The Serum Profile of Transferrin Isoforms in Pancreatitis by Agnieszka Mucha, Malgorzata Zaczek, Michal Kralisz, Ewa Gruszewska, Bogdan Cylwik, Anatol Panasiuk, Lech Chrostek

“…Considering the etiology of acute pancreatitis, we noticed higher values of bile acids and γ-glutamyltransferase in acute pancreatitis of alcoholic etiology than that in pancreatitis of other etiologies. …”
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Cryo-EM Structures of AcrD Illuminate a Mechanism for Capturing Aminoglycosides from Its Central Cavity by Zhemin Zhang, Christopher E. Morgan, Meng Cui, Edward W. Yu

“…AcrD can also mediate resistance to a limited range of other amphiphilic agents, including bile acids, novobiocin, and fusidic acids. As there is no structural information available for any aminoglycoside-specific RND pump, here we describe cryo-electron microscopy (cryo-EM) structures of AcrD in the absence and presence of bound gentamicin. …”
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Severe intrahepatic cholestasis of pregnancy due to a Sertoli-Leydig cell tumour in a woman with polycystic ovary syndrome: a case report by Feng Yun, Leyi Fu, Dong Xu, Fan Qu, Fangfang Wang

“…Abstract Background Intrahepatic cholestasis of pregnancy (ICP) is a common gestational complication characterized by pruritus and elevated bile acids, usually occurring in the third trimester when the serum estrogen and progesterone levels are highest. …”
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Gebelik Kolestazlı Gebelerde Safra Asit Seviyeleri Perinatal Komplikasyonları Tahmin Etmede Yardımcı mıdır? by Kudret ERKENEKLİ, Cantekin ISKENDER, Hasan TOPÇU, Tugba ENSAR, Dilek UYGUR, Nuri DANİSMAN

“…Araştırma Makalesi / Research Article 212 Cilt/Volume 40 Yıl/Year 2015 Postprandial Bile Acids in ICP Bulgular: Gestasyonel diyabet ve preterm doğum intrahepatik kolestazlı gebelerde daha sıklıkla izlendi. …”
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Effects of Perfluorooctanoic Acid on Gut Microbiota and Microbial Metabolites in C57BL/6J Mice by Bei Gao, Lixia Chen, Weichen Xu, Jinjun Shan, Weishou Shen, Nan Gao

“…Significant alterations of gut-microbiota-related metabolites were induced by PFOA exposure, including bile acids and tryptophan metabolites such as 3-indoleacrylic acid and 3-indoleacetic acid. …”
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Seasonal dietary shifts alter the gut microbiota of a frugivorous lizard Teratoscincus roborowskii (Squamata, Sphaerodactylidae) by Wei‐Zhen Gao, Yi Yang, Lei Shi

“…Metabolomic profiling also revealed differences mainly related to the formation of secondary bile acids. The pantothenate and CoA biosynthesis, and lysine degradation pathways identified by KEGG enrichment symbolize the exuberant metabolic capacity of T. roborowskii. …”
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The Pathophysiological Role of CoA by Aleksandra Czumaj, Sylwia Szrok-Jurga, Areta Hebanowska, Jacek Turyn, Julian Swierczynski, Tomasz Sledzinski, Ewa Stelmanska

“…Coenzyme A participates in more than 100 different catabolic and anabolic reactions, including those involved in the metabolism of lipids, carbohydrates, proteins, ethanol, bile acids, and xenobiotics. However, much less is known about the importance of the concentration of this cofactor in various cell compartments and the role of altered CoA concentration in various pathologies. …”
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Biofilms and Benign Colonic Diseases by Busara Songtanin, Christopher J. Peterson, Adebayo J. Molehin, Kenneth Nugent

“…These methods that might include the measurement of quorum sensing molecules, measurement of bile acids, and identification of bacteria uniquely associated with biofilms in the colon.…”
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Pathogenesis and treatment of non-alcoholic steatohepatitis and its fibrosis by Kuei-Chuan Lee, Pei-Shan Wu, Han-Chieh Lin

“…Translocation of bacteria or its end-products entering the liver could activate hepatocytes, Kupffer cells, and hepatic stellate cells, exacerbating hepatic steatosis, inflammation, and fibrosis. Bile acids regulate glucose and lipid metabolism through Farnesoid X receptors in the liver and intestine. …”
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Screening for Preterm Birth: Potential for a Metabolomics Biomarker Panel by Elizabeth C. Considine, Ali S. Khashan, Louise C. Kenny

“…This biomarker panel contained mostly features from groups already associated in the literature with preterm birth and consisted of 4 features from the biological groups of “Bile Acids”, “Prostaglandins”, “Vitamin D and derivatives” and “Fatty Acids and Conjugates”.…”
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The Relationship between the Gut Microbiome and Metformin as a Key for Treating Type 2 Diabetes Mellitus by Chae Bin Lee, Soon Uk Chae, Seong Jun Jo, Ui Min Jerng, Soo Kyung Bae

