Alternative pathway of bile acid biosynthesis contributes to ameliorate NASH after induction of NAMPT/NAD+/SIRT1 axis by Na Yang, Runbin Sun, Xiaoli Zhang, Jing Wang, Lulu Wang, Huaijun Zhu, Man Yuan, Yifan Xu, Chun Ge, Jun He, Min Wang

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Effects of apical sodium-bile acid transporter inhibitor and obeticholic acid co-treatment in experimental non-alcoholic steatohepatitis by David J. Matye, Xuan Qin, Mohammad Nazmul Hasan, Lijie Gu, Yung Dai Clayton, Feng Li, Tiangang Li

Subjects: “…Bile acids…”
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Huangqi Decoction Alleviates Alpha-Naphthylisothiocyanate Induced Intrahepatic Cholestasis by Reversing Disordered Bile Acid and Glutathione Homeostasis in Mice by Jia-Sheng Wu, Yi-Fei Li, Yuan-Yuan Li, Yan Dai, Wen-Kai Li, Min Zheng, Zheng-Chun Shi, Rong Shi, Tian-Ming Wang, Bing-Liang Ma, Ping Liu, Yue-Ming Ma, Yue-Ming Ma

“…A metabolomics study revealed that the endogenous metabolites significantly affected by HQD were related to bile acid (BA) biosynthesis and glutathione metabolism pathways. …”
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Impact of Blueberry Consumption on the Human Fecal Bileacidome: A Pilot Study of Bile Acid Modulation by Freeze-Dried Blueberry by William Gagnon, Véronique Garneau, Jocelyn Trottier, Mélanie Verreault, Charles Couillard, Denis Roy, André Marette, Jean-Philippe Drouin-Chartier, Marie-Claude Vohl, Olivier Barbier

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Alterations in Circulating Bile Acids in Metabolic Dysfunction-Associated Steatotic Liver Disease: A Systematic Review and Meta-Analysis by Jiaming Lai, Ling Luo, Ting Zhou, Xiongcai Feng, Junzhao Ye, Bihui Zhong

Subjects: “…bile acid…”
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Ileal bile acid transporter inhibition in Cyp2c70 KO mice ameliorates cholestatic liver injury by Jennifer K. Truong, Ashley L. Bennett, Caroline Klindt, Ajay C. Donepudi, Sudarshan R. Malla, Kimberly J. Pachura, Alex Zaufel, Tarek Moustafa, Paul A. Dawson, Saul J. Karpen

“…Cyp2c70 is the liver enzyme in rodents responsible for synthesis of the primary 6-hydroxylated muricholate bile acid (BA) species. Cyp2c70 KO mice are devoid of protective, hydrophilic muricholic acids, leading to a more human-like BA composition and subsequent cholestatic liver injury. …”
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Trans-Anethole Alleviates DSS-Induced Ulcerative Colitis by Remodeling the Intestinal Flora to Regulate Immunity and Bile Acid Metabolism by Xu-Hui Li, Li Liu, Wen-Zhong Wu

“…We found that TA alleviates DSS-induced UC by remodeling the intestinal flora to regulate immunity and bile acid metabolism.…”
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Vine tea extract ameliorated acute liver injury by inhibiting hepatic autophagy and reversing abnormal bile acid metabolism by Ying Li, Ming-Wang Kong, Nan Jiang, Chen Ye, Xiao-Wei Yao, Xiao-Juan Zou, Hai-Ming Hu, Hong-Tao Liu

“…Gut microbiota disturbance, autophagy dysregulation, and accumulation of hepatic bile acids (BAs) are essential features of liver injury. …”
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Serum total bile acid levels assist in the prediction of acute intussusception with abdominal type Henoch-Schonlein purpura in children by Sijie Yu, Sijie Yu, Sijie Yu, Sijie Yu, Sijie Yu, Wei Feng, Wei Feng, Wei Feng, Wei Feng, Wei Feng, Yi Wang, Yi Wang, Yi Wang, Yi Wang, Yi Wang, Maoyuan Zhao, Maoyuan Zhao, Maoyuan Zhao, Maoyuan Zhao, Maoyuan Zhao, Yuying Tu, Yuying Tu, Zhenhua Guo, Zhenhua Guo, Zhenhua Guo, Zhenhua Guo, Zhenhua Guo, Zhenhua Guo, Zhenhua Guo

