Effect of calcium carbonate and aluminum hydroxide on human intestinal function. by Saunders, D, Sillery, J, Chapman, R

“…These observations help to explain how these two antacids may lower blood lipids and ameliorate the effects of fecal bile acids and fatty acids on colonic mucosa.…”

The Role of Bifidobacterium SPP. on Cholestrol Assimilation in the in Vitro and in Vivo Studies by Sabet, Maryam Rezaei

“…Likewise in overall the percentage of deconjugation activity was higher in TPY medium supplemented with 5mM bile acids (P<0.05) compared to the TPY broth with 10mM bile acids. …”
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Untargeted lipidomics and metagenomics reveal the mechanism of aspirin eugenol ester relieving hyperlipidemia in ApoE−/− mice by Xiao-Rong Lu, Xi-Wang Liu, Shi-Hong Li, Zhe Qin, Li-Xia Bai, Wen-Bo Ge, Jian-Yong Li, Ya-Jun Yang

“…In conclusion, these results suggested that the effect of AEE on hyperlipidemia was closely related to the gut microbiota by the change of bile acids and liver lipids.…”
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Mitochondrial impairment induced by chenodeoxycholic acid: The protective effect of taurine and carnosine supplementation by Reza Heidari, Narges Abdoli, Mohammad Mehdi Ommati, Akram Jamshidzadeh, Hossein Niknahad

“…Chenodeoxycholic acid (CDCA) is a toxic hydrophobic bile acid. Oxidative stress and mitochondrial dysfunction are well-known mechanisms of bile acids cytotoxicity. …”
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ASSOCIATION OF INTESTINAL BACTERIAL OVERGROWTH AND DISEASES OF HEPATOBIARY TRACT by Ya. M. Vakhrushev, A. P. Lukashevich, E. V. Suchkova

“…Intestinal dysbiosis was determined by plating feces on nutrient media. Bile acids in bile were determined on the AmazonX mass spectrometer (Bruker Daltonik GmbH, Bremen, Germany). …”
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The role of intestinal microflora in the development of cholelithiasis (literature review) by N. A. Hohlacheva, N. N. Glazyrina, A. P. Lukashevich, Ja. M. Vahrushev, T. S. Kosareva

“…Secondly, the role of dysbiosis in violation of enterohepatic circulation of bile acids is essential. The change in the ratio of conjugated and deconjugated bile acids contributes to the formation of lithogenic bile. …”
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Emerging role of the crosstalk between gut microbiota and liver metabolome of subterranean herbivores in response to toxic plants by Yuchen Tan, Baohui Yao, Yukun Kang, Shangli Shi, Zunji Shi, Junhu Su

“…Of note, the microbial taxa Veillonella in the -SCG group was significantly correlated with liver inflammation markers, while Clostridium innocum in the +SCG group had a significant positive correlation with secondary bile acids. The increase in bile acids and PGs can lead to liver inflammatory reactions, suggesting that +SCG plateau zokors may mitigate the toxicity of SC plants by reducing liver inflammatory markers including PGs and secondary bile acids, thereby avoiding liver damage. …”
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Effects of Bifidobacterium Pseudocatenulatum G4 on Clostridium Scindens and Clostridium Hiranonis by Rasti, Babak

“…The percentage of deconjugation activity was higher in TPY medium supplemented with 0.25mM bile acids compared to TPY broth with 5.0mM bile acids. …”
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Gut microbiota in dementia with Lewy bodies by Hiroshi Nishiwaki, Jun Ueyama, Kenichi Kashihara, Mikako Ito, Tomonari Hamaguchi, Tetsuya Maeda, Yoshio Tsuboi, Masahisa Katsuno, Masaaki Hirayama, Kinji Ohno

“…As Ruminococcus torques and Collinsella are also major secondary bile acids-producing bacteria, we quantified fecal bile acids and found that the production of ursodeoxycholic acid (UDCA) was high in DLB. …”
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Replacing saturated fatty acids with polyunsaturated fatty acids increases the abundance of Lachnospiraceae and is associated with reduced total cholesterol levels—a randomized con... by Vibeke H. Telle-Hansen, Line Gaundal, Nasser Bastani, Ida Rud, Marte G. Byfuglien, Terje Gjøvaag, Kjetil Retterstøl, Kirsten B. Holven, Stine M. Ulven, Mari C. W. Myhrstad

“…The aim of the present study was to investigate the effect of dietary fat quality on gut microbiota, short-chain fatty acids (SCFAs), and bile acids in healthy individuals. In addition, to investigate how changes in gut microbiota correlate with blood lipids, bile acids, and fatty acids. …”
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Effect of Addition of Methionine to Rice Protein on the Cholesterol and Lipoproteins Concentrations in Rats by Jaefar Dhahir, Jaber Dhahir, Qassem Al-Awwad

