Awakening the dormant: Role of axonal guidance cues in stress-induced reorganization of the adult prefrontal cortex leading to depression-like behavior by Ashraf Mahmud, Ashraf Mahmud, Radu Gabriel Avramescu, Zhipeng Niu, Cecilia Flores, Cecilia Flores

“…During brain development, axonal guidance cues organize neuronal wiring by directing axonal pathfinding and arborization, dendritic growth, and synapse formation. …”
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The expression pattern of EVA1C, a novel Slit receptor, is consistent with an axon guidance role in the mouse nervous system. by Gregory James, Simon R Foster, Brian Key, Annemiek Beverdam

“…The Slit/Robo axon guidance families play a vital role in the formation of neural circuitry within select regions of the developing mouse nervous system. …”
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SAX-3 (Robo) and UNC-40 (DCC) regulate a directional bias for axon guidance in response to multiple extracellular cues. by Xia Tang, William G Wadsworth

“…How multiple extracellular cues determine the direction of axon guidance is not well understood. We have proposed that an axon's response to guidance cues can be modeled as a random walk, i.e., a succession of randomly directed movement. …”
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Antagonistic Effects of BACE1 and APH1B-γ-Secretase Control Axonal Guidance by Regulating Growth Cone Collapse by Soraia Barão, Annette Gärtner, Eduardo Leyva-Díaz, Galina Demyanenko, Sebastian Munck, Tine Vanhoutvin, Lujia Zhou, Melitta Schachner, Guillermina López-Bendito, Patricia F. Maness, Bart De Strooper

“…Here, we show that this protease is critically involved in semaphorin 3A (Sema3A)-mediated axonal guidance processes in thalamic and hippocampal neurons. …”
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Axon guidance receptor ROBO3 modulates subtype identity and prognosis via AXL-associated inflammatory network in pancreatic cancer by Niklas Krebs, Lukas Klein, Florian Wegwitz, Elisa Espinet, Hans Carlo Maurer, Mengyu Tu, Frederike Penz, Stefan Küffer, Xingbo Xu, Hanibal Bohnenberger, Silke Cameron, Marius Brunner, Albrecht Neesse, Uday Kishore, Elisabeth Hessmann, Andreas Trumpp, Philipp Ströbel, Rolf A. Brekken, Volker Ellenrieder, Shiv K. Singh

“…Using preclinical models, patient-derived xenografts, and FACS-sorted PDAC patient biopsies, we report here that the axon guidance receptor, roundabout guidance receptor 3 (ROBO3), promotes the BL metastatic program via a potentially unique AXL/IL-6/phosphorylated STAT3 (p-STAT3) regulatory axis. …”
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Sensory nerves enhance triple-negative breast cancer invasion and metastasis via the axon guidance molecule PlexinB3 by Thanh T. Le, Samantha L. Payne, Maia N. Buckwald, Lily A. Hayes, Savannah R. Parker, Christopher B. Burge, Madeleine J. Oudin

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RHOA signaling defects result in impaired axon guidance in iPSC-derived neurons from patients with tuberous sclerosis complex by Timothy S. Catlett, Massimo M. Onesto, Alec J. McCann, Sarah K. Rempel, Jennifer Glass, David N. Franz, Timothy M. Gómez

“…TSC2 +/− neurons show impaired mTOR-independent RhoA signaling-mediated axon guidance.…”
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Sensory nerves enhance triple-negative breast cancer invasion and metastasis via the axon guidance molecule PlexinB3 by Le, Thanh T, Payne, Samantha L, Buckwald, Maia N, Hayes, Lily A, Parker, Savannah R, Burge, Christopher B, Oudin, Madeleine J

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Phenotype of V2-derived interneurons and their relationship to the axon guidance molecule EphA4 in the developing mouse spinal cord. by Lundfald, L, Restrepo, C, Butt, S, Peng, C, Droho, S, Endo, T, Zeilhofer, H, Sharma, K, Kiehn, O

“…Furthermore, we demonstrated that a large proportion of V2 interneurons expressed the axon guidance molecule EphA4, a molecule previously shown to be important for correct organization of locomotor networks. …”

Slit-Robo expression in the leech nervous system: insights into eyespot evolution by Hee-Jin Kwak, Brenda I. Medina-Jiménez, Soon Cheol Park, Jung-Hyeuk Kim, Geon-Hwi Jeong, Mi-Jeong Jeon, Sangil Kim, Jung-Woong Kim, David A. Weisblat, Sung-Jin Cho

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Frazzled promotes growth cone attachment at the source of a Netrin gradient in the Drosophila visual system by Orkun Akin, S Lawrence Zipursky

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EphB2 signaling regulates lesion-induced axon sprouting but not critical period length in the postnatal auditory brainstem by Nakamura Paul A, Cramer Karina S

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Axonal cleaved caspase-3 regulates axon targeting and morphogenesis in the developing auditory brainstem by Sarah E Rotschafer, Michelle R Allen-Sharpley, Karina S Cramer

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Midline crossing is not required for subsequent pathfinding decisions in commissural neurons by Bonner Jennifer, Letko Michael, Nikolaus Oliver, Krug Lisa, Cooper Alexandria, Chadwick Benjamin, Conklin Phoebe, Lim Amy, Chien Chi-Bin, Dorsky Richard I

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FGF3 Directs the Pathfinding of Prethalamic GABAergic Axons by Hong Huang, Qingyi Chen, Zhengang Xu, Fang Liu

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FOXP2 exhibits projection neuron class specific expression, but is not required for multiple aspects of cortical histogenesis by Ryan J Kast, Alexandra L Lanjewar, Colton D Smith, Pat Levitt

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Sonic Hedgehog—‘Jack-of-All-Trades’ in Neural Circuit Formation by Nikole R. Zuñiga, Esther T. Stoeckli

Subjects: “…axon guidance…”
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Semaphorin signaling in vertebrate neural circuit assembly by Yutaka eYoshida

Subjects: “…axon guidance…”
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Regulation of nerve growth and patterning by cell surface protein disulphide isomerase by Geoffrey MW Cook, Catia Sousa, Julia Schaeffer, Katherine Wiles, Prem Jareonsettasin, Asanish Kalyanasundaram, Eleanor Walder, Catharina Casper, Serena Patel, Pei Wei Chua, Gioia Riboni-Verri, Mansoor Raza, Nol Swaddiwudhipong, Andrew Hui, Ameer Abdullah, Saj Wajed, Roger J Keynes

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Ascending Midbrain Dopaminergic Axons Require Descending GAD65 Axon Fascicles for Normal Pathfinding by Claudia Marcela Garcia-Peña, Minkyung eKim, Daniela eFrade, Daniela eAvila-Gonzalez, Elisa eTellez, Grant S. Mastick, Elisa eTamariz, Alfredo eVarela-Echavarria

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