Subjects: “…total bile acid (TBA)…”
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Genetic deletion of hepatic NCOR1 protects from atherosclerosis by promoting alternative bile acid-metabolism and sterol excretion by Martin Geiger, Sara Oppi, Stefanie Nusser-Stein, Sarah Costantino, Shafeeq Ahmed Mohammed, Era Gorica, Joanne A. Hoogerland, Christian M. Matter, Ana T. Guillaumon, Frank Ruschitzka, Francesco Paneni, Maaike H. Oosterveer, Sokrates Stein

“…Besides assessing the progression of the disease in thoracoabdominal aortae en face, we analyzed hepatic cholesterol and bile acid metabolism at expression and functional levels. …”
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Identification and Distribution of Sterols, Bile Acids, and Acylcarnitines by LC–MS/MS in Humans, Mice, and Pigs—A Qualitative Analysis by Ambrin Farizah Babu, Ville Mikael Koistinen, Soile Turunen, Gloria Solano-Aguilar, Joseph F. Urban, Iman Zarei, Kati Hanhineva

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Circadian PER1 controls daily fat absorption with the regulation of PER1-PKA on phosphorylation of bile acid synthetase by Wenhao Ge, Qi Sun, Yunxia Yang, Zhao Ding, Junhao Liu, Jianfa Zhang

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Bile Acid-Related Regulation of Mucosal Inflammation and Intestinal Motility: From Pathogenesis to Therapeutic Application in IBD and Microscopic Colitis by Federica Di Vincenzo, Pierluigi Puca, Loris Riccardo Lopetuso, Valentina Petito, Letizia Masi, Bianca Bartocci, Marco Murgiano, Margherita De Felice, Lorenzo Petronio, Antonio Gasbarrini, Franco Scaldaferri

Subjects: “…bile acids…”
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Suppressive effect of Tripterygium hypoglaucum (Levl.) Hutch extract on rheumatoid arthritis in mice by modulating inflammasome and bile acid metabolism by Junping Zheng, Jianghui Hu, Yong Yang, Lei Xiong, Huabing Yang, Zhigang Zhang, Nan Jiang, Hongtao Liu

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Total glycosides contribute to the anti-diarrheal effects of Qiwei Baizhu Powder via regulating gut microbiota and bile acids by Guozhen Xie, Na Deng, Tao Zheng, Xinxin Peng, Shuihan Zhang, Zhoujin Tan

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Detection of bile acids in bronchoalveolar lavage fluid defines the inflammatory and microbial landscape of the lower airways in infants with cystic fibrosis by Jose A. Caparrós-Martín, Montserrat Saladie, S. Patricia Agudelo-Romero, F. Jerry Reen, Robert S. Ware, Peter D. Sly, Stephen M. Stick, Fergal O’Gara, on behalf of the COMBAT study group

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Inulin ameliorates metabolic syndrome in high-fat diet-fed mice by regulating gut microbiota and bile acid excretion by Shaoxiong Huang, Shiliang Dong, Lizhen Lin, Qiming Ma, Mengping Xu, Limei Ni, Qitong Fan

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Bile acids-mediated intracellular cholesterol transport promotes intestinal cholesterol absorption and NPC1L1 recycling by Jian Xiao, Le-Wei Dong, Shuai Liu, Fan-Hua Meng, Chang Xie, Xiao-Yi Lu, Weiping J. Zhang, Jie Luo, Bao-Liang Song

“…Here, we find that, in male mice, intracellular bile acids facilitate cholesterol transport to other organelles, such as endoplasmic reticulum, in a non-micellar fashion. …”
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Altered gut microbiota-host bile acid metabolism in IBS-D patients with liver depression and spleen deficiency pattern by Du, Liqing, Zhang, Zhaozhou, Zhai, Lixiang, Xu, Shujun, Yang, Wei, Huang, Chunhua, Lin, Chengyuan, Zhong, Linda Lidan, Bian, Zhaoxiang, Zhao, Ling

“…Background: Dysregulation of gut microbiota–host bile acid (BA) co-metabolism is a critical pathogenic factor of diarrhea-predominant irritable bowel syndrome (IBS-D). …”
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A prospective study of serum bile acid concentrations and colorectal cancer risk in post-menopausal women on the island of Guernsey. by Costarelli, V, Key, T, Appleby, P, Allen, D, Fentiman, I, Sanders, T

“…Serum bile acid concentrations reflect the faecal bile acid profile and may be of value as biomarkers of risk of colorectal cancer. …”