Bazooka wird Booster by Lennart Laude, Nicolas Harding

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Bazooka mediates secondary axon morphology in <it>Drosophila </it>brain lineages by Hartenstein Volker, Spindler Shana R

“…Exogenous expression of Bazooka protein in BAla1 neurons rescued defective guidance, supporting an intrinsic requirement for Bazooka in the post-mitotic neuron. …”
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Arthroscopic Management of Juxta-articular Proximal Humeral Chondroblastoma: The Bazooka Technique by Mohamed Gamal Morsy, M.D., Hesham Mohamed Gawish, M.D.

“…Few reports have documented the use of arthroscopy in tumor surgery owing to the problem of inadequate removal and the difficulty of bone graft delivery to the tumor cavity. The bazooka technique should solve these 2 main problems. …”
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Bazooka/PAR3 is dispensable for polarity in Drosophila follicular epithelial cells by Jaffer Shahab, Manu D. Tiwari, Mona Honemann-Capito, Michael P. Krahn, Andreas Wodarz

“…It has been proposed that Bazooka operates at the top of a genetic hierarchy in the establishment and maintenance of apico-basal polarity. …”
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Peptide binding properties of the three PDZ domains of Bazooka (Drosophila Par-3). by Cao Guo Yu, Raffi Tonikian, Corinna Felsensteiner, Jacquelyn R Jhingree, Darrell Desveaux, Sachdev S Sidhu, Tony J C Harris

“…The Par complex is a conserved cell polarity regulator. Bazooka/Par-3 is scaffold for the complex and contains three PDZ domains in tandem. …”
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A modifier screen for Bazooka/PAR-3 interacting genes in the Drosophila embryo epithelium. by Wei Shao, Johnny Wu, Jeyla Chen, Donghoon M Lee, Alisa Tishkina, Tony J C Harris

“…BACKGROUND:The development and homeostasis of multicellular organisms depends on sheets of epithelial cells. Bazooka (Baz; PAR-3) localizes to the apical circumference of epithelial cells and is a key hub in the protein interaction network regulating epithelial structure. …”
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Magi Is Associated with the Par Complex and Functions Antagonistically with Bazooka to Regulate the Apical Polarity Complex. by Mojgan Padash Barmchi, Gayathri Samarasekera, Mary Gilbert, Vanessa J Auld, Bing Zhang

“…Magi is localized at the adherens junction and forms a complex with the polarity proteins, Par3/Bazooka and aPKC. We generated a Magi null mutant and found that Magi null mutants were viable with no detectable morphological defects even though the Magi protein is highly conserved with vertebrate Magi homologues. …”
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Cytoskeletal tension and Bazooka tune interface geometry to ensure fusion fidelity and sheet integrity during dorsal closure by Piyal Taru Das Gupta, Maithreyi Narasimha

“…We show that fusing cell interfaces are remodelled from en-face contacts at fusion to an interlocking arrangement after fusion, and demonstrate that changes in interface length and geometry are dependent on the spatiotemporal regulation of cytoskeletal tension and Bazooka/Par3. Our work uncovers genetically constrained and mechanically triggered adaptive mechanisms contributing to fusion fidelity and epithelial continuity.…”
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Pak4 Is Required during Epithelial Polarity Remodeling through Regulating AJ Stability and Bazooka Retention at the ZA by Rhian F. Walther, Francisca Nunes de Almeida, Evi Vlassaks, Jemima J. Burden, Franck Pichaud

“…We find that β-catenin phosphorylation by Mbt, and associated AJ morphogenesis, is needed for the retention of the apical determinant Par3/Bazooka at the remodeling ZA. Importantly, this retention mechanism functions together with Par1-dependent lateral exclusion of Par3/Bazooka to regulate apical membrane differentiation. …”
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Par3/Bazooka and phosphoinositides regulate actin protrusion formation during Drosophila dorsal closure and wound healing. by Pickering, K, Alves-Silva, J, Goberdhan, D, Millard, T

