PHYSIOLOGY OF CHOLESTEROL METABOLISM (THE REVIEW) by YA. L. Tyuryumin, V. A. Shanturov, E. E. Tyuryumina

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Circulating oxylipin and bile acid profiles of dexmedetomidine, propofol, sevoflurane, and S-ketamine: a randomised controlled trial using tandem mass spectrometry by Aleksi Nummela, Lauri Laaksonen, Annalotta Scheinin, Kaike Kaisti, Tero Vahlberg, Mikko Neuvonen, Katja Valli, Antti Revonsuo, Markus Perola, Mikko Niemi, Harry Scheinin, Timo Laitio

Subjects: “…bile acids…”
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Dietary acetic acid suppress high-fat diet-induced obesity in mice by altering taurine conjugated bile acids metabolism by Rui Wang, Xiuqin Fan, Yuanyuan Lu, Dawei Chen, Yunfeng Zhao, Kemin Qi

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Phellodendronoside A Exerts Anticancer Effects Depending on Inducing Apoptosis Through ROS/Nrf2/Notch Pathway and Modulating Metabolite Profiles in Hepatocellular Carcinoma by Si Y, Hui C, Guo T, Liu M, Chen X, Dong C, Feng S

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Metabolomics and Lipidomics Study Unveils the Impact of Tauroursodeoxycholic Acid on Hyperlipidemic Mice by Na Cui, Wensen Zhang, Fazhi Su, Zhihong Zhang, Weijie Qiao, Yanping Sun, Bingyou Yang, Haixue Kuang, Qiuhong Wang

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Catalpol protects hepatopulmonary syndrome rats against liver and lung injury by ZENG Ziyang, LEI Yuhao, WU Xianfeng

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Discovery of BAR502, as potent steroidal antagonist of leukemia inhibitory factor receptor for the treatment of pancreatic adenocarcinoma by Cristina Di Giorgio, Rachele Bellini, Antonio Lupia, Antonio Lupia, Carmen Massa, Martina Bordoni, Silvia Marchianò, Rosalinda Rosselli, Valentina Sepe, Pasquale Rapacciuolo, Federica Moraca, Federica Moraca, Elva Morretta, Patrizia Ricci, Ginevra Urbani, Maria Chiara Monti, Michele Biagioli, Eleonora Distrutti, Bruno Catalanotti, Angela Zampella, Stefano Fiorucci

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Rats with high aerobic capacity display enhanced transcriptional adaptability and upregulation of bile acid metabolism in response to an acute high‐fat diet by Harrison D. Stierwalt, E. Matthew Morris, Adrianna Maurer, Udayan Apte, Kathryn Phillips, Tiangang Li, Grace M. E. Meers, Lauren G. Koch, Steven L. Britton, Greg Graf, R. Scott Rector, Kelly Mercer, Kartik Shankar, John P. Thyfault

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In vitro antioxidant, anti-glycation, and bile acid-lowering capacity of peanut milk fermented with Lactiplantibacillus plantarum Kinko-SU4 by Mahiro Yamamoto, Natsumi Handa, Ayaka Nakamura, Hajime Takahashi, Takashi Kuda

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Bacteroides uniformis-induced perturbations in colonic microbiota and bile acid levels inhibit TH17 differentiation and ameliorate colitis developments by YiTing Yan, Yu Lei, Ying Qu, Zhen Fan, Ting Zhang, Yangbin Xu, Qian Du, Daniel Brugger, Yulin Chen, Ke Zhang, Enping Zhang

“…Our findings suggest that Bu or bile acid supplements are potential therapies for colitis and other diseases associated with intestinal barrier dysfunction.…”
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Semi-Targeted Profiling of Bile Acids by High-Resolution Mass Spectrometry in a Rat Model of Drug-Induced Liver Injury by Myriam Mireault, Vivaldy Prinville, Leanne Ohlund, Lekha Sleno

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Bile acids at neutral and acidic pH induce apoptosis and gene cleavages in nasopharyngeal epithelial cells: implications in chromosome rearrangement by Sang-Nee Tan, Sai-Peng Sim

