Identification of Rare Mutations of Two Presynaptic Cytomatrix Genes <i>BSN</i> and <i>PCLO</i> in Schizophrenia and Bipolar Disorder by Chia-Hsiang Chen, Yu-Shu Huang, Ding-Lieh Liao, Cheng-Yi Huang, Chia-Heng Lin, Ting-Hsuan Fang

“…This report identified a rare missense mutation Arg1087Gln of <i>BSN</i> (bassoon presynaptic cytomatrix protein) co-segregating with schizophrenia in a family with multiple affected members. …”
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Critical Role of the Presynaptic Protein CAST in Maintaining the Photoreceptor Ribbon Synapse Triad by Akari Hagiwara, Ayako Mizutani, Saki Kawamura, Manabu Abe, Yamato Hida, Kenji Sakimura, Toshihisa Ohtsuka

“…These proteins interact with other active zone proteins, including RIMs, Munc13s, Bassoon, and the β subunit of Ca²⁺ channels, and have various roles in neurotransmitter release. …”
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Analysis of protein phosphorylation in nerve terminal reveals extensive changes in active zone proteins upon exocytosis by Mahdokht Kohansal-Nodehi, John JE Chua, Henning Urlaub, Reinhard Jahn, Dominika Czernik

“…Particularly pronounced were regulated changes of phosphosites within protein constituents of the presynaptic active zone, including bassoon, piccolo, and RIM1. Additionally, we have mapped kinases and phosphatases that are activated upon stimulation. …”
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Pre- and postsynaptic nanostructures increase in size and complexity after induction of long-term potentiation by Valérie Clavet-Fournier, ChungKu Lee, Waja Wegner, Nils Brose, JeongSeop Rhee, Katrin I. Willig

“…We utilized time-lapse super-resolution STED microscopy of organotypic hippocampal brain slices and cultured neurons to visualize structural changes of the synaptic nano-organization of the postsynaptic scaffolding protein PSD95, the presynaptic scaffolding protein Bassoon, and the GluA2 subunit of AMPA receptors by chemically induced long-term potentiation (cLTP) at the level of single synapses. …”
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Visualizing the triheteromeric N-methyl-D-aspartate receptor subunit composition by Stephen Beesley, Akash Gunjan, Sanjay S. Kumar

“…Even though structural information about individual receptors is still diffraction limited, fluorescently tagged receptor subunit puncta coalesce with precision at various magnifications and/or with the postsynaptic density (PSD-95) but not the presynaptic active zone marker Bassoon. These data are particularly relevant for identifying GluN3A-containing t-NMDARs that are highly Ca2+ permeable and whose expression at excitatory synapses renders neurons vulnerable to excitotoxicity and cell death. …”
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Multi-Omics Analysis Reveals Myelin, Presynaptic and Nicotinate Alterations in the Hippocampus of G72/G30 Transgenic Mice by Michaela D. Filiou, Larysa Teplytska, Markus Nussbaumer, David-M. Otte, Andreas Zimmer, Christoph W. Turck

“…Our proteomics analysis revealed decreased expression of myelin-related proteins and NAD-dependent protein deacetylase sirtuin-2 (Sirt2) as well as increased expression of the scaffolding presynaptic proteins bassoon (Bsn) and piccolo (Pclo) and the cytoskeletal protein plectin (Plec1) in G72Tg compared to wild-type (WT) mice. …”
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Proteomic Analysis Unveils Expressional Changes in Cytoskeleton- and Synaptic Plasticity-Associated Proteins in Rat Brain Six Months after Withdrawal from Morphine by Zdenka Drastichova, Lucie Hejnova, Radka Moravcova, Jiri Novotny

“…More specifically, significant changes were observed in proteins localized in synaptic vesicles (e.g., synapsin-1, SV2a, Rab3a), in the active zone of the presynaptic nerve terminal (e.g., Bassoon, Piccolo, Rims1), and in the postsynaptic density (e.g., cadherin 13, catenins, Arhgap35, Shank3, Arhgef7). …”
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Features of the modern saxophone by Stepanova Anna

“…In the historical aspect, some theoretical works of domestic and foreign authors on the methods and techniques of playing the saxophone have been analysed: the American researcher Carr W.E.J., who identified the physiological features of playing wooden wind instruments (the flute, the oboe, the clarinet, the bassoon and the saxophone); the Russian Professor Ivanov V. …”
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Aerosol emissions from wind instruments: effects of performer age, sex, sound pressure level, and bell covers by John Volckens, Kristen M. Good, Dan Goble, Nicholas Good, Joshua P. Keller, Amy Keisling, Christian L’Orange, Emily Morton, Rebecca Phillips, Ky Tanner

