Selective Moonlighting Cell-Penetrating Peptides by Rafael Morán-Torres, David A. Castillo González, Maria Luisa Durán-Pastén, Beatriz Aguilar-Maldonado, Susana Castro-Obregón, Gabriel Del Rio

“…Cell penetrating peptides (CPPs) are molecules capable of passing through biological membranes. This capacity has been used to deliver impermeable molecules into cells, such as drugs and DNA probes, among others. …”
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A Comparative Study of PMETAC-Modified Mesoporous Silica and Titania Thin Films for Molecular Transport Manipulation by Sebastian Alberti, Juan Giussi, Omar Azzaroni, Galo J. A. A. Soler-Illia

“…The manipulation and understanding of molecular transport across functionalized nanopores will take us closer to mimicking biological membranes and thus to design high-performance permselective separation systems. …”
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A common human MLKL polymorphism confers resistance to negative regulation by phosphorylation by Sarah E. Garnish, Katherine R. Martin, Maria Kauppi, Victoria E. Jackson, Rebecca Ambrose, Vik Ven Eng, Shene Chiou, Yanxiang Meng, Daniel Frank, Emma C. Tovey Crutchfield, Komal M. Patel, Annette V. Jacobsen, Georgia K. Atkin-Smith, Ladina Di Rago, Marcel Doerflinger, Christopher R. Horne, Cathrine Hall, Samuel N. Young, Matthew Cook, Vicki Athanasopoulos, Carola G. Vinuesa, Kate E. Lawlor, Ian P. Wicks, Gregor Ebert, Ashley P. Ng, Charlotte A. Slade, Jaclyn S. Pearson, André L. Samson, John Silke, James M. Murphy, Joanne M. Hildebrand

“…Here we show that this substitution confers a gain in necroptotic function in human cells, with more rapid accumulation of activated MLKLS132P in biological membranes and MLKLS132P overriding pharmacological and endogenous inhibition of MLKL. …”
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Structures, Mechanisms, and Physiological Functions of Zinc Transporters in Different Biological Kingdoms by Han Ba Bui, Kenji Inaba

“…Zinc transporters take up/release zinc ions (Zn²⁺) across biological membranes and maintain intracellular and intra-organellar Zn²⁺ homeostasis. …”
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Cholesterol Interaction Directly Enhances Intrinsic Activity of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) by Stephanie Chin, Mohabir Ramjeesingh, Maurita Hung, June Ereño-Oreba, Hong Cui, Onofrio Laselva, Jean-Philippe Julien, Christine E. Bear

“…Interestingly, despite predictions based on channel activity measurements in biological membranes, the structure of the detergent purified, phosphorylated, and ATP-bound human CFTR protein did not reveal a stably open conduction pathway. …”
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Oxidative Stress and Dietary Fat Type in Relation to Periodontal Disease by Alfonso Varela-López, José L. Quiles, Mario Cordero, Francesca Giampieri, Pedro Bullón

“…In addition, dietary fatty acid intake influences in relative fatty acid composition of biological membranes determining its susceptibility to oxidative alterations. …”
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Analysis of the Mercury Content in Fish for Human Consumption in Poland by Barbara Brodziak-Dopierała, Agnieszka Fischer

“…Organic Hg derivatives readily penetrate biological membranes and pose a particular health risk. Food of aquatic origin is the main source of human exposure to methylmercury (MeHg). …”
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Assessing the Role of Aquaporin 4 in Skeletal Muscle Function by Tejal Aslesh, Ammar Al-aghbari, Toshifumi Yokota

“…Water transport across the biological membranes is mediated by aquaporins (AQPs). AQP4 and AQP1 are the predominantly expressed AQPs in the skeletal muscle. …”
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Nanoparticles Modified with Cell-Penetrating Peptides: Conjugation Mechanisms, Physicochemical Properties, and Application in Cancer Diagnosis and Therapy by Isabel Gessner, Ines Neundorf

“…CPPs are often cationic peptide sequences that are able to translocate across biological membranes and to carry attached cargos inside cells and have thus been recognized as versatile tools for drug delivery. …”
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Signal Transduction across the Nuclear Envelope: Role of the LINC Complex in Bidirectional Signaling by Miki Hieda

“…To reach the nucleus, an extracellular signal must be transmitted across three biological membranes: the plasma membrane, as well as the inner and outer nuclear membranes. …”
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Microemulsion-Based Media in Nose-to-Brain Drug Delivery by Anna Froelich, Tomasz Osmałek, Barbara Jadach, Vinam Puri, Bozena Michniak-Kohn

