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1201
The peculiarities of the functional state of the liver under conditions of skeletal trauma, thermal burns of the skin and their combinations in the period of later manifestations o...
Published 2019-08-01“…In the obtained bile was determined by the concentration of total bile acids, cholesterol, conjugated bilirubin. The cholate-cholesterol coefficient and the degree of conjugation of bilirubin were calculated. …”
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1202
Optimisation of bile production during normothermic preservation of porcine livers.
Published 2002“…It was shown that all three native pig bile acids were decreased to 30% of their original value by 20 h of unsupplemented perfusion. …”
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1203
Influences of a-tocopherol on cholesterol metabolism and fatty streak development in apolipoprotein E-deficient mice fed an atherogenic diet
Published 2001-01-01“…Total cholesterol in serum and liver and 3-OH-alpha-sterols in feces, and fecal excretion of bile acids were determined and histological analyses of aortic lesion were performed. …”
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1204
Effect of Metadoxine on Chronic Primary Hepatopathies in Canines: Number of Cases
Published 2023-09-01“…A decrease in the occurrence of vomiting and anorexia was observed (p=0.03), a non-significant increase in ALT and ALP (p=0.84; p=0.43), a reduction in bile acids (p=0.4), and no change in ultrasound score (p=0.42) or histopathological diagnosis (p>0.05). …”
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1205
Low-dose biliatresone treatment of pregnant mice causes subclinical biliary disease in their offspring: Evidence for a spectrum of neonatal injury.
Published 2024-01-01“…However, serum levels of glycocholic acid were elevated at P5, suggesting altered bile metabolism, and the serum bile acid profile became increasingly abnormal through P21, with enhanced glycine conjugation of bile acids. …”
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1206
The role of intestinal microbes on intestinal barrier function and host immunity from a metabolite perspective
Published 2023-10-01“…For example, metabolites like short-chain fatty acids (SCFA) and secondary bile acids can release inflammatory-mediated signals by binding to specific receptors. …”
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1207
Efektivitas Ekstrak Daun Annona Muricata Terhadap Penurunan Kolesterol Total Pada Lansia Dengan Hiperkolesterolemia Di Panti Werdha Mojopahit Mojokerto
Published 2023-06-01“…Saponins can bind with bile acids, which in turn will reduce the enterohepatic circulation of bile acids and cause an increase in the process of excretion of cholesterol.…”
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1208
Hypocholesterolaemic effect of yoghurt containing Bifidobacterium pseudocatenulatum G4 or Bifidobacterium longum BB536
Published 2012“…The effect of a yoghurt supplement containing Bifidobacterium pseudocatenulatum G4 or Bifidobacterium longum BB536 on plasma lipids, lipid peroxidation and the faecal excretion of bile acids was examined in rats fed a cholesterol-enriched diet. …”
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1209
Alterations in Microbiota and Metabolites Related to Spontaneous Diabetes and Pre-Diabetes in Rhesus Macaques
Published 2022-08-01“…The DMs were significantly enriched in the bile acids metabolism, fatty acids metabolism and amino acids metabolism pathways. …”
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1210
Apolipoprotein M regulates the orphan nuclear receptor LRH-1 gene expression through binding to its promoter region in HepG2 cells
Published 2015-04-01“…In conclusion, our findings present supportive evidence that ApoM is a regulator of human LRH-1 transcription, and further reveal the importance of ApoM as a critical regulator of bile acids metabolism. Keywords: bile acids, chromatin immunoprecipitation assay, farnesoid X receptor, GW4064, high-density lipoprotein …”
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1211
Congenital gallbladder agenesis in a 9-month-old Bull Terrier
Published 2021-07-01“…After nine weeks of therapy, the dog was in good condition, the diarrhoea and vomiting ceased, and the liver function parameters, such as the AST and GLDH activities, and the concentration of bile acids had decreased to reference intervals.…”
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1212
THE MECHANISMS OF THE DISORDERS OF MOTOR-EVACUATION FUNCTION OF GALL BLADDER AND THEIR IMPORTANCE IN THE DEVELOPMENT OF CHOLELITHIASIS
Published 2018-02-01“…The study of the biochemical composition revealed an increase in cholesterol, a decrease in bile acids and a cholate-cholesterol coefficient in portions B and C of bile. …”
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1213
Taurocholic Acid and Glycocholic Acid Inhibit Inflammation and Activate Farnesoid X Receptor Expression in LPS-Stimulated Zebrafish and Macrophages
Published 2023-02-01“…Combined with high-resolution mass spectrometry, transgenic zebrafish-based phenotypic screening, and mouse macrophage models, taurochiolic acid (TCA) and glycoholic acid (GCA) were identified as two naturally derived anti-inflammatory agents with high efficacy and safety. Both bile acids significantly inhibited the lipopolysaccharide-induced macrophage recruitment and the secretion of proinflammatory cytokines/chemokines in in vivo and in vitro models. …”
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1214
Minocycline-induced disruption of the intestinal FXR/FGF15 axis impairs osteogenesis in mice
Published 2023-01-01“…This work introduces bile acids as a potentially novel mediator of gut/liver signaling actions contributing to gut microbiota effects on bone.…”
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1215
Aryl Hydrocarbon Receptor (AhR) Activation by 2,3,7,8-Tetrachlorodibenzo-<i>p</i>-Dioxin (TCDD) Dose-Dependently Shifts the Gut Microbiome Consistent with the Progression of Non-Al...
Published 2021-11-01“…TCDD induces hepatic fat accumulation and increases levels of secondary bile acids, including taurolithocholic acid and deoxycholic acid (microbial modified bile acids involved in host bile acid regulation signaling pathways). …”
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1216
The use of metformin in the treatment of Intrahepatic cholestasis of pregnancy
Published 2022-09-01“…In these patients, the levels of bile acids and liver enzymes decreased after the use of metformin. …”
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1217
Dietary fat and bile juice, but not obesity, are responsible for the increase in small intestinal permeability induced through the suppression of tight junction protein expression...
Published 2010-03-01“…Glucose tolerance, intestinal permeability, intestinal tight junction (TJ) proteins expression, plasma bile acids concentration were evaluated. In addition, the effects of rat bile juice and dietary fat, possible mediators of the increase in the intestinal permeability in the obesity, on TJ permeability were explored in human intestinal Caco-2 cells.…”
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1218
Evaluation of clinical outcomes in children with intrahepatic cholestasis postpartial external biliary diversion: A single-center experience
Published 2023-01-01“…A significant improvement was detected in the 5-D itching score (p-value < 0.001), PedsQL (p-value < 0.001), and bile acids level (p-value 0.013). The preexisting growth failure was ameliorated. …”
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1219
Gut Microbiota Composition and Metabolites as the new Determinants of Cardiovascular Pathology Development
Published 2020-05-01“…In the majority of research SCFA and secondary bile acids have demonstrated protective role in CVD. …”
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1220
Supplementing a specific synbiotic suppressed the incidence of AOM/DSS-induced colorectal cancer in mice
Published 2023-06-01“…Moreover, the synbiotic significantly improved the disorder of the colonic microbiota of CAC mice, promoted the formation of SCFAs and the production of secondary bile acids, and alleviated the accumulation of primary bile acids in the CAC mice. …”
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Article