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841
Mogrol stimulates G-protein-coupled bile acid receptor 1 (GPBAR1/TGR5) and insulin secretion from pancreatic β-cells and alleviates hyperglycemia in mice
Published 2024-02-01“…Here, we identified the G-protein-coupled bile acid receptor 1 (GPBAR1, also known as TGR5) as a target of the triterpenoid mogrol, a class of aglycone mogroside derivative from Siraitia grosvenorii. …”
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842
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843
The ratio of 12α to non-12-hydroxylated bile acids reflects hepatic triacylglycerol accumulation in high-fat diet-fed C57BL/6J mice
Published 2022-10-01“…Abstract In our previous study, enterohepatic 12α-hydroxylated (12α) bile acid (BA) levels were found to be correlated with hepatic triacylglycerol concentration in rats fed high-fat (HF) diet. …”
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844
Total <i>Sn</i>-2 Palmitic Triacylglycerols and the Ratio of OPL to OPO in Human Milk Fat Substitute Modulated Bile Acid Metabolism and Intestinal Microbiota Composition in Rats
Published 2023-11-01“…In this study, the impact of <i>sn</i>-2 palmitic triacyclglycerols (TAGs) in combination with their ratio of two major TAGs (1-oleoyl-2-palmitoyl-3-linoleoylglycerol (OPL) to 1,3-dioleoyl-2-palmitoylglycerol (OPO)) in human milk fat substitute (HMFS) on bile acid (BA) metabolism and intestinal microbiota composition was investigated in newly-weaned Sprague–Dawley rats after four weeks of high-fat feeding. …”
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845
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846
Metabolic Soft Spot and Pharmacokinetics: Functionalization of C-3 Position of an Eph–Ephrin Antagonist Featuring a Bile Acid Core as an Effective Strategy to Obtain Oral Bioavailability in Mice
Published 2021-12-01“…UniPR129, an L-β-homotryptophan conjugate of the secondary bile acid lithocholic acid (LCA), acts as an effective protein-protein interaction (PPI) inhibitor of the Eph–ephrin system but suffers from a poor oral bioavailability in mice. …”
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847
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848
An impaired pituitary–adrenal signalling axis in stable cirrhosis is linked to worse prognosis
Published 2023-08-01Subjects: Get full text
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849
Circadian Rhythms Coordinated With Gut Microbiota Partially Account for Individual Differences in Hepatitis B-Related Cirrhosis
Published 2022-07-01Subjects: Get full text
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850
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851
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852
Metabolomic signatures of intestinal colonization resistance against Campylobacter jejuni in mice
Published 2023-12-01Subjects: Get full text
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853
Gut microbiota, metabolites, and cardiovascular diseases
Published 2021-01-01Subjects: “…bile acids; cardiovascular diseases; gut microbiome; short-chain fatty acids; trimethylamine…”
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854
Bacteroides vulgatus Ameliorates Lipid Metabolic Disorders and Modulates Gut Microbial Composition in Hyperlipidemic Rats
Published 2023-02-01Subjects: Get full text
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855
Enhanced Bilosomal Properties Resulted in Optimum Pharmacological Effects by Increased Acidification Pathways
Published 2021-07-01Subjects: “…bile acids…”
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856
Mechanism-based target therapy in primary biliary cholangitis: opportunities before liver cirrhosis?
Published 2023-05-01Subjects: Get full text
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857
Gradual dosing of ursodeoxycholic acid in mothers with intrahepatic cholestasis of pregnancy may improve composite neonatal outcome
Published 2024-05-01Subjects: Get full text
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858
Pharmacological and Advanced Cell Respiration Effects, Enhanced by Toxic Human-Bile Nano-Pharmaceuticals of Probucol Cell-Targeting Formulations
Published 2020-07-01Subjects: “…bile acids…”
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859
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860
A Metabolite Perspective on the Involvement of the Gut Microbiota in Type 2 Diabetes
Published 2023-10-01Subjects: Get full text
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