Virtual Cocrystal Screening of Adefovir Dipivoxyl: Identification of New Solid Forms with Improved Dissolution and Permeation Profiles by Rafael Barbas, Hanan Fael, Samuel Lee, Rebeca Ruiz, Christopher A. Hunter, Elisabet Fuguet, Clara Ràfols, Rafel Prohens

“…Moreover, dynamic dissolution experiments that simultaneously mimic both the pH variation along the gastrointestinal tract and the partition into biological membranes show that, in addition to the faster initial dissolution, Adefovir Dipivoxyl also penetrates faster into the organic membranes in the form of resorcinol and orcinol cocrystals.…”
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Interference of electron transfer chain inhibitors in bioelectrochemical systems by Hans Schneider, Bin Lai, Jens O. Krömer

“…This also provides an in vivo approach to investigating the extracellular electron transfer (EET) mechanisms within and across biological membranes in bioelectrochemical research. However, the applicability of these specific inhibitors in electrochemical systems remains to be validated, particularly when aiming for (semi-)quantitative evaluation of the contribution of specific redox proteins to the EET. …”
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Potential biocide roles of violacein by Ignacio Rivero Berti, Melisa E. Gantner, Santiago Rodriguez, German A. Islan, Wagner J. Fávaro, Alan Talevi, Guillermo R. Castro, Nelson Durán, Nelson Durán

“…The most relevant activities of violacein include the interference in the physiological activities of biological membranes, inhibition of cell proliferation, antioxidant, and anti-inflammatory activities. …”
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Nonlinear Cell Deformation Model by Mendová Katarína, Otáhal Martin, Daniel Matej

“…In this paper, we present a novel mathematical model designed specifically for analysing the mechanical properties of liposomes, which serve as model systems for studying biological membranes. Our model takes into account various factors such as stretching, bending, and contact adhesion during atomic force microscopy (AFM) indentation using a spherical tip. …”
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Beta-Caryophyllene Induces Significant Changes in the Lipid Bilayer at Room and Physiological Temperatures: ATR-FTIR Spectroscopy Studies by Ivan D. Yakimov, Ilya M. Kolmogorov, Irina M. Le-Deygen

“…However, to date, there are practically no data on the interaction of BCP with biological membranes. In the present work, we studied for the first time the interaction of BCP with model membranes—liposomes based on egg yolk phosphatidylcholine (Egg PC) with a variable cholesterol content (from 0 to 25 w.%). …”
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Membrane Association and Topology of Citrus Leprosis Virus C2 Movement and Capsid Proteins by Mikhail Oliveira Leastro, Juliana Freitas-Astúa, Elliot Watanabe Kitajima, Vicente Pallás, Jesús Á. Sánchez-Navarro

“…This study described the association of CiLV-C2 movement protein (MP) and capsid protein (p29) with biological membranes. Our findings obtained by computer predictions, chemical treatments after membrane fractionation, and biomolecular fluorescence complementation assays revealed that p29 is peripherally associated, while the MP is integrally bound to the cell membranes. …”
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Nonuniversal impact of cholesterol on membranes mobility, curvature sensing and elasticity by Matthias Pöhnl, Marius F. W. Trollmann, Rainer A. Böckmann

“…Abstract Biological membranes, composed mainly of phospholipids and cholesterol, play a vital role as cellular barriers. …”
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A Strategic Approach for Fluorescence Imaging of Membrane Proteins in a Native-like Environment by Swiecicki, Jean-Marie, Santana, Jordan Tyler, Imperiali, Barbara

“…© 2019 Elsevier Ltd Biological membranes are complex barriers in which membrane proteins and thousands of lipidic species participate in structural and functional interactions. …”
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Imaging lipid phase separation in droplet interface bilayers by Danial, J

“…It was proposed that biological membranes partition into lipid rafts that can promote and control the organization of membrane proteins to localize the mentioned processes. …”

Elastic modulus of suspended purple membrane measured by atomic force microscopy by Siitonen, A, Sumitomo, K, Ramanujan, C, Shinozaki, Y, Kasai, N, Furukawa, K, Ryan, J, Torimitsu, K