“…Abstract Background Chronic rhinosinusitis (CRS) increases the risk of developing nasopharyngeal carcinoma (NPC) while nasopharyngeal reflux is known to be one of the major aetiological factors of CRS. Bile acid (BA), the component of gastric duodenal contents, has been recognised as a carcinogen. …”
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Sulfation of chondroitin and bile acids converges to antagonize Wnt/β-catenin signaling and inhibit APC deficiency-induced gut tumorigenesis by Pengfei Xu, Yue Xi, Jong-Won Kim, Junjie Zhu, Min Zhang, Meishu Xu, Songrong Ren, Da Yang, Xiaochao Ma, Wen Xie

“…In summary, we have uncovered the protective role of PAPSS2-mediated chondroitin sulfation and bile acids–FXR–TLE3 activation in the prevention of gut carcinogenesis via the antagonization of Wnt/β-catenin signaling. …”
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Dietary soybean protein ameliorates high-fat diet-induced obesity by modifying the gut microbiota-dependent biotransformation of bile acids. by Keita Watanabe, Miki Igarashi, Xuan Li, Akiho Nakatani, Junki Miyamoto, Yuka Inaba, Asuka Sutou, Tsutomu Saito, Takumi Sato, Nobuhiko Tachibana, Hiroshi Inoue, Ikuo Kimura

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Placental exosomal level of alanine aminotransferase is more accurate predictive biomarker of intrahepatic cholestasis of pregnancy than total bile acid by Sahaya Ravichandran, Rupa Karunanithi

“…Plancental exosomes were isolated to determine the exosomal levels of alanine aminotransferase (ALT) and total bile acid (TBA). The predictive values of placental exosomal TBA and ALT were determined using receiver operating characteristic (ROC) curve analysis. …”
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Parabacteroides distasonis ameliorates hepatic fibrosis potentially via modulating intestinal bile acid metabolism and hepatocyte pyroptosis in male mice by Qi Zhao, Man-Yun Dai, Ruo-Yue Huang, Jing-Yi Duan, Ting Zhang, Wei-Min Bao, Jing-Yi Zhang, Shao-Qiang Gui, Shu-Min Xia, Cong-Ting Dai, Ying-Mei Tang, Frank J. Gonzalez, Fei Li

“…Here the authors report that P. distasonis ameliorates liver fibrosis in studies with male mice, potentially via altered bile acid metabolism and hepatocyte pyroptosis.…”
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Functional recovery outcomes following acute stroke is associated with abundance of gut microbiota related to inflammation, butyrate and secondary bile acid by Tyler C. Hammond, Tyler C. Hammond, Elizabeth Powell, Stefan J. Green, George Chlipala, Jacqueline Frank, Jacqueline Frank, Andrew T. Yackzan, Lucille M. Yanckello, Lucille M. Yanckello, Ya-Hsuan Chang, Ya-Hsuan Chang, Xin Xing, Xin Xing, Sally Heil, Joe E. Springer, Joe E. Springer, Keith Pennypacker, Keith Pennypacker, Arnold Stromberg, Lumy Sawaki, Ai-Ling Lin, Ai-Ling Lin, Ai-Ling Lin

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PNPLA3 allele frequency has no impact on biliary bile acid composition or disease course in patients with primary sclerosing cholangitis. by Martti Färkkilä, Hannu Kautiainen, Andrea Tenca, Kalle Jokelainen, Johanna Arola

“…Furthermore, we analyzed the impact of PNPLA3 on phospholipid and bile acid composition to evaluate the effect of the PNPLA3 status on UDCA response.…”
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Synergistic effect of Euphorbia kansui stir-fried with vinegar and bile acids on malignant ascites effusion through modulation of gut microbiota by Shengyun Dai, Shikang Zhou, Yonghui Ju, Weifeng Yao, Yuping Tang, Jian Zheng, Shuangcheng Ma, Yi Zhang, Li Zhang

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Redundant Functions of ERK1 and ERK2 Maintain Mouse Liver Homeostasis Through Down‐Regulation of Bile Acid Synthesis by Francesca Cingolani, Yunshan Liu, Yang Shen, Jing Wen, Alton B. Farris, Mark J. Czaja

“…Elevated bile acids were the mechanism of liver injury, as bile acid reduction by SC‐435, an inhibitor of the ileal apical sodium–dependent bile acid transporter, prevented liver injury. …”
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