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101
3D Finite Element Electrical Model of Larval Zebrafish ECG Signals.
Published 2016-01-01“…Similarly, the electrical model consisted of two parts with the body described by Laplace's equation and the heart using a bidomain ionic model based upon the Fitzhugh-Nagumo equations. …”
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102
A Magnetoelectric Automotive Crankshaft Position Sensor
Published 2020-09-01“…The layered structure was made from a bidomain lithium niobate monocrystal with a Y + 128° cut and amorphous metal of Metglas. …”
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103
Parameter variations in personalized electrophysiological models of human heart ventricles.
Published 2021-01-01“…Ten cases of focal ventricular activation were simulated using the bidomain model and the TNNP 2006 cellular model. The population-based values of electrical conductivities and other model parameters were used for accuracy analysis, and their variations were used for sensitivity analysis. …”
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104
Electrocardiogram phenotypes in hypertrophic cardiomyopathy caused by distinct mechanisms: apico-basal repolarization gradients vs. Purkinje-myocardial coupling abnormalities
Published 2018“…High performance computing simulations using bidomain models were conducted to dissect key features explaining the ECG phenotypes with increased HCM Risk-SCD scores, namely Group 1A, characterized by normal QRS but inverted T waves laterally and coexistence of apical and septal hypertrophy; and Group 3 with marked QRS abnormalities (deep and wide S waves laterally) and septal hypertrophy. …”
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105
Human ventricular activation sequence and the simulation of the electrocardiographic QRS complex and its variability in healthy and intraventricular block conditions
Published 2016“…</p> <h4>Methods</h4> <p>Multiscale bidomain simulations using a detailed heart-torso human anatomical model are performed to investigate the impact of activation sequence characteristics on clinical QRS biomarkers. …”
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106
Enzyme-fusion strategies for redirecting and improving carotenoid synthesis in S. cerevisiae
Published 2019-06-01“…Synthetic genes encoding bidomain enzymes composed of CrtI and CrtB domains from the natural CrtYB fusion were connected in the two possible orientations, using natural and synthetic linkers. …”
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107
Chaste: A test-driven approach to software development for biological modelling
Published 2009“…Up to 16 Gigabytes (distributed across processors) for full resolution bidomain cardiac simulation. Classification: 3. External routines: Boost, CodeSynthesis XSD, CxxTest, HDF5, METIS, MPI, PETSc, Triangle, Xerces. …”
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108
Molecular–Statistical Theory for the Description of Re-Entrant Ferroelectric Phase
Published 2019-11-01“…We have shown that in the vicinity of Sm-<inline-formula> <math display="inline"> <semantics> <msubsup> <mi>C</mi> <mi>A</mi> <mo>*</mo> </msubsup> </semantics> </math> </inline-formula>−Sm-<inline-formula> <math display="inline"> <semantics> <msubsup> <mi>C</mi> <mi>re</mi> <mo>*</mo> </msubsup> </semantics> </math> </inline-formula> phase transition temperature, a very small electric field can cause a transition into the bidomain synclinic phase, where the helical pitch is unwound and the tilt planes have contributions either along or against the electric field. …”
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109
Structural elements of an NRPS cyclization domain and its intermodule docking domain
Published 2017“…To visualize the structure of a cyclization domain with an accompanying docking domain, we solved a 2.03-Å resolution structure of this bidomain EpoB unit, comprising residues M1-Q497 (62 kDa) of the 160-kDa EpoB protein. …”
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110
Functional Diversity and Engineering of the Adenylation Domains in Nonribosomal Peptide Synthetases
Published 2024-07-01“…On the basis of introducing the catalytic mechanism and multiple functions of the A domains, this article systematically describes several representative NRPS engineering strategies targeting the A domain, including mutagenesis of substrate-specificity codes, substitution of condensation-adenylation bidomains, the entire A domain or its subdomains, domain insertion, and whole-module rearrangements.…”
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111
Signaling by a bacterial phytochrome histidine kinase involves a conformational cascade reorganizing the dimeric photoreceptor
Published 2024-08-01“…Pr/Pfr comparisons show that bilin phototransformation alters PSM architecture culminating in a scissoring motion of the paired S-helices linking the PSMs to the HK bidomains that ends in reorientation of the paired catalytic ATPase modules relative to the phosphoacceptor histidines. …”
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