Tunable ion transport through ultimately small channels by Hao Wang, Chongyang Yang, Shuo Wang, Sheng Hu

“…Biological membranes allow not only fast and selective ion permeation but also tunable ion transport, passively or actively on demands, in response to external stimuli such as light, voltage, temperature, etc. …”
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Novel Pyrimidine Derivatives as Potential Anticancer Agents: Synthesis, Biological Evaluation and Molecular Docking Study by Beata Tylińska, Benita Wiatrak, Żaneta Czyżnikowska, Aneta Cieśla-Niechwiadowicz, Elżbieta Gębarowska, Anna Janicka-Kłos

“…Tested compounds have more lipophilic character than doxorubicin, which determines their affinity for the molecular target and passive transport through biological membranes. Moreover, the inhibitory potential against topoisomerase II and DNA intercalating properties of synthesized compounds were analyzed via molecular docking.…”
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Steady-State and Time-Resolved Fluorescence Study of Selected Tryptophan-Containing Peptides in an AOT Reverse Micelle Environment by Krystian Gałęcki, Agnieszka Kowalska-Baron, Katarzyna E. Nowak, Anna Gajda, Beata Kolesińska

“…The aim of this study was to demonstrate the utility of time-resolved fluorescence spectroscopy in the detection of subtle changes in the local microenvironment of a tryptophan chromophore in a confined and crowded medium of AOT reverse micelles, which mimic biological membranes and cell compartmentalization. For this purpose, fluorescence properties of L-tryptophan and several newly synthesized tryptophan-containing peptides in buffer and in an AOT reverse micelle medium were determined. …”
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Efficient TGF-β1 Delivery to Articular Chondrocytes In Vitro Using Agro-Based Liposomes by Émilie Velot, Kamil Elkhoury, Cyril Kahn, Hervé Kempf, Michel Linder, Elmira Arab-Tehrany, Arnaud Bianchi

“…Naturally derived liposomes have been shown to be promising delivery nanosystems due to their similarities with biological membranes. Here, we used agro-based rapeseed liposomes, which contains a high level of mono- and poly-unsaturated fatty acids, to efficiently deliver encapsulated TGF-β1 to rat chondrocytes. …”
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Photoinduced bidirectional switching in lipid membranes containing azobenzene glycolipids by Jonas E. Warias, Franziska Reise, Svenja C. Hövelmann, Rajendra P. Giri, Michael Röhrl, Jule Kuhn, Malte Jacobsen, Kuntal Chatterjee, Thomas Arnold, Chen Shen, Sven Festersen, Andrea Sartori, Philipp Jordt, Olaf M. Magnussen, Thisbe K. Lindhorst, Bridget M. Murphy

“…Abstract Following the reaction of biological membranes to external stimuli reveals fundamental insights into cellular function. …”
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Polyphenolic Antioxidants in Lipid Emulsions: Partitioning Effects and Interfacial Phenomena by Marlene Costa, Sonia Losada-Barreiro, Fátima Paiva-Martins, Carlos Bravo-Díaz

“…The autoxidation of lipids in complex systems such as emulsions or biological membranes, although known to occur readily and to be associated with important pathological events, is lacking in quantitative data in spite of the huge efforts that have been made in attempting to unravel the complex mechanisms of lipid oxidation and its inhibition by antioxidants. …”
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Design X Bioinformatics: a community-driven initiative to connect bioinformatics and design by Sommer Björn, Inoue Daisuke, Baaden Marc

“…In addition, bioinformatics relates to many other areas, such as analysis of microscopic images (e.g., organelle localization), molecular modelling (e.g., proteins, biological membranes), and visualization of biological networks (e.g., protein–protein interaction networks, metabolism). …”
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Plasmalogen Replacement Therapy by José Carlos Bozelli, Richard M. Epand

“…Plasmalogens, a subclass of glycerophospholipids containing a vinyl-ether bond, are one of the major components of biological membranes. Changes in plasmalogen content and molecular species have been reported in a variety of pathological conditions ranging from inherited to metabolic and degenerative diseases. …”
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Exploring Barrier Mechanisms Relevant for Drug Therapy by Heidi Wunderli-Allenspach, Karsten Bucher, Jiri Hofmann, Marco Marenchino, Anita Thomae, Maja Günthert, Stefanie D. Krämer

