Terapêutica imunosupressora na miocardiopatia periparto. by E Macieira-Coelho, D Brito, H Madeira

“…The dramatic clinical recuperation of a thirty years old, Caucasian female, with peripartum cardiomyopathy, treated with azathioprine and prednisolone, is described. The maintenance of the same degree of ventricular dilatation and fractional shortening (14%) on serial echocardiograms inspite of complete regression of cardiac congestion was the most intriguing feature of this clinical case.…”
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Co occurrence of Hepatitis B Virus Infection and Autoimmune Hepatitis with Marked Hepatitis B Virus Replication Following Treatment of Autoimmune Hepatitis by Tyagi I, Puri AS, Sakhuja P, Majumdar K, Jain G

“…Patient was started on treatment with azathioprine and prednisolone for AIH following which clinical and biochmemical improvement was noted. …”
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Chronic ulcerative Cutaneous Vasculitis of the legs Clinical and histopathological study by Thamir A. Hamed, Hayder R. Al-Hamamy, Husam A. Salman, Mukram M Al-Waiz

“…In addition, evaluation of the clinical response to prednisolone 0.5mg/kg/day and azathioprine150mg/day was done. Results: Thirteen patients were included in this study; eight females and five males, with male to female ratio of 1:1.6. …”
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A Multidisciplinary Approach to the Management of Eales Disease: A Case Report and Review of the Literature by Maria Filoftea Mercuț, Oana Maria Ică, Cornelia Andreea Tănasie, Răzvan Mercuț, Carmen Luminița Mocanu, Andreea Mihaela Nicolcescu, Ciprian Danielescu

“…The patient underwent bilateral retinal laser pan-photocoagulation, followed by systemic treatment with oral steroids, cephazoline, isoniazid, azathioprine, and entecavir. The steroid dose was progressively reduced over 10 months; the treatment with azathioprine continues, as we are monitoring the patient over the long term. …”
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Neuromyelitis optica spectrum disorder safely and successfully treated with satralizumab during pregnancy and breastfeeding: a case report by Takashi Yoshida, Takashi Yoshida, Osamu Watanabe, Miwa Nomura, Yusuke Yoshimoto, Yoshimitsu Maki, Hiroshi Takashima

“…Despite responding to steroid and azathioprine therapy, she experienced moon face and weight gain and desired the prompt reduction of the steroid dosage. …”
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Treatment of Overlap Syndromes in Autoimmune Liver Disease: A Systematic Review and Meta-Analysis by Benjamin L. Freedman, Christopher J. Danford, Vilas Patwardhan, Alan Bonder

“…Combination therapy may therefore be superior to both UDCA and corticosteroids ± azathioprine for the treatment of AIH-PBC, but additional studies are needed to show this definitively and to elucidate optimal treatments for other overlap syndromes.…”
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Efficacy of hepatitis B vaccination in patients with ulcerative colitis: a prospective cohort study by Anurag Mishra, Amarender Singh Puri, Sanjeev Sachdeva, Ashok Dalal

“…Multivariate analysis revealed that only non-exposure to corticosteroids, azathioprine and biologicals, male sex, and disease duration <5 years were independent predictors of AIR. …”
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Transcriptomic analysis of inflammatory cardiomyopathy identifies molecular signatures of disease and informs in silico prediction of a network-based rationale for therapy by Singh, K, Fang, H, Davies, G, Wright, B, Lockstone, H, Williams, RO, Ciháková, D, Knight, JC, Bhattacharya, S

“…The immunosuppressive agents such as prednisolone, azathioprine and cyclosporine are modestly effective treatments, but a molecular rationale underpinning such therapy or the development of new therapeutic strategies is lacking. …”

The utilisation of biomarkers of a reduced immune response to predict squamous cell carcinoma in long-term renal transplant recipients by Bottomley, M

“…</p> <p>Signatures of operational tolerance did not predict SCC risk but were heavily influenced by the effect upon circulating B cells due to immunosuppressive regime, particularly azathioprine and calcineurin inhibition. Further evaluation indicated that azathioprine use was associated with the presence of donor-specific antibodies.…”

Guidelines for the treatment of autoimmune neuromuscular transmission disorders. by Skeie, G, Apostolski, S, Evoli, A, Gilhus, N, Hart, I, Harms, L, Hilton-Jones, D, Melms, A, Verschuuren, J, Horge, H