“…The concentration of liver cholesterol was also lower in rats fed the RP diet.The serum high density lipoprotein (HDL) cholesterol level and fecal bile acids were higher in rats fed (RP) diet than in those fed (C) or RPM diets.These results indicated that increased fecal bile acids excretion may be responsible for the antihypercholesterolemic effect of rice protein compared with casein.…”
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Genetics in Familial Intrahepatic Cholestasis: Clinical Patterns and Development of Liver and Biliary Cancers: A Review of the Literature by Giovanni Vitale, Alessandro Mattiaccio, Amalia Conti, Laura Turco, Marco Seri, Fabio Piscaglia, Maria Cristina Morelli

“…Mutations in FIC genes can influence serum and hepatic levels of bile acids. Experimental studies on the <i>NR1H4</i> gene have shown that high bile acids concentrations cause excessive production of inflammatory cytokines, resistance to apoptosis, and increased cell regeneration, all risk conditions for developing hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA). …”
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Paeoniae Radix Rubra can enhance fatty acid β-oxidation and alleviate gut microbiota disorder in α-naphthyl isothiocyanate induced cholestatic model rats by Jing-Jing Xu, Feng Xu, Wei Wang, Peng-Pu Wang, Jing Xian, Xing Han, Ming-Ying Shang, Guang-Xue Liu, Xuan Wang, Shao-Qing Cai

“…As the relative abundance of these eight genera was significantly correlated with the levels of the five secondary bile acids (deoxycholic acid, taurolithocholic acid, etc.) reduced by PRR, and Bacteroides and Escherichia were reported to promote the production of secondary bile acid, we inferred that the downregulation of PRR on five secondary bile acids in model rats was inseparable from gut microbiota. …”
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Protein Phosphatase 1 Regulatory Subunit 3B Genotype at rs4240624 Has a Major Effect on Gallbladder Bile Composition by Ville Männistö, Dorota Kaminska, Pirjo Käkelä, Mikko Neuvonen, Mikko Niemi, Marcus Alvarez, Päivi Pajukanta, Stefano Romeo, Max Nieuwdorp, Albert.K. Groen, Jussi Pihlajamäki

“…We analyzed the effect of PPP1R3B rs4240624 variant on bile acid composition in individuals with obesity. …”
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The Role of Inflammation in Cholestatic Liver Injury by Chen J, Zhang S

“…These cells, stimulated by a variety of factors such as bile acids, inflammatory chemokines, and complement, can be activated and accumulate in the cholestatic liver, and with the involvement of inflammatory mediators and modulation by cytokines, can lead to destruction of hepatocytes and bile duct epithelial cells and exacerbate (and occasionally retard) the progression of cholestatic liver disease. …”
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Treatment of primary sclerosing cholangitis combined with inflammatory bowel disease by You Sun Kim, Edward H. Hurley, Yoojeong Park, Sungjin Ko

“…Potential candidate drugs have been developed based on the pathogenesis of PSC-IBD, such as those that target modulation of bile acids, inflammation, fibrosis, and gut dysbiosis. …”
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Serum metabolome changes in adult patients with severe dengue in the critical and recovery phases of dengue infection by Cui, Liang, Pang, Junxiong, Lee, Yie Hou, Ooi, Eng Eong, Ong, Choon Nam, Leo, Yee Sin, Tannenbaum, Steven R

“…There were 29 differentially expressed metabolites identified between DF and DHF at the critical phase. These include bile acids, purines, acylcarnitines, phospholipids, and amino acids. …”
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Surgical correction of a splenophrenic shunt in a dog: a case report by H. Yoon, M. Roh, S. Jeong

“…Preprandial and postprandial bile acids levels were still elevated 10 months after surgery. …”
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The gut signals to AGRP-expressing cells of the pituitary to control glucose homeostasis by Shun-Mei Liu, Bruno Ifebi, Fred Johnson, Alison Xu, Jacquelin Ho, Yunlei Yang, Gary Schwartz, Young Hwan Jo, Streamson Chua Jr.

“…One of these Agrp promoters/enhancers, Agrp-B, is regulated by bile acids. We generated an Agrp-B knockin FLP/knockout allele. …”
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Obeticholic Acid and Insulin Sensitivity in Overweight Patients with Prediabetes by H. Amer, M. Nesim, H. Mansour, E. Nasr, N. Ahmed

“…The byproducts of the breakdown of cholesterol are bile acids, which are crucial for preserving cholesterol homeostasis. …”
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