“…We evaluated aerosol number emissions (from 0.25 to 35.15 μm) from 81 volunteer performers of both sexes and varied age (12 to 63 years) while playing wind instruments (bassoon, clarinet, flute, French horn, oboe, piccolo, saxophone, trombone, trumpet, and tuba) or singing. …”
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Rapid sequential clustering of NMDARs, CaMKII, and AMPARs upon activation of NMDARs at developing synapses by Yucui Chen, Shangming Liu, Ariel A. Jacobi, Grace Jeng, Jason D. Ulrich, Ivar S. Stein, Ivar S. Stein, Tommaso Patriarchi, Johannes W. Hell, Johannes W. Hell

“…We find that in cultures of dissociated hippocampal neurons at 11 days in vitro (DIV) numerous synaptic contacts already exhibit pronounced accumulations of the pre- and postsynaptic markers synaptotagmin, synaptophysin, synapsin, bassoon, VGluT1, PSD-95, and Shank. The presence of an initial set of AMPARs and NMDARs is indicated by miniature excitatory postsynaptic currents (mEPSCs). …”
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Temporal lobe proteins implicated in synaptic failure exhibit differential expression and deamidation in vascular dementia by Gallart-Palau, Xavier, Serra, Aida, Qian, Jingru, Chen, Christopher P., Kalaria, Raj N., Sze, Siu Kwan

“…Brain tissue from VaD patients exhibited significant down-regulation of critical synaptic proteins including clathrin (0.29 ; p<1.0•10-3) and GDI1 (0.51 ; p=3.0•10-3), whereas SNAP25 (1.6 ; p=5.5•10-3), bassoon (1.4 ; p=1.3•10-3), excitatory aminoacid transporter 2 (2.6 ; p=9.2•10-3) and Ca2+/calmodulin dependent kinase II (1.6 ; p=3.0•10-2) were substantially up-regulated. …”
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The role of RIM in neurotransmitter release: promotion of synaptic vesicle docking, priming, and fusion by Shanshan Wu, Shanshan Wu, Jiali Fan, Jiali Fan, Fajuan Tang, Fajuan Tang, Lin Chen, Lin Chen, Xiaoyan Zhang, Xiaoyan Zhang, Dongqiong Xiao, Dongqiong Xiao, Xihong Li, Xihong Li

“…The cytomatrix in the active zone (CAZ) is made up of proteins such as the regulating synaptic membrane exocytosis protein (RIM), RIM-binding proteins (RIM-BPs), ELKS/CAST, Bassoon/Piccolo, Liprin-α, and Munc13-1. RIM is a scaffold protein that interacts with CAZ proteins and presynaptic functional components to affect the docking, priming, and fusion of SVs. …”
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Visualizing Arc protein dynamics and localization in the mammalian brain using AAV-mediated in situ gene labeling by Martino Avallone, Joaquín Pardo, Joaquín Pardo, Tadiwos F. Mergiya, Tadiwos F. Mergiya, Jana Rájová, Atte Räsänen, Marcus Davidsson, Malin Åkerblom, Luis Quintino, Darshan Kumar, Clive R. Bramham, Clive R. Bramham, Tomas Björklund

“…Finally, we recorded mCherry-Arc interaction with presynaptic protein Bassoon in mCherry-negative surrounding neurons at close proximity to mCherry-positive spines of edited neurons. …”
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Recognizing Similar Musical Instruments with YOLO Models by Christine Dewi, Abbott Po Shun Chen, Henoch Juli Christanto

“…Cellos, clarinets, erhus, guitars, saxophones, trumpets, French horns, harps, recorders, bassoons, and violins were all classified in this investigation. …”
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Modern brass band: its components and activities by Stepanova Anna

“…In addition, the "large mixed brass band" has a much more complete group of wooden wind instruments, consisting of three flutes (piccolo flute and two large flutes), two oboes, the English horn, a large group of clarinets with their varieties, two bassoons, contraphagot and saxophones. To provide low-register sounds, helicons are introduced into the "large mixed brass band" – a low-sounding brass instrument arranged in a circle. …”
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