Electrical Pacing of Cardiac Tissue Including Potassium Inward Rectification. by Suran Galappaththige, Bradley J Roth

“…Numerical simulations were carried out using the bidomain model with potassium dynamics specified to be inward rectifying. …”
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A numerical method for cardiac mechanoelectric simulations. by Pathmanathan, P, Whiteley, J

“…Much effort has been devoted to developing numerical techniques for solving the equations that describe cardiac electrophysiology, namely the monodomain equations and bidomain equations. Only a limited selection of publications, however, address the development of numerical techniques for mechanoelectric simulations where cardiac electrophysiology is coupled with deformation of cardiac tissue. …”

A Numerical Method for Cardiac Mechanoelectric Simulations by Pathmanathan, P, Whiteley, J

“…Much effort has been devoted to developing numerical techniques for solving the equations that describe cardiac electrophysiology, namely the monodomain equations and bidomain equations. Only a limited selection of publications, however, address the development of numerical techniques for mechanoelectric simulations where cardiac electrophysiology is coupled with deformation of cardiac tissue. …”

New developments in an anatomical framework for modeling cardiac ischemia by Smith, N, Stevens, C, Pullan, A, Hunter, P, Mulquiney, P

“…The mechanics model is coupled via myocardial wall stress, to a one-dimensional coronary blood flow model embedded in the myocardium. Bidomain electrical activation of the myocardium. is also modeled, with ionic current based electrophysiological equations and reaction-diffusion equations based on orthotropic conductivity tensors referred to the fibrous-sheet material axes. …”

The Role of Blood Vessels in Rabbit Propagation Dynamics and Cardiac Arrhythmias by Gibb, M, Bishop, M, Burton, R, Kohl, P, Grau, V, Plank, G, Rodriguez, B

“…We simulate propagation following different stimulation protocols around a transmural and a sub-epicardial vessel, using both bidomain and monodomain representations. We demonstrate the importance of accurately modelling the fibre structure around blood vessels relative to a simplistic transmurally varying fibre orientation model and suggest how this may impact pro-arrhythmic electrical dynamics. © 2009 Springer Berlin Heidelberg.…”

Mechanisms underlying cardiac vulnerability to electric shocks within the three-dimensional volume of the rabbit ventricles by Maharaj, T, Rodriguez, B, Blake, R, Trayanova, N, Gavaghan, D

“…This study used a three-dimensional, geometrically accurate finite element bidomain model of the rabbit ventricles. Transmural heterogeneities in ionic currents were incorporated based on experimental data to generate the transmural APD profile recorded in adult rabbits during pacing. …”

Transmural electrophysiological heterogeneities in action potential duration increase the upper limit of vulnerability. by Maharaj, T, Rodriguez, B, Blake, R, Trayanova, N, Gavaghan, D

“…This study used a three- dimensional, geometrically accurate finite element bidomain rabbit ventricular model. Transmural heterogeneities in ionic currents were incorporated based on experimental data to generate the transmural APD profile recorded in adult rabbits during pacing. …”

Simulating Drug-Induced Effects on the Heart: From Ion Channel to Body Surface Electrocardiogram by Zemzemi, N, Bernabeu, M, Saiz, J, Rodriguez, B

“…In the present study, we present a computational model of the human ECG capable of representing drug-induced effects from the ionic to the surface potential level. Bidomain simulations are conducted to simulate the electrophysiological activity of the heart and extracellular potentials in the whole body. …”

On Berry's conjectures about the stable order in PCF by Fritz Müller

“…He made the following two conjectures: 1) "Extensional and stable order form not only a bicpo, but a bidomain." We refute this conjecture by showing that the stable order is not bounded complete, already for finitary PCF of second-order types. 2) "The stable order of the model has the syntactic order as its image: If a is less than b in the stable order of the model, for finite a and b, then there are normal form terms A and B with the semantics a, resp. b, such that A is less than B in the syntactic order." …”
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Automatically generated, anatomically accurate meshes for cardiac electrophysiology problems. by Prassl, A, Kickinger, F, Ahammer, H, Grau, V, Schneider, J, Hofer, E, Vigmond, E, Trayanova, N, Plank, G

“…The numerical feasibility of the approach is demonstrated by discretizing and solving the monodomain and bidomain equations on the generated grids for two preparations of high experimental relevance, a left ventricular wedge preparation, and a papillary muscle.…”

