BIOSKIN: A Protocol for the Copenhagen Translational Skin Immunology Biobank and Research Programme ανά Lone Skov, Jeanne Duus Johansen, Marianne Bengtson Løvendorf

“…Introduction Psoriasis, atopic dermatitis and contact dermatitis are common chronic inflammatory skin diseases that have a significant impact on individuals and society.Methods and analysis The Copenhagen Translational Skin Immunology Biobank and Research Programme (BIOSKIN) is a translational biobank and research study that aims to prospectively collect high-quality biological samples and clinical data from 3000 patients with psoriasis, atopic dermatitis and contact dermatitis over a minimum period of 5 years. …”
Λήψη πλήρους κειμένου

Asthma exacerbations and eosinophilia in the UK Biobank: a genome-wide association study ανά Ahmed Edris, Kirsten Voorhies, Sharon M. Lutz, Carlos Iribarren, Ian Hall, Ann Chen Wu, Martin Tobin, Katherine Fawcett, Lies Lahousse

“…We sought replication for suggestive associations (p<5×10−6) in the GERA cohort. Results In the UK Biobank, we identified 11 604 cases and 37 890 controls. …”
Λήψη πλήρους κειμένου

Establishing a cryopreserved biobank of living tumor tissues for drug sensitivity testing ανά Ping Chen, Jing-Bo Zhou, Xiang-Peng Chu, Yang-Yang Feng, Qi-Bing Zeng, Josh-Haipeng Lei, Ka-Pou Wong, Tai-Ip Chan, Chon-Wa Lam, Wen-Li Zhu, Wai-Kuok Chu, Feng Hu, Guang-Hui Luo, Kin-Iong Chan, Chu-Xia Deng

Θέματα: “…Biobank…”
Λήψη πλήρους κειμένου

Biobank data for studying the genetic architecture of osteoporosis and developing genetic risk scores ανά E. A. Sotnikova, A. V. Kiseleva, A. N. Meshkov, A. I. Ershova, A. A. Ivanova, M. A. Kolchina, V. A. Kutsenko, I. A. Skripnikova, O. M. Drapkina

Θέματα: Λήψη πλήρους κειμένου

Biobank-scale methods and projections for sparse polygenic prediction from machine learning ανά Timothy G. Raben, Louis Lello, Erik Widen, Stephen D. H. Hsu

“…Using LASSO, we develop a novel method for projecting AUC and correlation as a function of data size (i.e., for new biobanks) and characterize the asymptotic limit of performance. …”
Λήψη πλήρους κειμένου

Standardizing digital biobanks: integrating imaging, genomic, and clinical data for precision medicine ανά Valentina Brancato, Giuseppina Esposito, Luigi Coppola, Carlo Cavaliere, Peppino Mirabelli, Camilla Scapicchio, Rita Borgheresi, Emanuele Neri, Marco Salvatore, Marco Aiello

Θέματα: Λήψη πλήρους κειμένου

Poland - National regulation on processing data for scientific research purposes and biobanking activities ανά Joanna Osiejewicz, Olha V. Shapovalova, Olena М. Ivanii, Oleksandr V. Kolyshkin, Svitlana V. Gvozdetska

“…Biobanks raise great hopes for future research that can help understand many diseases and find ways to treat them. …”
Λήψη πλήρους κειμένου

Pinning beetles, biobanking futures: practices of archiving life in a time of extinction ανά Adrian Van Allen

Θέματα: Λήψη πλήρους κειμένου

Detecting Parkinson’s Disease from Wrist-Worn Accelerometry in the U.K. Biobank ανά Williamson, James R., Telfer, Brian, Mullany, Riley, Friedl, Karl E.

“…As an initial proof of concept for this technological approach, we analyzed the U.K. Biobank data set, consisting of one week of wrist-worn accelerometry from a population with a PD primary diagnosis and an age-matched healthy control population. …”
Λήψη πλήρους κειμένου

Significant Sparse Polygenic Risk Scores across 813 traits in UK Biobank ανά Tanigawa, Yosuke, Qian, Junyang, Venkataraman, Guhan, Justesen, Johanne Marie, Li, Ruilin, Tibshirani, Robert, Hastie, Trevor, Rivas, Manuel A.

