Serious drug interactions. by Aronson, J

“…The metabolism of azathioprine is inhibited by allopurinol, and this combination requires a reduced dosage of azathioprine. …”

Azatioprina na doença inflamatória intestinal. by Sílvia Leite, José Manuel Ribeiro, Salomé C Lima, Sónia Barroso, José Cotter

“…Characterisation of an Inflammatory Bowel Disease (IBD) population treated with azathioprine (AZA) and evaluation of AZA safety and efficacy.Retrospective analysis of IBD patients attending our Gastroenterology department in a six months period. …”
Get full text

Immunomodulatory treatment of interstitial lung disease by Laura van den Bosch, Fabrizio Luppi, Giovanni Ferrara, Marco Mura

“…Immunomodulatory agents mainly include corticosteroids, mycophenolate mofetil (MMF), azathioprine, methotrexate, cyclophosphamide and rituximab. …”
Get full text

Autoimmune hepatitis by F Motamed

“…Clear indications for treatment: 1)   rise of aminotrasferases 2)   clinical symptoms of liver disease 3)   histological features in liver biopsy 4)   Children with AIH initial treatment involve glucocorticoid with or without azathioprine. For patients with fulminant hepatitis liver transplantation, should be kept in mind.   …”
Get full text

Postoperative Recurrence of Crohn’s Disease–Is the Early Use of Postoperative Immunomodulators Able to Modify Prognosis? by Maria José Temido, Rui Caetano Oliveira, Andrea Silva, Guilherme Nogueira Fontinha, Sandra Maria Fernandes Lopes, Pedro Figueiredo, Francisco Portela

“…EPI was defined as the restarting or introduction of azathioprine or biologics within 8 weeks after surgery. …”
Get full text

Autoimmune Hepatitis: A Diagnostic and Therapeutic Overview by Lydia A. Mercado, Fernando Gil-Lopez, Razvan M. Chirila, Denise M. Harnois

“…First-line therapy includes high-dose corticosteroids, which are later tapered to decrease side effects, and azathioprine. In the presence of azathioprine intolerance or a poor response to the standard of care, second-line therapy needs to be considered, including mycophenolate mofetil. …”
Get full text

ACTIVE CALCIUM REABSORPTION FOLLOWING KIDNEY TRANSPLANTATION by I. P. Yermakova, I. E. Borodulin, I. A. Pronchenko, N. P. Shmerko

“…It was revealed elevated level of ACR in all patients being maximal in triple immunosupression therapy (cyclosporine, prednisolone, azathioprine) and minimal in double (prednisolone, azathioprine) therapy both in GRF and CR. …”
Get full text

Impact of immunosuppression on the incidence of early subclinical renal allograft rejection: implications for protocol biopsy policy. by Roberts, I, Stratopoulos, C, Zilvetti, M, Reddy, S, Friend, P

“…Patients received cyclosporin (CsA), azathioprine and prednisolone (group 1; n = 304) or IS according to immunological risk (group 2; n = 150). …”

Chronic actinic dermatitis: A clinical study of 15 cases in northern Taiwan by Tzu-Lin Hsiao, Chia-Yu Chu

“…Four patients received azathioprine (50 mg twice a day to every other day) and one received prednisolone (10 mg per day to every other day). …”
Get full text

Immunosuppressive therapy in children with steroid-resistant, frequently-relapsing, and steroid-dependent idiopathic nephrotic syndrome: a single center experience by Bahia Hassan Moustafa, Omar Atef Tolba

“…In group II, the resistance rate was significantly higher with levamisole than with cyclophosphamide and azathioprine (p = 0.046). Leukopenia was reported infrequently after the administration of cyclophosphamide or azathioprine. …”
Get full text

Guidelines for treatment of autoimmune neuromuscular transmission disorders. by Skeie, G, Apostolski, S, Evoli, A, Gilhus, N, Illa, I, Harms, L, Hilton-Jones, D, Melms, A, Verschuuren, J, Horge, H

“…When long-term immunosuppression is necessary, azathioprine is recommended to allow tapering the steroids to the lowest possible dose whilst maintaining azathioprine (recommendation level A). 3,4-Diaminopyridine is recommended as symptomatic treatment and IvIG has a positive short-term effect in LEMS (good practice point). …”

Incidence of cancer in rheumatoid arthritis and other disorders after immunosuppressive treatment. by Kinlen, L

“…A separate analysis of the 643 patients with rheumatoid arthritis found a 13-fold increase of non-Hodgkin's lymphoma (whether treated with azathioprine or cyclophosphamide). This increase is not significantly different from the excess in similarly treated patients with other disorders in the study. …”