“…Thus, several studies on rodents have suggested potential mechanisms interacting with the gut microbiome, including regulation of glucose metabolism, an increase in short-chain fatty acids, strengthening intestinal permeability against lipopolysaccharides, modulating the immune response, and interaction with bile acids. Furthermore, human studies have demonstrated evidence substantiating the hypotheses based on rodent studies. …”
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Investigating the Electro-Optic Response of Steroid Doped Liquid Crystal Devices by Steven M. Wolf, Zachary M. Marsh, Steven M. Quarin, Kyung Min Lee, Sushma Karra, Michael E. McConney, Tod A. Grusenmeyer, Nicholas P. Godman

“…Here, 10 naturally occurring biomolecules comprised of steroids and bile acids were tested as chiral dopants for CLCs. Progesterone was identified as having high miscibility with nematic liquid crystals and was used in responsive liquid crystal devices. …”
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Effect of selective plasmadsorption on systemic inflammatory response and cytokine levels in obstructed jaundice by А. M. Fomin

“…A signifcant decrease in the levels of total bilirubin by 39.8 ± 3.8%, conjugated bilirubin (by 38.2%), unconjugated bilirubin (by 32.5%), ALT (by 23.5%), AST (by 37%), and bile acids (by 31.4%) was revealed by the end of the procedure. …”
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Peroxisomal regulation of energy homeostasis: Effect on obesity and related metabolic disorders by Brian Kleiboeker, Irfan J. Lodhi

“…However, their cellular functions extend well beyond reactive oxygen species (ROS) metabolism and include fatty acid oxidation of unique substrates that cannot be catabolized in mitochondria, and synthesis of ether lipids and bile acids. Metabolic functions of peroxisomes involve crosstalk with other organelles, including mitochondria, endoplasmic reticulum, lipid droplets and lysosomes. …”
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Genetic alterations and molecular mechanisms underlying hereditary intrahepatic cholestasis by Shuying Xie, Shizhang Wei, Xiao Ma, Ruilin Wang, Tingting He, Zhao Zhang, Ju Yang, Jiawei Wang, Lei Chang, Manyi Jing, Haotian Li, Xuelin Zhou, Yanling Zhao, Yanling Zhao

“…Hereditary cholestatic liver disease caused by a class of autosomal gene mutations results in jaundice, which involves the abnormality of the synthesis, secretion, and other disorders of bile acids metabolism. Due to the existence of a variety of gene mutations, the clinical manifestations of children are also diverse. …”
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Gut-Microbial Metabolites, Probiotics and Their Roles in Type 2 Diabetes by Lixiang Zhai, Jiayan Wu, Yan Y. Lam, Hiu Yee Kwan, Zhao-Xiang Bian, Hoi Leong Xavier Wong

“…In the present article, we reviewed the pathological role of gut microbial metabolites including gaseous products, branched-chain amino acids (BCAAs) products, aromatic amino acids (AAAs) products, bile acids (BA) products, choline products and bacterial toxins in regulating insulin sensitivity in T2D. …”
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STUDY OF PHYSICO-CHEMICAL PROPERTIES OF BILE AFTER CHOLECYSTECTOMY ON CHOLELITHIASI S by Ya. M. Vakhrushev, N. A. Khokhlacheva, T. Yu. Maksimova

“…The study of the chemical composition of the hepatic bile of patients of both groups revealed an increase in cholesterol, total sialic acids and total protein, a decrease in bile acids, phospholipids, cholate-cholesterol and phospholipid-cholesterol coefficients. …”
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Regulation of Cholesterol Metabolism by Bioactive Components of Soy Proteins: Novel Translational Evidence by Giusy Rita Caponio, David Q.-H. Wang, Agostino Di Ciaula, Maria De Angelis, Piero Portincasa

“…An important amount of cholesterol originates from hepatic synthesis, and is secreted by the liver into bile together with bile acids (BA) and phospholipids, with all forming micelles and vesicles. …”
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Tea polyphenol – gut microbiota interactions: hints on improving the metabolic syndrome in a multi-element and multi-target manner by Hui Ma, Yaozhong Hu, Bowei Zhang, Zeping Shao, Eugeni Roura, Shuo Wang

“…The interactions between TPs and gut microbiota will lead to the alterations of gut microbiota composition and the production of metabolites including short chain fatty acids, bile acids, amino acids and TPs derived metabolites, accordingly exerting their biological effects both locally and systemically. …”
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Cholecystocardial syndrome in real clinical practice by D. I. Trukhan, E. N. Degovtsov, E. L. Davydov

“…The analysis of domestic data on the problem of cholecystocardial syndrome in real clinical practice, combined with data obtained as a result of a search of foreign literature on electronic biomedical databases (PubMed, MEDLINE, Scopus, Google Scholar) suggests the allocation of another mechanism of its development, associated with cholestasis, high levels of circulating bile acids and activation of bile acid receptors, and allows us to consider its cholecystocardial syndrome not only as a diagnostic syndrome during differential diagnosis, but also as a syndrome reflecting the comorbidity of the pathology of CVS and the biliary tract.…”
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