The peculiarities of the functional state of the liver under conditions of skeletal trauma, thermal burns of the skin and their combinations in the period of later manifestations o... by T. V. Kashchak, T. I. Dzetsiukh, U. V. Uhlyar

“…In the obtained bile was determined by the concentration of total bile acids, cholesterol, conjugated bilirubin. The cholate-cholesterol coefficient and the degree of conjugation of bilirubin were calculated. …”
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Optimisation of bile production during normothermic preservation of porcine livers. by Imber, C, St Peter, S, de Cenarruzabeitia, I, Lemonde, H, Rees, M, Butler, A, Clayton, P, Friend, P

“…It was shown that all three native pig bile acids were decreased to 30% of their original value by 20 h of unsupplemented perfusion. …”

Influences of a-tocopherol on cholesterol metabolism and fatty streak development in apolipoprotein E-deficient mice fed an atherogenic diet by Peluzio M.C.G., Homem A.P.P., Cesar G.C., Azevedo G.S., Amorim R., Cara D.C., Saliba H., Vieira E.C., Arantes R.E., Alvarez-Leite J.

“…Total cholesterol in serum and liver and 3-OH-alpha-sterols in feces, and fecal excretion of bile acids were determined and histological analyses of aortic lesion were performed. …”
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Effect of Metadoxine on Chronic Primary Hepatopathies in Canines:  Number of Cases by Paula María Bermúdez-Duarte, José Alfredo Rivera-Rojas

“…A decrease in the occurrence of vomiting and anorexia was observed (p=0.03), a non-significant increase in ALT and ALP (p=0.84; p=0.43), a reduction in bile acids (p=0.4), and no change in ultrasound score (p=0.42) or histopathological diagnosis (p>0.05). …”
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Low-dose biliatresone treatment of pregnant mice causes subclinical biliary disease in their offspring: Evidence for a spectrum of neonatal injury. by Kapish Gupta, Jimmy P Xu, Tamir Diamond, Iris E M de Jong, Andrew Glass, Jessica Llewellyn, Neil D Theise, Orith Waisbourd-Zinman, Jeffrey D Winkler, Edward M Behrens, Clementina Mesaros, Rebecca G Wells

“…However, serum levels of glycocholic acid were elevated at P5, suggesting altered bile metabolism, and the serum bile acid profile became increasingly abnormal through P21, with enhanced glycine conjugation of bile acids. …”
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The role of intestinal microbes on intestinal barrier function and host immunity from a metabolite perspective by Yifeng Fu, Yifeng Fu, Jin Lyu, Shuangshuang Wang

“…For example, metabolites like short-chain fatty acids (SCFA) and secondary bile acids can release inflammatory-mediated signals by binding to specific receptors. …”
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Efektivitas Ekstrak Daun Annona Muricata Terhadap Penurunan Kolesterol Total Pada Lansia Dengan Hiperkolesterolemia Di Panti Werdha Mojopahit Mojokerto by Muhammad Al Amin, ainun najib, ali syahbana

“…Saponins can bind with bile acids, which in turn will reduce the enterohepatic circulation of bile acids and cause an increase in the process of excretion of cholesterol.…”
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Hypocholesterolaemic effect of yoghurt containing Bifidobacterium pseudocatenulatum G4 or Bifidobacterium longum BB536 by Al-Sheraji, Sadeq Hasan, Ismail, Amin, Abd Manap, Mohd Yazid, Mustafa, Shuhaimi, Mohd Yusof, Rokiah, Hassan, Fouad Abdulrahman

“…The effect of a yoghurt supplement containing Bifidobacterium pseudocatenulatum G4 or Bifidobacterium longum BB536 on plasma lipids, lipid peroxidation and the faecal excretion of bile acids was examined in rats fed a cholesterol-enriched diet. …”
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Alterations in Microbiota and Metabolites Related to Spontaneous Diabetes and Pre-Diabetes in Rhesus Macaques by Cong Jiang, Xuan Pan, Jinxia Luo, Xu Liu, Lin Zhang, Yun Liu, Guanglun Lei, Gang Hu, Jing Li

“…The DMs were significantly enriched in the bile acids metabolism, fatty acids metabolism and amino acids metabolism pathways. …”
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Apolipoprotein M regulates the orphan nuclear receptor LRH-1 gene expression through binding to its promoter region in HepG2 cells by Pan Y, Zhou HG, Zhou H, Hu M, Tang LJ

“…In conclusion, our findings present supportive evidence that ApoM is a regulator of human LRH-1 transcription, and further reveal the importance of ApoM as a critical regulator of bile acids metabolism. Keywords: bile acids, chromatin immunoprecipitation assay, farnesoid X receptor, GW4064, high-density lipoprotein …”
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Congenital gallbladder agenesis in a 9-month-old Bull Terrier by O Gojska-Zygner, M Galanty, B Degorska, J Frymus, W Zygner