Pharmacogenetic Testing for the Pediatric Gastroenterologist: Actionable Drug–Gene Pairs to Know by Tracy Sandritter, Rachel Chevalier, Rebecca Abt, Valentina Shakhnovich

“…Gastroenterologists represent some of the earlier adopters of precision medicine through pharmacogenetic testing by embracing upfront genotyping for thiopurine S-methyltransferase nucleotide diphosphatase (<i>TPMT</i>) before prescribing 6-mercaptopurine or azathioprine for the treatment of inflammatory bowel disease. …”
Get full text

Tjalma syndrome: A rare manifestation of systemic lupus erythematosus by Ashwaq Alhmoudi, Ahlam Almarzooqi, Maryam Alahmad, Amna Al Muhairi, Sehriban Diab, Raven Haan, Khalid Elsayed

“…Prednisolone was tapered down and azathioprine was added as a steroid-sparing agent. The patient eventually had complete remission of her symptoms, as well as remarkable improvements in her laboratory results. …”
Get full text

Clinical characteristics and prognostic factors of fibrotic nonspecific interstitial pneumonia by Hyun Kyu Cho, Man Pyo Chung, Kyung Soo Lee, Myung Jin Chung, Joungho Han, O Jung Kwon, Hongseok Yoo

“…Conclusion: Preserved lung function, BAL lymphocytosis, and treatment with corticosteroids and azathioprine were associated with lower risks of disease progression and relapse, which were risk factors for mortality.…”
Get full text

Systemic treatment for severe atopic dermatitis in children: a case series by Orly Cheirif-Wolosky, Itzel G. Elizalde-Jiménez, María T. García-Romero

“…The drugs used were methotrexate (57.1%), thalidomide (38%), prednisone (42.8%), azathioprine (19%), mycophenolate mofetil (9.5%), cyclosporine (4.7%), and systemic steroids as bridging therapy (42.8%). …”
Get full text

Propylthiouracil-Induced Antineutrophil Cytoplasmic Antibodies-Associated Vasculitis with Renal and Lung Involvement by Albert Hing Wong, Wei-Kei Wong, Lai-Meng Looi, Jeyakantha Ratnasingam, Soo-Kun Lim

“…She remained well on azathioprine 50 mg daily as maintenance therapy and clinically euthyroid with carbimazole 2.5 mg daily. …”
Get full text

Clinical Features and Histological Findings of 17 Patients with Chronic Actinic Dermatitis by Min Soo Jang, Kang Hoon Lee, Sang Hwa Han, Jong Bin Park, Dong Young Kang, Sang Tae Kim, Kee Suck Suh

“…Topical steroid, tacrolimus and systemic cyclosporine, azathioprine are effective in treating chronic actinic dermatitis.…”
Get full text

The prevalence of hyperlipidemia in renal transplant recipients. Associations with immunosuppressive and antihypertensive therapy. by Bittar, A, Ratcliffe, P, Richardson, A, Raine, A, Jones, L, Yudkin, P, Carter, R, Mann, J, Morris, P

“…Plasma cholesterol, HDL cholesterol, and triglyceride levels were almost identical in patients receiving triple therapy (cyclosporine 3-5 mg/kg; prednisolone 7-10 mg o.d.; azathioprine 1-1.5 mg/kg) to those in patients receiving conventional immunosuppression (prednisolone 7-10 mg o.d.; azathioprine 2-2.5 mg/kg). …”

O-43 RISK FACTORS FOR CANCER DEVELOPMENT IN PATIENTS WITH PRIMARY BILIARY CHOLANGITIS by Michelle Harriz Braga, Guilherme Grossi Lopes Cançado, Paulo Lisboa Bittencourt, Cláudia Alves Couto, Laura Vilar Guedes, André Mourão Costa Lima, Maria Lucia Gomes Ferraz, Cristiane Alves Villela-Nogueira, Jorge Nardelli Mateus, Luciana Costa Faria, Nathalia Mota De Faria Gomes, Maria Gomes Oliveira Elze, Vivian Rotman, Maria Beatriz Oliveira, Simone Muniz Carvalho Fernandes Cunha, Marlone Cunha-Silva, Liliana Sampaio Costa Mendes, Claudia Alexandra Pontes Ivantes, Liana Codes, Valéria Ferreira De Almeida Borges, Fabio Heleno De Lima Pace, Mario Guimarães Pessoa, Izabelle Venturini Signorelli, Gabriela Perdomo Coral, João Galizzi Filho, Aline Lopes Chagas, Debora Raquel Benedita Terrabuio, Eduardo Luiz Rachid Cançado

“…In multivariate analysis, cirrhosis, obesity and prior azathioprine therapy were independent risk factors for HCC, while Sjogren syndrome and psoriasis were associated with EHM. …”
Get full text