“…(vii) In patients where long-term immunosuppression is necessary, azathioprine is recommended together with steroids to allow tapering the steroids to the lowest possible dose whilst maintaining azathioprine (level A recommendation). …”

Specific and non-specific suppression of renal allograft rejection in the rat by Winearls, C, Winearls, Christopher Good

“…</p> <p xmlns:etd="http://www.ouls.ox.ac.uk/ora/modsextensions">The potentiation of the partial immunosuppressive effect of passive enhancement was found to be possible with suboptimal doses of antilymphocyte serum or cyclophosphamide but not azathioprine and prednisolone. Moreover, the use of high doses of azathioprine with enhancing serum resulted in significantly shorter survival times than those seen with enhancing serum alone. …”

Therapeutic monitoring of thiopurine metabolites : validation of an HPLC method and preliminary findings from a small cohort of Malaysian patients with inflammatory bowel disease by Lim, Sheng Zhang, Raja Affendi Raja Ali, Suzana Makpol, Chua, Eng Wee

“…They were classified as responders (n = 12) or non-responders (n = 6) to azathioprine based on their disease activity scores (CDAI or Mayo score). …”
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Review: Immunomodulators for all patients with inflammatory bowel disease? by Sandro Ardizzone, Andrea Cassinotti, Gianpiero Manes, Gabriele Bianchi Porro

“…We review the recommended or suggested use of conventional immunomodulators such as azathioprine, 6-mercaptopurine, methotrexate in the treatment of IBD. …”
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Autoimmunity to insulin receptor and hypoglycaemia in patient with Hodgkin's disease. by Braund, W, Naylor, B, Williamson, D, Buley, I, Clark, A, Chapel, H, Turner, R

“…The hypoglycaemia did not respond to plasmapheresis or azathioprine alone, but it remitted after the addition of prednisolone, and the erythrocyte receptor binding of insulin became normal.…”

Autoimmune hepatitis with superimposition of primary sclerosing cholangitis on non-specific chronic ulcerative colitis by JS Sandoval Mendoza, L Juárez Chávez, DG Ibarra Salazar

“…He received steroid, azathioprine, ursodeoxycholic acid and mesalazine. Treated latent TB. …”
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Immunological Remission as a Basis for Dose Reduction of Immunosuppressors in Autoimmune Hepatitis: Results of Monocenter Surveillance Study by A. O. Bueverov, S. V. Koblov, P. O. Bogomolov

“…The most used combination was prednisolone and azathioprine — in 25 patients (53.2 %), as well as methylprednisolone and azathioprine — in 8 patients (17 %).Results. …”
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De Novo Carcinoma after Solid Organ Transplantation to Give Insight into Carcinogenesis in General—A Systematic Review and Meta-Analysis by Eline S. Zwart, Esen Yüksel, Anne Pannekoek, Ralph de Vries, Reina E. Mebius, Geert Kazemier

“…Patients receiving azathioprine had higher odds to develop de novo carcinomas compared to mycophenolate (OR3.34, 95%CI 1.29–8.65) and head and neck carcinoma compared to tacrolimus (OR3.78, 95%CI 1.11–12.83). …”
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Clinical profile and management with immunosuppressants and biologics in Behcet's uveitis: A cohort of 25 patients from a tertiary eye care center in South India by Jeyasooriya Ramdoss, Prerana Singh, Arshee S Ahmed, Jyotirmay Biswas

“…Immunosuppressive agents along with steroids were given in 20 patients (80%), of which azathioprine alone was given in seven patients (28%), cyclosporin alone was given in two patients (8%), mycophenolate mofetil alone was given in three patients (12%), combination of azathioprine and cyclosporin was given in six patients (24%), and combination of methotrexate and mycophenolate mofetil was given in one patient (4%). …”
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IgG4-Related Chronic Sinonasal Pseudotumor with Refractory Nasal Bleeding: A Case Report by Hsu-Lin Lee, Meng-Ko Tsai, Deng-Ho Yang

“…This report highlights that in cases with an inflammatory mass mimicking malignancy, IgG4RD should always be considered, and rituximab treatment is recommended upon failure of steroid and azathioprine therapy.…”
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Different clinical phenotypes of AQP4-IgG positive NMOSD in two first degree relatives by Salvatore Ssemmanda, Abdu Kisekka Musubire

“…She stabilized on tapered doses of oral Prednisone and continues daily oral Azathioprine with moderate improvement in her vision and no further relapses as yet. …”
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