“…We find that the scaffolding protein Par3/Bazooka and the lipid phosphatase Pten are specifically lost from cell-cell junctions at epithelial edges. …”

Meru couples planar cell polarity with apical-basal polarity during asymmetric cell division by Jennifer J Banerjee, Birgit L Aerne, Maxine V Holder, Simon Hauri, Matthias Gstaiger, Nicolas Tapon

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PAR-Complex and Crumbs Function During Photoreceptor Morphogenesis and Retinal Degeneration by Franck Pichaud

“…The conserved PAR complex, which in flies consists of Cdc42-PAR6-aPKC-Bazooka, and the transmembrane protein Crumbs (Crb) are key players during photoreceptor morphogenesis. …”
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Par3 cooperates with Sanpodo for the assembly of Notch clusters following asymmetric division of Drosophila sensory organ precursor cells by Elise Houssin, Mathieu Pinot, Karen Bellec, Roland Le Borgne

“…Notch is preferentially targeted to the pIIa-pIIb interface, where it co-clusters with Bazooka and its cofactor Sanpodo. Clusters whose assembly relies on Bazooka and Sanpodo activities are also positive for Neuralized, the E3 ligase required for Delta activity. …”
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Regulated and polarized PtdIns(3,4,5)P3 accumulation is essential for apical membrane morphogenesis in photoreceptor epithelial cells. by Pinal, N, Goberdhan, D, Collinson, L, Fujita, Y, Cox, I, Wilson, C, Pichaud, F

“…BACKGROUND: In a specialized epithelial cell such as the Drosophila photoreceptor, a conserved set of proteins is essential for the establishment of polarity, its maintenance, or both--in Drosophila, these proteins include the apical factors Bazooka, D-atypical protein kinase C, and D-Par6 together with D-Ecadherin. …”

How to Be Happy, Dammit : A Cynic's Guide to Spritual Happiness / by Salmansohn, Karen 536347

“…Guaranteed to perk up even the most cynical spirit, HOW TO BE HAPPY, DAMMIT is the first and only self-help book that merges psychology, biology, eastern and western philosophies, quantum physics, and the Zen of Bazooka Joe. Think love and happiness have passed you by? …”

Notkredite immer und überall? by Lennart Laude, Nicolas Harding

“…<p>Spätestens seit der Corona-Krise und den damit verbundenen Haushaltspaketen von Bazooka bis Booster scheinen großangelegte Investitionsprogramme zum (haushalts-)politischen Alltag zu gehören. …”
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Protein clustering for cell polarity: Par-3 as a paradigm [version 1; referees: 3 approved] by Tony J. C. Harris

“…The scaffold protein Par-3 (Drosophila Bazooka) is a central organizer of cell polarity across animals. …”
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Asymmetric recruitment and actin-dependent cortical flows drive the neuroblast polarity cycle by Chet Huan Oon, Kenneth E Prehoda

“…Initially, the Par proteins aPKC and Bazooka form discrete foci at the apical cortex. Foci grow into patches that together comprise a discontinuous, unorganized structure. …”
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Partial Functional Diversification of Drosophila melanogaster Septin Genes Sep2 and Sep5 by Ryan S. O’Neill, Denise V. Clark

“…We also find that mutations in septins enhance the mutant phenotype of bazooka, a key component in the establishment of cell polarity, suggesting a link between septin function and cell polarity. …”
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An alternative mode of epithelial polarity in the Drosophila midgut. by Jia Chen, Aram-Christopher Sayadian, Nick Lowe, Holly E Lovegrove, Daniel St Johnston

“…Studies in Drosophila have identified conserved polarity factors that define the apical (Crumbs, Stardust, Par-6, atypical protein kinase C [aPKC]), junctional (Bazooka [Baz]/Par-3), and basolateral (Scribbled [Scrib], Discs large [Dlg], Lethal [2] giant larvae [Lgl]) domains of epithelial cells. …”
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