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1481
The Serum Profile of Transferrin Isoforms in Pancreatitis
Published 2022-03-01“…Considering the etiology of acute pancreatitis, we noticed higher values of bile acids and γ-glutamyltransferase in acute pancreatitis of alcoholic etiology than that in pancreatitis of other etiologies. …”
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1482
Cryo-EM Structures of AcrD Illuminate a Mechanism for Capturing Aminoglycosides from Its Central Cavity
Published 2023-02-01“…AcrD can also mediate resistance to a limited range of other amphiphilic agents, including bile acids, novobiocin, and fusidic acids. As there is no structural information available for any aminoglycoside-specific RND pump, here we describe cryo-electron microscopy (cryo-EM) structures of AcrD in the absence and presence of bound gentamicin. …”
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1483
Severe intrahepatic cholestasis of pregnancy due to a Sertoli-Leydig cell tumour in a woman with polycystic ovary syndrome: a case report
Published 2022-11-01“…Abstract Background Intrahepatic cholestasis of pregnancy (ICP) is a common gestational complication characterized by pruritus and elevated bile acids, usually occurring in the third trimester when the serum estrogen and progesterone levels are highest. …”
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1484
Gebelik Kolestazlı Gebelerde Safra Asit Seviyeleri Perinatal Komplikasyonları Tahmin Etmede Yardımcı mıdır?
Published 2015-09-01“…Araştırma Makalesi / Research Article 212 Cilt/Volume 40 Yıl/Year 2015 Postprandial Bile Acids in ICP Bulgular: Gestasyonel diyabet ve preterm doğum intrahepatik kolestazlı gebelerde daha sıklıkla izlendi. …”
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1485
Effects of Perfluorooctanoic Acid on Gut Microbiota and Microbial Metabolites in C57BL/6J Mice
Published 2023-05-01“…Significant alterations of gut-microbiota-related metabolites were induced by PFOA exposure, including bile acids and tryptophan metabolites such as 3-indoleacrylic acid and 3-indoleacetic acid. …”
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1486
Seasonal dietary shifts alter the gut microbiota of a frugivorous lizard Teratoscincus roborowskii (Squamata, Sphaerodactylidae)
Published 2023-08-01“…Metabolomic profiling also revealed differences mainly related to the formation of secondary bile acids. The pantothenate and CoA biosynthesis, and lysine degradation pathways identified by KEGG enrichment symbolize the exuberant metabolic capacity of T. roborowskii. …”
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1487
The Pathophysiological Role of CoA
Published 2020-11-01“…Coenzyme A participates in more than 100 different catabolic and anabolic reactions, including those involved in the metabolism of lipids, carbohydrates, proteins, ethanol, bile acids, and xenobiotics. However, much less is known about the importance of the concentration of this cofactor in various cell compartments and the role of altered CoA concentration in various pathologies. …”
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1488
Biofilms and Benign Colonic Diseases
Published 2022-11-01“…These methods that might include the measurement of quorum sensing molecules, measurement of bile acids, and identification of bacteria uniquely associated with biofilms in the colon.…”
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1489
Pathogenesis and treatment of non-alcoholic steatohepatitis and its fibrosis
Published 2023-01-01“…Translocation of bacteria or its end-products entering the liver could activate hepatocytes, Kupffer cells, and hepatic stellate cells, exacerbating hepatic steatosis, inflammation, and fibrosis. Bile acids regulate glucose and lipid metabolism through Farnesoid X receptors in the liver and intestine. …”
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1490
Screening for Preterm Birth: Potential for a Metabolomics Biomarker Panel
Published 2019-05-01“…This biomarker panel contained mostly features from groups already associated in the literature with preterm birth and consisted of 4 features from the biological groups of “Bile Acids”, “Prostaglandins”, “Vitamin D and derivatives” and “Fatty Acids and Conjugates”.…”
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1491
The Relationship between the Gut Microbiome and Metformin as a Key for Treating Type 2 Diabetes Mellitus
Published 2021-03-01“…Thus, several studies on rodents have suggested potential mechanisms interacting with the gut microbiome, including regulation of glucose metabolism, an increase in short-chain fatty acids, strengthening intestinal permeability against lipopolysaccharides, modulating the immune response, and interaction with bile acids. Furthermore, human studies have demonstrated evidence substantiating the hypotheses based on rodent studies. …”