“…The sparse PRS model trained on European individuals showed limited transferability when evaluated on non-European individuals in the UK Biobank. We provide the PRS model weights on the Global Biobank Engine (https://biobankengine.stanford.edu/prs).…”
Λήψη πλήρους κειμένου

Comparison of sociodemographic and health-related characteristics of UK Biobank participants with the general population ανά Fry, A, Littlejohns, T, Sudlow, C, Doherty, N, Adamska, L, Sprosen, T, Collins, R, Allen, N

“…UK Biobank is a population-based cohort of 500,000 participants recruited between 2006 and 2010. …”

Body fat distribution, fat-free mass and cardiovascular function in the UK Biobank ανά Oguntade, AS, Lacey, B, Taylor, H, Lewington, S

“…<p><strong>Methods</strong></p> The present analysis included 23,258 individuals (mean age 63 years, 53% women) who participated in the whole body imaging sub-study of the UK Biobank. Associations of body composition measures with each of LVEF and PWASI, after mutual adjustment for one another and potential confounders, were determined using multivariable linear regression. …”

Risk prediction for cardiovascular disease using ECG data in the China Kadoorie Biobank ανά Shen, Y, Yang, Y, Parish, S, Chen, Z, Clarke, R, Clifton, D

BMI and cause‐specific hospital admissions and costs: The UK Biobank cohort study ανά O’Halloran, R, Mihaylova, B, Cairns, BJ, Kent, S

“…</p> <p><strong>Methods</strong> For 451,320 men and women aged 40 years or older recruited into the UK Biobank, followed up for 6 years on average, this study estimated annual rates and costs (at 2016 UK prices) of hospital admissions, overall and by diagnostic category (using International Classification of Diseases, Tenth Revision chapters), in relation to BMI.…”

SAIL--a software system for sample and phenotype availability across biobanks and cohorts. ανά Gostev, M, Fernandez-Banet, J, Rung, J, Dietrich, J, Prokopenko, I, Ripatti, S, McCarthy, M, Brazma, A, Krestyaninova, M

“…SUMMARY: The Sample avAILability system-SAIL-is a web based application for searching, browsing and annotating biological sample collections or biobank entries. By providing individual-level information on the availability of specific data types (phenotypes, genetic or genomic data) and samples within a collection, rather than the actual measurement data, resource integration can be facilitated. …”

Biomarker concentrations in white and British Indian vegetarians and non-vegetarians in the UK Biobank ανά Perez-Cornago, A, Bradbury, K, Key, T

“…</p> <p><strong>Methods:</strong> The UK Biobank recruited 500,000 participants aged 40-69 years (54.4% women) throughout the United Kingdom in 2006-2010. …”

The relative validity and reproducibility of food frequency questionnaires in the China Kadoorie Biobank Study ανά Qin, C, Guo, Y, Pei, P, Du, H, Yang, L, Chen, Y, Shen, X, Shi, Z, Qi, L, Chen, J, Chen, Z, Yu, C, Lv, J, Li, L

“…<br> <strong>Methods:</strong> This study compared 12-day 24-h dietary recalls with qualitative and quantitative FFQs designed by the China Kadoorie Biobank (CKB) study to assess the relative validity. …”

Consent for biobanking: The legal frameworks of countries in the BioSHaRE-EU project. ανά Kaye, J, Briceño Moraia, L, Curren, L, Bell, J, Mitchell, C, Soini, S, Hoppe, N, Øien, M, Rial-Sebbag, E

“…This article analyzes the legislative frameworks that apply to biobanking activities to identify differences in legal requirements between the BioSHaRE-EU project countries: Finland, France, Germany, the Netherlands, Norway, and the United Kingdom. …”

Cohort Profile: The Korean Cancer Prevention Study-II (KCPS-II) Biobank ανά Jee, Y, Emberson, J, Jung, K, Lee, S, Lee, S, Back, J, Hong, S, Kimm, H, Sherliker, P, Jee, S, Lewington, S

UK Biobank imaging adapted for a real‐world memory clinic sample ανά Griffanti, L, Gillis, G, O'Donoghue, MC, Blane, J, Pretorius, PM, Mitchell, R, Aikin, N, Lindsay, K, Campbell, J, Semple, J, Martos, L, Raymont, V, MacKay, C