“…After nine weeks of therapy, the dog was in good condition, the diarrhoea and vomiting ceased, and the liver function parameters, such as the AST and GLDH activities, and the concentration of bile acids had decreased to reference intervals.…”
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THE MECHANISMS OF THE DISORDERS OF MOTOR-EVACUATION FUNCTION OF GALL BLADDER AND THEIR IMPORTANCE IN THE DEVELOPMENT OF CHOLELITHIASIS by Ya. M. Vakhrushev, N. A. Khokhlacheva, P. S. Mikheevа, E. V. Suchkova

“…The study of the biochemical  composition revealed an increase in cholesterol, a decrease in bile  acids and a cholate-cholesterol coefficient in portions B and C of bile. …”
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Taurocholic Acid and Glycocholic Acid Inhibit Inflammation and Activate Farnesoid X Receptor Expression in LPS-Stimulated Zebrafish and Macrophages by Xutao Ge, Shaoze Huang, Can Ren, Lu Zhao

“…Combined with high-resolution mass spectrometry, transgenic zebrafish-based phenotypic screening, and mouse macrophage models, taurochiolic acid (TCA) and glycoholic acid (GCA) were identified as two naturally derived anti-inflammatory agents with high efficacy and safety. Both bile acids significantly inhibited the lipopolysaccharide-induced macrophage recruitment and the secretion of proinflammatory cytokines/chemokines in in vivo and in vitro models. …”
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Minocycline-induced disruption of the intestinal FXR/FGF15 axis impairs osteogenesis in mice by Matthew D. Carson, Amy J. Warner, Jessica D. Hathaway-Schrader, Vincenza L. Geiser, Joseph Kim, Joy E. Gerasco, William D. Hill, John J. Lemasters, Alexander V. Alekseyenko, Yongren Wu, Hai Yao, J. Ignacio Aguirre, Caroline Westwater, Chad M. Novince

“…This work introduces bile acids as a potentially novel mediator of gut/liver signaling actions contributing to gut microbiota effects on bone.…”
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Aryl Hydrocarbon Receptor (AhR) Activation by 2,3,7,8-Tetrachlorodibenzo-<i>p</i>-Dioxin (TCDD) Dose-Dependently Shifts the Gut Microbiome Consistent with the Progression of Non-Al... by Russell R. Fling, Timothy R. Zacharewski

“…TCDD induces hepatic fat accumulation and increases levels of secondary bile acids, including taurolithocholic acid and deoxycholic acid (microbial modified bile acids involved in host bile acid regulation signaling pathways). …”
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The use of metformin in the treatment of Intrahepatic cholestasis of pregnancy by Paulina Pawłowska, Alicja Ozga-Stachurska, Justyna Wójcik-Grudzień, Martyna Rozenbajgier

“…In these patients, the levels of bile acids and liver enzymes decreased after the use of metformin. …”
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Dietary fat and bile juice, but not obesity, are responsible for the increase in small intestinal permeability induced through the suppression of tight junction protein expression... by Suzuki Takuya, Hara Hiroshi

“…Glucose tolerance, intestinal permeability, intestinal tight junction (TJ) proteins expression, plasma bile acids concentration were evaluated. In addition, the effects of rat bile juice and dietary fat, possible mediators of the increase in the intestinal permeability in the obesity, on TJ permeability were explored in human intestinal Caco-2 cells.…”
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Evaluation of clinical outcomes in children with intrahepatic cholestasis postpartial external biliary diversion: A single-center experience by Hadeer Mohamed Nasr El-Din, Noha Adel Yassin, Nehal M EL Koofy, Alaa Obeida, Sherif Nabhan Kaddah, Gamal Hassan Eltagy, Wesam Mohamed

“…A significant improvement was detected in the 5-D itching score (p-value < 0.001), PedsQL (p-value < 0.001), and bile acids level (p-value 0.013). The preexisting growth failure was ameliorated. …”
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Gut Microbiota Composition and Metabolites as the new Determinants of Cardiovascular Pathology Development by O. M. Drapkina, A. N. Kaburova

“…In the majority of research SCFA and secondary bile acids have demonstrated protective role in CVD. …”
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Supplementing a specific synbiotic suppressed the incidence of AOM/DSS-induced colorectal cancer in mice by Huixia Wu, Zhengchun Wu, Yilan Qiu, Fangjian Zhao, Minjing Liao, Zhihong Zhong, Jian Chen, Yiliang Zeng, Rushi Liu

“…Moreover, the synbiotic significantly improved the disorder of the colonic microbiota of CAC mice, promoted the formation of SCFAs and the production of secondary bile acids, and alleviated the accumulation of primary bile acids in the CAC mice. …”
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