“…Up to 500 different lipids have been reported to be present in different biological membranes. The origin and meaning of this diversity is not well understood. …”
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Ibuprofen in a Lipid Bilayer: Nanoscale Spatial Arrangement by Anna S. Kashnik, Denis S. Baranov, Sergei A. Dzuba

“…The findings shed new light on the nanoscale spatial arrangement of ibuprofen in biological membranes.…”
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The Ubiquitin–Proteasome System in Tumor Metabolism by Jie Wang, Yuandi Xiang, Mengqi Fan, Shizhen Fang, Qingquan Hua

“…In addition, fatty acids are harnessed to satisfy the increased requirement for the phospholipid components of biological membranes and energy. Moreover, the anabolism/catabolism of amino acids, such as glutamine, cystine, and serine, provides nitrogen donors for biosynthesis processes, development of the tumor inflammatory environment, and signal transduction. …”
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Enteral insufficiency syndrome: current provisions about the terminology, pathogenesis and treatment (review of literature) by S. A. Aliev, E. S. Aliev

“…According to new views, EDS is a combination of various pathogenetic mechanisms that are formed as a result of dysregulation and destabilization of biological membranes of tissue structures of the intestinal wall (especially its mucous membrane) and a violation of the functional and metabolic status of the intestine, developing in acute surgical diseases of the abdominal organs. …”
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Measuring sub-nanometer undulations at microsecond temporal resolution with metal- and graphene-induced energy transfer spectroscopy by Tao Chen, Narain Karedla, Jörg Enderlein

“…Abstract Out-of-plane fluctuations, also known as stochastic displacements, of biological membranes play a crucial role in regulating many essential life processes within cells and organelles. …”
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Physiological Cooperation between Aquaporin 5 and TRPV4 by Kata Kira Kemény, Eszter Ducza

“…Aquaporins—among them, AQP5—are responsible for transporting water across biological membranes, which is an important process in all living organisms. …”
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Key events in cancer: Dysregulation of SREBPs by Yunkuo Li, Shouwang Wu, Xiaodong Zhao, Shiming Hao, Faping Li, Yuxiong Wang, Bin Liu, Difei Zhang, Yishu Wang, Honglan Zhou

“…Cancer cells require high levels of lipid synthesis and uptake not only to support their continued replication, invasion, metastasis, and survival but also to participate in the formation of biological membranes and signaling molecules. Sterol regulatory element binding proteins (SREBPs) are core transcription factors that control lipid metabolism and the expression of important genes for lipid synthesis and uptake. …”
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Monitoring of Gold Biodistribution from Nanoparticles Using a HPLC-Visible Method by Thomas Chaigneau, Arnaud Pallotta, Fatima Zahra Benaddi, Lucie Sancey, Said Chakir, Ariane Boudier, Igor Clarot

“…Their possible small size (<10 nm) can lead to the crossing of biological membranes and then to problematic dissemination and storage in organs that must be controlled and evaluated. …”
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Lipids shape the electron acceptor-binding site of the peripheral membrane protein dihydroorotate dehydrogenase by Costeira-Paulo, J, Gault, J, Popova, G, Ladds, M, van Leeuwen, I, Sarr, M, Olsson, A, Lane, D, Laín, S, Marklund, E, Landreh, M

“…The interactions between proteins and biological membranes are important for drug development, but remain notoriously refractory to structural investigation. …”

Combined quantitative and mechanistic study of drug-membrane interactions using a novel 2H NMR approach. by Middleton, D, Reid, D, Watts, A

“…The (2)H NMR approach could be of value in guiding medicinal chemistry toward or away from structures promoting interactions with specific types of biological membranes.…”

Making a little affinity go a long way: a topological view of LFA-1 regulation. by Dustin, M

“…Interactions of adhesion molecules are governed by the law of mass action and the less understood rules of apposed biological membranes. Biochemical parameters such as adhesion molecule affinity only tell part of the story. …”

Review on fatty acid desaturases and their roles in temperature acclimatisation by Garba, Lawal, Mohamad Ali, Mohd Shukuri, Oslan, Siti Nurbaya, Raja Abdul Rahman, Raja Noor Zaliha

“…Most fatty acids especially the so-called polyunsaturated fatty acids (PUFAs) and their derivatives play key biological roles in inflammatory response, cell division, control of lipid metabolism, as signaling molecules, supply of energy and protecting the biological membranes structure and function. In this study, a general overview of fatty acids, their biosynthesis mechanisms as well as biological importance have been discussed. …”
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