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7301
Genetic alterations of CDX1, CYLD and CDKN2B genes in CRC
Published 2021-09-01“…Materials and Methods: Specimens of CRC from 72 individuals with confirmation of pathology report, were provided and bought from the Biobanks. Real-time PCR was used to examine the expression of CDX1, CYLD, and CDKN2B genes in tumoral and non-tumoral tissues. …”
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7302
Big data in corneal diseases and cataract: Current applications and future directions
Published 2023-02-01“…Within the field of ophthalmology, there is a rapidly expanding pool of large clinical registries, epidemiological studies, omics studies, and biobanks through which big data can be accessed. National corneal transplant registries, genome-wide association studies, national cataract databases, and large ophthalmology-related EHR-based registries (e.g., AAO IRIS Registry) are some of the key resources. …”
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7303
Detection of Biomarkers with Solid-Phase Proximity Ligation Assay in Patients with Colorectal Cancer
Published 2016-06-01“…BACKGROUND: In the search for prognostic biomarkers, a significant amount of precious biobanked blood samples is needed for conventional analyses. …”
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7304
Practical tips to using formalin-fixed paraffin-embedded tissue archives for molecular diagnostics in a South African setting
Published 2022-06-01“…Background: Formalin-fixed paraffin-embedded (FFPE) tissue archives in hospitals, biobanks, and others offer a vast collection of extensive, readily available specimens for molecular testing. …”
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7305
<i>All of Us</i> and the Promise of Precision Medicine: Achieving Equitable Access for Federally Qualified Health Center Patients
Published 2023-03-01“…The United States National Institutes of Health’s (NIH) <i>All of Us</i> (AoU) initiative recruits participants from diverse backgrounds to improve the makeup of biobanks, considering nearly all biospecimens used in research come from people of European ancestry. …”
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7306
The Prognostic and Predictive Value of Melanoma-related MicroRNAs Using Tissue and Serum: A MicroRNA Expression Analysis
Published 2015-07-01“…We measured the expression of a panel of 17 microRNAs (miRNAs) (MELmiR-17) in melanoma tissues (stage III; n = 76 and IV; n = 10) and serum samples (collected from controls with no melanoma, n = 130; and patients with melanoma (stages I/II, n = 86; III, n = 50; and IV, n = 119)) obtained from biobanks in Australia and Germany. In melanoma tissues, members of the ‘MELmiR-17’ panel were found to be predictors of stage, recurrence, and survival. …”
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7307
OCMA: Fast, Memory-Efficient Factorization of Prohibitively Large Relationship Matrices
Published 2019-01-01“…However, the GRMs and genotype matrices provided by modern biobanks are too large to be stored in active memory. …”
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7308
The relationship between adipokine levels and bone mass—A systematic review
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7309
Pre-analytical sample quality: metabolite ratios as an intrinsic marker for prolonged room temperature exposure of serum samples.
Published 2015-01-01“…Many omics studies take advantage of biobanked samples to meet this need. Most of the laboratory errors occur in the pre-analytical phase. …”
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7310
The concept of General Consent in Switzerland and the implementation at the University Hospital Zurich, a cross-sectional study
Published 2022-04-01“… BACKGROUND: General Consent (GC) allows the further use of health-related data/samples for multiple, unspecified research projects and/or for the collection in databases and biobanks in Switzerland. The application of General Consent in the context of human research is regulated within the scope of the Human Research Act. …”
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7311
Integrating questionnaire measures for transdiagnostic psychiatric phenotyping using word2vec.
Published 2020-01-01“…We utilized nine self-report symptom measures drawn from a large cellular biobanking study that enrolled individuals with mood and psychotic disorders, as well as healthy controls. …”
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7312
High reproducibility of histological characterization by whole virtual slide quantification; an example using carotid plaque specimens.
Published 2014-01-01“…OBJECTIVE:Tissue biobanks are an important source for discovery and validation studies aiming for new proteins that are causally related with disease development. …”
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7313
Personalization: the future of medical cannabis?
Published 2020-03-01“…Especially since in Poland there is no proper law regarding genetic testing and biobanking... The other thing is that Cannabis flos, like other herbal medicinal products, can cause drug-drug interactions. …”
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7314
Impact of storage conditions on the quality of nucleic acids in paraffin embedded tissues.
Published 2018-01-01“…Furthermore, biomedical research and biomarker development critically relies on using long-term stored PET from medical archives or biobanks to correlate molecular features with long-term disease outcomes. …”
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7315
Quality of DNA extracted from saliva samples collected with the Oragene™ DNA self-collection kit
Published 2012-05-01“…<p>Abstract</p> <p>Background</p> <p>Large epidemiological studies in DNA biobanks have increasingly used less invasive methods for obtaining DNA samples, such as saliva collection. …”
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7316
Effect of storage and temperature on two biochemical analytes (creatinine and urea) in pooled serum samples stored at -20°C
Published 2017-01-01“…Optimal storage of serum specimens in biobanks for long time for multicenter reference interval studies remains to be determined. …”
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7317
Reduced leukocyte mitochondrial copy number in metabolic syndrome and metabolically healthy obesity
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7318
Cardiogenic shock and tumor resection due to cardiac synovial sarcoma: a case report
Published 2022-07-01“…Systematic inclusion of patients in multicenter initiatives, including biobanking, is necessary. Better knowledge of genetic defects relevant to these cardiac tumors will promote accurate diagnoses and suggest novel and personalized gene-based therapies.…”
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7319
Personalized Critical Care Medicine (Review)
Published 2022-08-01“…The analysis of literature has demonstrated positive results of implementing PM principles in prevention, diagnosis and treatment of critically ill patients. Creation of Biobanks, development of training programs and regulatory documentation, advancing the scientific research, introduction of new methods of diagnosis and treatment will contribute to the implementation of PM principles in practical healthcare.…”
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7320
Study design of DIACORE (DIAbetes COhoRtE) – a cohort study of patients with diabetes mellitus type 2
Published 2013-02-01“…Blood samples are obtained for a centrally analyzed standard laboratory panel and for biobanking of aliquots of serum, plasma, urine, mRNA and DNA for future scientific use. …”
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