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301
The Fabrication of Polymer-Based Curcumin-Loaded Formulation as a Drug Delivery System: An Updated Review from 2017 to the Present
Published 2024-01-01“…It is commonly administered through oral and transdermal routes in different forms, where the particle size is one of the most common barriers that decreases its absorption through biological membranes on the targeted sites and limits its clinical effectiveness. …”
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302
Partitioning of fluoxetine into mixed lipid bilayer containing 1,2-dipalmitoyl-sn-glycero-3-phosphoglycerol (DPPG) and 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC)
Published 2022-03-01“…This study adds a deeper understanding of how antidepressant fluoxetine exerts its effect on anioniccontaining biological membranes, shedding light onto drug delivery systems in the pharmaceutical field. …”
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303
Nucleic acid amphiphiles: Synthesis, properties, and applications
Published 2023-09-01“…Since nucleic acids are intrinsically hydrophilic, the hydrophobic groups endow nucleic acid amphiphiles with unique properties, such as self-assembling, interactions with artificial or biological membranes, and transmembrane transport. Importantly, the hybridization or target binding capability of oligonucleotide itself supplies nucleic acid amphiphiles with excellent programmability. …”
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304
Mutational scanning reveals the determinants of protein insertion and association energetics in the plasma membrane
Published 2016-01-01“…The assay quantifies insertion energetics for all natural amino acids at 27 positions across the membrane, revealing that the hydrophobicity of biological membranes is significantly higher than appreciated. …”
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305
Hidden linear defects in surfactant onions revealed by coalescence into lamellar layers
Published 2021-11-01“…The onion-like multilamellar structure is ubiquitous in various soft materials, such as surfactant solutions, biological membranes, and block copolymers, as well as hard materials such as carbon. …”
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306
Entropy Contribution to the Line Tension: Insights from Polymer Physics, Water String Theory, and the Three-Phase Tension
Published 2018-09-01“…The estimated value of the entropic input into the line tension is close to experimental findings, reported by various groups, and seems to be relevant for the understanding of elastic properties of biological membranes.…”
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307
Cold and freezing injury in insects: An overview of molecular mechanisms
Published 2022-01-01“…The review shows that injury primarily occurs at the molecular level in terms of damage to proteins, nucleic acids and biological membranes. The damage to macromolecular structures occurs as a result of the interaction between the effects of temperature, ice formation and resulting secondary effects such as osmotic stress, increased concentration of solutes, cellular freeze dehydration, disruption of ionic balance and oxidative stress. …”
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308
Small-Angle Neutron Scattering for Studying Lipid Bilayer Membranes
Published 2022-10-01“…Small-angle neutron scattering (SANS) is a powerful tool for studying biological membranes and model lipid bilayer membranes. The length scales probed by SANS, being from 1 nm to over 100 nm, are well-matched to the relevant length scales of the bilayer, particularly when it is in the form of a vesicle. …”
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309
The Advanced Lipoxidation End-Product Malondialdehyde-Lysine in Aging and Longevity
Published 2020-11-01“…The degree of unsaturation of biological membranes and the intracellular oxidative conditions are the main factors that modulate MDALys formation. …”
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310
Investigating lipid bilayer self-assembly and formation of ripple phase: Insights from a coarse-grained implicit solvent model
Published 2024-01-01“…By shedding light on the ripple phase, a phase previously difficult to simulate convincingly, the insights gained from this study have the potential to guide future investigations into the behavior of biological membranes and their role in cellular processes.…”
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311
Deciphering lipid dysregulation in ALS: from mechanisms to translational medicine
Published 2022-11-01“…Lipids not only regulate integrity and fluidity of biological membranes, but also serve as energy storage and bioactive molecules for signaling. …”
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312
Dynamic Nuclear Polarization of Biomembrane Assemblies
Published 2020-08-01“…Fully exploiting NMR capabilities to study membrane proteins is further hampered by their dilution within biological membranes. Recent developments in dynamic nuclear polarization (DNP), which can transfer the relatively high polarization of unpaired electrons to nuclear spins, show promise for overcoming the sensitivity bottleneck and enabling NMR characterization of membrane proteins under native-like conditions. …”
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313
Hydrophobic matching dictates over the linear rule of mixtures in binary lipid membranes
Published 2024“…Biological membranes feature heterogeneous mixtures of lipids with different head and tail characteristics. …”
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Journal Article -
314
Aquaporin engineering, a computational approach
Published 2013“…Aquaporin is a family of membrane proteins devoted to transporting water molecules across biological membranes. This protein family is ubiquitously present in all three kingdoms of life, the Archea, Eubacteria and Eukaryotes. …”
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Student Research Poster -
315
The PM2 virion has a novel organization with an internal membrane and pentameric receptor binding spikes.
Published 2004“…Biological membranes are notoriously resistant to structural analysis. …”
Journal article -
316
A review on fatty acid desaturases of psycrophilic bacteria and unsaturated fatty acids
Published 2014“…Unsaturated fatty acids play significant role in maintaining the right structure and functioning of biological membranes of all organisms. Psychrophilic bacteria survive low temperatures with 15 °C and 20 °C as the optima and maxima respectively. …”
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Conference or Workshop Item -
317
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318
Cellular Compartmentalization, Glutathione Transport and Its Relevance in Some Pathologies
Published 2023-03-01“…GSH is involved in the detoxification of free radicals, peroxides and xenobiotics (drugs, pollutants, carcinogens, etc.), protects biological membranes from lipid peroxidation, and is an important regulator of cell homeostasis, since it participates in signaling redox, regulation of the synthesis and degradation of proteins (S-glutathionylation), signal transduction, various apoptotic processes, gene expression, cell proliferation, DNA and RNA synthesis, etc. …”
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319
Mitoxantrone-Surfactant Interactions: A Physicochemical Overview
Published 2016-10-01“…As the cell membrane is the first barrier encountered by anticancer drugs before reaching the DNA sites inside the cells and as surfactant micelles are known as simple model systems for biological membranes, the drugs-surfactant interaction has been the subject of great research interest. …”
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320
α/β-Hydrolase Domain-Containing 6 (ABHD6)— A Multifunctional Lipid Hydrolase
Published 2022-08-01“…Here, we provide new insights into the experimentally derived crystal structure of ABHD6 and its possible orientation in biological membranes, and discuss ABHD6′s functions in health and disease.…”
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