Showing 221 - 240 results of 2,702 for search '"bile acids"', query time: 0.14s Refine Results
  1. 221

    The influence of biological sex and sex hormones on bile acid synthesis and cholesterol homeostasis by Taylor Phelps, Erin Snyder, Erin Rodriguez, Hailey Child, Pamela Harvey

    Published 2019-11-01
    “…However, recent debate surrounding their effectiveness and safety prompts consideration of alternative cholesterol-lowering therapies, including increasing cholesterol catabolism through bile acid (BA) synthesis. Targeting the enzymes that convert cholesterol to BAs represents a promising alternative to other cholesterol-lowering approaches that treat atherosclerosis as well as fatty liver diseases and diabetes mellitus. …”
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    Impaired Bile Acid Metabolism and Gut Dysbiosis in Mice Lacking Lysosomal Acid Lipase by Vinay Sachdev, Madalina Duta-Mare, Melanie Korbelius, Nemanja Vujić, Christina Leopold, Jan Freark de Boer, Silvia Rainer, Peter Fickert, Dagmar Kolb, Folkert Kuipers, Branislav Radovic, Gregor Gorkiewicz, Dagmar Kratky

    Published 2021-10-01
    “…These metabolic adaptations lead to impaired bile acid synthesis, lipoprotein uptake, and cholesterol absorption and ultimately to the resistance of LAL-KO mice to diet-induced obesity. …”
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    Systems Biology and Bile Acid Signalling in Microbiome-Host Interactions in the Cystic Fibrosis Lung by David F. Woods, Stephanie Flynn, Jose A. Caparrós-Martín, Stephen M. Stick, F. Jerry Reen, Fergal O’Gara

    Published 2021-06-01
    “…These bile acids are associated with inflammation and restructuring of the lung microbiota linked to chronicity. …”
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  20. 240

    Gut microbiota alters host bile acid metabolism to contribute to intrahepatic cholestasis of pregnancy by Bo Tang, Li Tang, Shengpeng Li, Shuang Liu, Jialin He, Pan Li, Sumin Wang, Min Yang, Longhui Zhang, Yuanyuan Lei, Dianji Tu, Xuefeng Tang, Hua Hu, Qin Ouyang, Xia Chen, Shiming Yang

    Published 2023-03-01
    “…Intrahepatic cholestasis of pregnancy (ICP) is a liver disease that sometimes develops during pregnancy and is characterized by increased serum bile acid levels. Here the authors report that the gut microbiome species B. fragilis is enriched in patients with ICP and promotes ICP development in mice via inhibition of signalling though the bile acid receptor FXR.…”
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