“…In this paper we demonstrate that the AFM allows us to evaluate the mechanics of biological membranes in their native conditions. © 2008 Elsevier B.V. …”

Peptide-based matrices as drug delivery vehicles. by Ezzat, K, Andaloussi, S, Abdo, R, Langel, U

“…However, breakthrough discoveries in the last decades identified some peptide-based matrices that posses the ability to traverse biological membranes, and many peptides, polypeptides and even complete proteins have been shown to have such properties. …”

Pore-forming toxins. by Gilbert, R

“…Pore-forming toxins are widely distributed proteins which form lesions in biological membranes. In this review, bacterial pore-forming toxins are treated as a paradigm and discussed in terms of the structural principles on which they work. …”

Photogenerated reagents for membranes: selective labeling of intrinsic membrane proteins in the human erythrocyte membrane. by Bayley, H, Knowles, JR

“…1-[3H]Spiro[adamantane-4,4'-diazirine], a lipophilic, photoactivatable reagent designed to label those segments of intrinsic proteins that lie within the lipid bilayer of biological membranes, has been evaluated. The reagent labels the intrinsic proteins of human erythrocyte membranes far more heavily than it labels the extrinsic proteins. …”

Pediatric Biopharmaceutical Classification Systems (pBCS) by Justyna Srebro, Witold Brniak, Renata Jachowicz, Klaudia Syty, Katarzyna Tomaś

“…The system includes classifying medicinal substances into 4 classes with different solubility and permeability through biological membranes, which directly impacts the drug's disposition after oral administration. …”
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Biotechnological Evolution of siRNA Molecules: From Bench Tool to the Refined Drug by Danielle de Brito e Cunha, Ana Beatriz Teixeira Frederico, Tamiris Azamor, Juliana Gil Melgaço, Patricia Cristina da Costa Neves, Ana Paula Dinis Ano Bom, Tatiana Martins Tilli, Sotiris Missailidis

“…Major extracellular barriers are enzymatic degradation of siRNAs by serum endonucleases and RNAases, renal clearance of the siRNA delivery system, the impermeability of biological membranes for siRNA, activation of the immune system, plasma protein sequestration, and capillary endothelium crossing. …”
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Research progress on the role of transmembrane proteins in malignant tumors by WANG Zihao, XIA Xiaochao, LI Shun

“…Transmembrane proteins (TMEMs) are a class of family proteins that span lipid bilayers, serving as crucial channel proteins on biological membranes, playing essential physiological roles. …”
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Adhesions in the setting of hip arthroscopy by Joseph J Ruzbarsky, Rui W Soares, Spencer M Comfort, Justin W Arner, Marc J Philippon

“…Treatment options for adhesion formation includes surgical lysis of adhesions with or without placement of biologic membranes aimed at inhibiting adhesion reformation as well as systemic medications to further reduce the risk. …”
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Chirality-Dependent Interaction of d- and l-Menthol with Biomembrane Models by Pooja Gusain, Shinya Ohki, Kunihide Hoshino, Yoshio Tsujino, Naofumi Shimokawa, Masahiro Takagi

“…Chirality plays a vital role in biological membranes and has a significant effect depending on the type and arrangement of the isomer. …”
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Status of surfactants as penetration enhancers in transdermal drug delivery by Iti Som, Kashish Bhatia, Mohd. Yasir

“…Surfactants have effects on the permeability characteristics of several biological membranes including skin. They have the potential to solubilize lipids within the stratum corneum. …”
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Experimental and Theoretical Analysis of Metal Complex Diffusion through Cell Monolayer by Katarzyna Gałczyńska, Jarosław Rachuna, Karol Ciepluch, Magdalena Kowalska, Sławomir Wąsik, Tadeusz Kosztołowicz, Katarzyna D. Lewandowska, Jacek Semaniak, Krystyna Kurdziel, Michał Arabski

“…The study of drugs diffusion through different biological membranes constitutes an essential step in the development of new pharmaceuticals. …”
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