Figueras-Roca, Bernardo Sánchez-Dalmau, Esteban Muñoz, Naila S. Ashraf, Ana F. Ferreira, Naheed Khan, Gemma Marfany, Maria do Carmo Costa

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Machado-Joseph Disease: from first descriptions to new perspectives by Bettencourt Conceição, Lima Manuela

Subjects: “…Ataxin-3…”
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