Transmural electrophysiological heterogeneities in action potential duration increase the upper limit of vulnerability. by Maharaj, T, Rodriguez, B, Blake, R, Trayanova, N, Gavaghan, D

“…This study used a three- dimensional, geometrically accurate finite element bidomain rabbit ventricular model. Transmural heterogeneities in ionic currents were incorporated based on experimental data to generate the transmural APD profile recorded in adult rabbits during pacing. …”

In vitro reconstitution of the catabolic reactions catalyzed by PcaHG, PcaB, and PcaL: the protocatechuate branch of the beta-ketoadipate pathway in Rhodococcus jostii RHA1 by Yamanashi, Tomoya, Kim, Seungyoung, Hara, Hirofumi, Funa, Nobutaka

“…In addition, the in vitro reaction of PcaL, a bidomain protein consisting of y-carboxy-muconolactone decarboxylase and ß-ketoadipate enol-lactone hydrolase activities, was demonstrated for the first time. …”

Modelling the effect of gap junctions on tissue-level cardiac electrophysiology by Doug Bruce, Pras Pathmanathan, Jonathan P. Whiteley

“…One of the most commonly used models is represented by the bidomain equations, the derivation of which relies on a homogenisation technique to construct a suitable approximation to the discrete model. …”
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The role of photon scattering in optical signal distortion during arrhythmia and defibrillation. by Bishop, M, Rodriguez, B, Qu, F, Efimov, I, Gavaghan, D, Trayanova, N

“…A three-dimensional realistic bidomain rabbit ventricular model was combined with a model of photon transport. …”

Altered T wave dynamics in a contracting cardiac model by Smith, N, Buist, M, Pullan, A

“…Waves of activation and contraction are induced by the application of physiologically realistic boundary conditions and solving the bidomain and finite deformation equations. Body surface potentials are calculated from these activation profiles by solving Laplace's equation in the passive surrounding tissues. …”

Effect of thermal cycle on the interfacial antiferromagnetic spin configuration and exchange bias in Ni-Mn-Sb alloy by R. L. Wang, M. K. Lee, L. S. Xu, Z. G. Sun, V. V. Marchenkov, C. Tien, J. C. A. Huang, C. P. Yang

“…The evolutions can be illustrated intuitively by a simple AFM bidomain model.…”
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Spatial Sensitivity of ECG Electrode Placement by Oltmann Andra, Kusche Roman, Rostalski Philipp

“…The electrical excitation of the heart is modelled on a cellular level via the bidomain approach. To numerically solve the differential equations, describing the signal propagation within the body, we use the finite element method in COMSOL Multiphysics®. …”
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A combined functional dorsal nerve model of the foot by Muhammad Z. Ul Haque, Peng Du, Leo K. Cheng

“…The unmyelinated as well as myelinated electrophysiological nerve models were used to simulate selected SUSSN and MLN of the foot by injecting an external stimulus at the most distal part of SUSSN of the foot through the use of bidomain model. Results from our work demonstrated that the action potential propagated from the most distal part to proximal part of distinct dorsal nerves of the foot, e.g., the simulated NCV of the combined intermediate dorsal cutaneous nerve (IDCN) of the foot was 28.4 m s-1. …”
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Structural insights into the substrate-bound condensation domains of non-ribosomal peptide synthetase AmbB by Melissa-Jane Chu Yuan Kee, Sakshibeedu R. Bharath, Sheena Wee, Matthew W. Bowler, Jayantha Gunaratne, Shenquan Pan, Lianhui Zhang, Haiwei Song

“…We determined crystal structures of the truncated T–C bidomain of AmbB in three forms, the apo enzyme with disordered T domain, the holo form with serine linked phosphopantetheine (Ppant) and a holo form with substrate (l-alanine) loaded onto Ppant. …”
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Degradation of the electrical conductivity of charged domain walls in reduced lithium niobate crystals by Aleksandr M. Kislyuk, Tatiana S. Ilina, Ilya V. Kubasov, Dmitry A. Kiselev, Aleksandr A. Temirov, Andrei V. Turutin, Andrey S. Shportenko, Mikhail D. Malinkovich, Yuri N. Parkhomenko

“…In this work, the effect of long-term room temperature exposure on the electrical conductivity of the charged domain wall (CDWs) in nonpolar x-cut congruent lithium niobate (LiNbO3, LN) crystals has been studied. Bidomain ferroelectric structures containing head-to-head charged domain boundaries have been produced by diffusion annealing in air near the Curie temperature and by infrared annealing. …”
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