Showing 201 - 220 results of 2,702 for search '"bile acids"', query time: 0.11s Refine Results
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    Insulin alleviates murine colitis through microbiome alterations and bile acid metabolism by Shuying He, Jiating Li, Zirong Yao, Zixian Gao, Yonghong Jiang, Xueqing Chen, Liang Peng

    Published 2023-07-01
    “…Furthermore, LCA exerted anti-inflammatory effects by activating a G-protein-coupled bile acid receptor (TGR5), which inhibited the polarization of classically activated (M1) macrophages. …”
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    Farnesoid X receptor activation by bile acids suppresses lipid peroxidation and ferroptosis by Juliane Tschuck, Lea Theilacker, Ina Rothenaigner, Stefanie A. I. Weiß, Banu Akdogan, Van Thanh Lam, Constanze Müller, Roman Graf, Stefanie Brandner, Christian Pütz, Tamara Rieder, Philippe Schmitt-Kopplin, Michelle Vincendeau, Hans Zischka, Kenji Schorpp, Kamyar Hadian

    Published 2023-10-01
    “…We demonstrate that in liver cells with high FXR levels, knockout or inhibition of FXR sensitized cells to ferroptotic cell death, whereas activation of FXR by bile acids inhibited ferroptosis. Furthermore, FXR inhibited ferroptosis in ex vivo mouse hepatocytes and human hepatocytes differentiated from induced pluripotent stem cells. …”
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    Dynamics and determinants of human plasma bile acid profiles during dietary challenges by Jarlei Fiamoncini, Manuela J. Rist, Lara Frommherz, Pieter Giesbertz, Birgit Pfrang, Werner Kremer, Fritz Huber, Gabi Kastenmüller, Thomas Skurk, Hans Hauner, Karsten Suhre, Hannelore Daniel, Sabine E. Kulling

    Published 2022-07-01
    “…In recent years, bile acids (BA) have received great interest due to their pleiotropic biological activity and the presence of plasma membrane-bound and nuclear receptors. …”
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