“…Microemulsions as potential drug delivery systems offer good solubilizing properties and the ability to enhance drug permeation through biological membranes. The aim of this review is to summarize the current status of the research focused on microemulsion-based systems for nose-to-brain delivery with special attention to the most extensively investigated neurological and psychiatric conditions, such as neurodegenerative diseases, epilepsy, and schizophrenia.…”
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Effect of Dielectric Barrier Discharge Plasma against <i>Listeria monocytogenes</i> Mixed-Culture Biofilms on Food-Contact Surfaces by Min Gyu Song, Pantu Kumar Roy, Eun Bi Jeon, So Hee Kim, Min Soo Heu, Jung-Suck Lee, Jae-Suk Choi, Jin-Soo Kim, Shin Young Park

“…Field emission scanning electron microscopy (FE-SEM) demonstrated that DBD plasma cuts off intercellular contact and induces cell decomposition to prevent the development of biological membranes. It was confirmed that the formed biofilms collapsed and separated into individual bacteria. …”
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Aquaporins and Animal Gamete Cryopreservation: Advances and Future Challenges by João C. Ribeiro, David F. Carrageta, Raquel L. Bernardino, Marco G. Alves, Pedro F. Oliveira

“…Aquaporins (AQPs) constitute a family of channel proteins responsible for the transport of water, small solutes, and certain gases across biological membranes. Thirteen homologs of AQPs (AQP0-12) have been described. …”
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Structure and dynamics of an archetypal DNA nanoarchitecture revealed via cryo-EM and molecular dynamics simulations by Katya Ahmad, Abid Javed, Conor Lanphere, Peter V. Coveney, Elena V. Orlova, Stefan Howorka

“…Here we analyse an archetypal six-duplex DNA nanoarchitecture with single-particle cryo-electron microscopy and molecular dynamics simulations in solvents of tunable ionic strength and within the anisotropic environment of biological membranes. Outside lipid bilayers, the six-duplex bundle lacks the designed symmetrical barrel-type architecture. …”
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Optimization of cryo-electron microscopy for quantitative analysis of lipid bilayers by Frederick A. Heberle, Doug Welsch, Haden L. Scott, M. Neal Waxham

“…We recently showed that cryo-EM can be used to measure the bilayer thickness of lipid vesicles and biological membranes with subangstrom precision, resulting in the direct visualization of nanoscopic domains of different thickness in multicomponent lipid mixtures and giant plasma membrane vesicles. …”
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Peripheral Groups of Dicationic Pyrazinoporphyrins Regulate Lipid Membrane Binding by Daria A. Polivanovskaia, Anna N. Konstantinova, Kirill P. Birin, Valerij S. Sokolov, Oleg V. Batishchev, Yulia G. Gorbunova

“…Thus, this study reveals a new way to tune the PDT activity of PSs in biological membranes through designing the structure of the peripheral groups in the macrocyclic photosensitizer.…”
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The Application of Prodrugs as a Tool to Enhance the Properties of Nucleoside Reverse Transcriptase Inhibitors by Lívia da Rocha Fernandes, Juliana Romano Lopes, Andressa Francielli Bonjorno, João Lucas Bruno Prates, Cauê Benito Scarim, Jean Leandro Dos Santos

“…We comprehensively described various strategies that are used to enhance factors such as water solubility, bioavailability, pharmacokinetic parameters, permeability across biological membranes, chemical stability, drug delivery to specific sites/organs, and tolerability. …”
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AQP3 Facilitates Proliferation and Adipogenic Differentiation of Porcine Intramuscular Adipocytes by Xiaoyu Wang, Jing Yang, Ying Yao, Xin’E Shi, Gongshe Yang, Xiao Li

“…Aquaglyceroporin (AQP) defines a class of water/glycerol channels that primarily facilitate the passive transport of glycerol and water across biological membranes. In this study, the AQP3 protein of the AQP family was mainly studied in the adipogenic function of intramuscular adipocytes in pigs. …”
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Manganese ion gradient liposomes modified by disulfide bond enhance cellular uptake and tumor immunity by Chang Peng, Ming Zhao, Xuan Wang, Min Yan, Yanyan Han, Dawei Chen, Haiyang Hu

“…However, due to their high positive charge, manganese ions cannot freely penetrate biological membranes, and it is challenging to target them to the cells. …”
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Inhibitors of the Sec61 Complex and Novel High Throughput Screening Strategies to Target the Protein Translocation Pathway by Eva Pauwels, Ralf Schülein, Kurt Vermeire

“…Proteins targeted to the secretory pathway start their intracellular journey by being transported across biological membranes such as the endoplasmic reticulum (ER). …”
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