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1492
Investigating the Electro-Optic Response of Steroid Doped Liquid Crystal Devices
Published 2023-04-01“…Here, 10 naturally occurring biomolecules comprised of steroids and bile acids were tested as chiral dopants for CLCs. Progesterone was identified as having high miscibility with nematic liquid crystals and was used in responsive liquid crystal devices. …”
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1493
Effect of selective plasmadsorption on systemic inflammatory response and cytokine levels in obstructed jaundice
Published 2021-11-01“…A signifcant decrease in the levels of total bilirubin by 39.8 ± 3.8%, conjugated bilirubin (by 38.2%), unconjugated bilirubin (by 32.5%), ALT (by 23.5%), AST (by 37%), and bile acids (by 31.4%) was revealed by the end of the procedure. …”
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1494
Peroxisomal regulation of energy homeostasis: Effect on obesity and related metabolic disorders
Published 2022-11-01“…However, their cellular functions extend well beyond reactive oxygen species (ROS) metabolism and include fatty acid oxidation of unique substrates that cannot be catabolized in mitochondria, and synthesis of ether lipids and bile acids. Metabolic functions of peroxisomes involve crosstalk with other organelles, including mitochondria, endoplasmic reticulum, lipid droplets and lysosomes. …”
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1495
Genetic alterations and molecular mechanisms underlying hereditary intrahepatic cholestasis
Published 2023-05-01“…Hereditary cholestatic liver disease caused by a class of autosomal gene mutations results in jaundice, which involves the abnormality of the synthesis, secretion, and other disorders of bile acids metabolism. Due to the existence of a variety of gene mutations, the clinical manifestations of children are also diverse. …”
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1496
Gut-Microbial Metabolites, Probiotics and Their Roles in Type 2 Diabetes
Published 2021-11-01“…In the present article, we reviewed the pathological role of gut microbial metabolites including gaseous products, branched-chain amino acids (BCAAs) products, aromatic amino acids (AAAs) products, bile acids (BA) products, choline products and bacterial toxins in regulating insulin sensitivity in T2D. …”
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1497
STUDY OF PHYSICO-CHEMICAL PROPERTIES OF BILE AFTER CHOLECYSTECTOMY ON CHOLELITHIASI S
Published 2018-08-01“…The study of the chemical composition of the hepatic bile of patients of both groups revealed an increase in cholesterol, total sialic acids and total protein, a decrease in bile acids, phospholipids, cholate-cholesterol and phospholipid-cholesterol coefficients. …”
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1498
Regulation of Cholesterol Metabolism by Bioactive Components of Soy Proteins: Novel Translational Evidence
Published 2020-12-01“…An important amount of cholesterol originates from hepatic synthesis, and is secreted by the liver into bile together with bile acids (BA) and phospholipids, with all forming micelles and vesicles. …”
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1499
Tea polyphenol – gut microbiota interactions: hints on improving the metabolic syndrome in a multi-element and multi-target manner
Published 2022-01-01“…The interactions between TPs and gut microbiota will lead to the alterations of gut microbiota composition and the production of metabolites including short chain fatty acids, bile acids, amino acids and TPs derived metabolites, accordingly exerting their biological effects both locally and systemically. …”
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1500
Cholecystocardial syndrome in real clinical practice
Published 2021-04-01“…The analysis of domestic data on the problem of cholecystocardial syndrome in real clinical practice, combined with data obtained as a result of a search of foreign literature on electronic biomedical databases (PubMed, MEDLINE, Scopus, Google Scholar) suggests the allocation of another mechanism of its development, associated with cholestasis, high levels of circulating bile acids and activation of bile acid receptors, and allows us to consider its cholecystocardial syndrome not only as a diagnostic syndrome during differential diagnosis, but also as a syndrome reflecting the comorbidity of the pathology of CVS and the biliary tract.…”
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