Spectral Characteristics and Functional Responses of Phospholipid Bilayers in the Terahertz Band by Yanyun Lin, Xingjuan Wu, Kaicheng Wang, Sen Shang, Yubin Gong, Hongwei Zhao, Dai Wu, Peng Zhang, Xiaoyun Lu

“…This study investigated several important phospholipid components of biological membranes—distearoyl phosphatidylethanolamine (DSPE), dipalmitoyl phosphatidylcholine (DPPC), sphingosine phosphorylcholine (SPH), and lecithin bilayer—using THz time-domain spectroscopy. …”
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The Secret Lives of Fluorescent Membrane Probes as Revealed by Molecular Dynamics Simulations by Hugo A. L. Filipe, Maria João Moreno, Luís M. S. Loura

“…Fluorescent probes have been employed for more than half a century to study the structure and dynamics of model and biological membranes, using spectroscopic and/or microscopic experimental approaches. …”
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Nanoparticles of <i>N</i>-Vinylpyrrolidone Amphiphilic Copolymers and Pheophorbide <i>a</i> as Promising Photosensitizers for Photodynamic Therapy: Design, Properties and In Vitro... by Alexander Yu. Rybkin, Svetlana V. Kurmaz, Elizaveta A. Urakova, Natalia V. Filatova, Lev R. Sizov, Alexey V. Kozlov, Mikhail O. Koifman, Nikolai S. Goryachev

“…However, its aggregation degree decreases sharply, and singlet oxygen quantum yield and the fluorescence signal increase upon the interaction of these NPs with model biological membranes—liposomes or components of a tissue homogenate. …”
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P-Type ATPase Apt1 of the Fungal Pathogen <i>Cryptococcus neoformans</i> Is a Lipid Flippase of Broad Substrate Specificity by Lyubomir Dimitrov Stanchev, Juliana Rizzo, Rebecca Peschel, Lilli A. Pazurek, Lasse Bredegaard, Sarina Veit, Sabine Laerbusch, Marcio L. Rodrigues, Rosa L. López-Marqués, Thomas Günther Pomorski

“…Lipid flippases of the P4-ATPase family are ATP-driven transporters that translocate lipids from the exoplasmic to the cytosolic leaflet of biological membranes. In the encapsulated fungal pathogen <i>Cryptococcus neoformans</i>, the P4-ATPase Apt1p is an important regulator of polysaccharide secretion and pathogenesis, but its biochemical characterization is lacking. …”
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Human erythrocytes as pharmacological biomodel of antioxidant cytoprotection for the evaluation of new therapeutic alternatives in patients with COVID-19 by Yoandra Mora Tassé, Onel Fong Lores, Clara Azalea Berenguer Rivas, Irela Yolaidys Pérez Andrés

“…Introduction: The oxidative stress can affect the biological membranes of different cellular types in the organism, which has been evidenced in the damages to the tissues and organs of patients with COVID-19, reason why the recent investigations are related to the search of cytoprotector and antioxidant drugs that minimize these damages.  …”
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Building Asymmetric Lipid Bilayers for Molecular Dynamics Simulations: What Methods Exist and How to Choose One? by Emily H. Chaisson, Frederick A. Heberle, Milka Doktorova

“…The compositional asymmetry of biological membranes has attracted significant attention over the last decade. …”
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In Vitro Interactions of Amphiphilic Phosphorous Dendrons with Liposomes and Exosomes—Implications for Blood Viscosity Changes by Martina Veliskova, Milan Zvarik, Simon Suty, Juraj Jacko, Patrick Mydla, Katarina Cechova, Daniela Dzubinska, Marcela Morvova, Maksim Ionov, Maria Terehova, Jean-Pierre Majoral, Maria Bryszewska, Iveta Waczulikova

“…To characterize the nature of the interactions among blood components and dendrons, we performed experiments on the liposomes and exosomes as models of biological membranes. Based on results obtained using diverse biophysical methods, we conclude that the interactions were of electrostatic nature. …”
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Lutein and Zeaxanthin Content in 21 Plant Species from a Very Humid Premontane Forest in Colombia Palatable for Free-Range Laying Hens by Yandy J. Aguillón-Páez, Gonzalo J. Díaz

“…Xanthophylls, such as lutein and zeaxanthin, have several functions in both plants and humans, including detoxification of oxidants (reactive oxygen species (ROS) and other radicals), maintenance of the structural and functional integrity of biological membranes, and photoprotection from intense light damage. …”
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Long-Lasting, Antinociceptive Effects of pH-Sensitive Niosomes Loaded with Ibuprofen in Acute and Chronic Models of Pain by Francesca Marzoli, Carlotta Marianecci, Federica Rinaldi, Daniele Passeri, Marco Rossi, Paola Minosi, Maria Carafa, Stefano Pieretti

“…NSAIDs encounter several obstacles to passing across biological membranes. To overcome these constraints, we decided to study the effects of a new pH-sensitive formulation of niosomes containing Polysorbate 20 derivatized by Glycine and loaded with ibuprofen (NioIbu) in several animal models of pain in mice. …”
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Miscibility of Phosphatidylcholines in Bilayers: Effect of Acyl Chain Unsaturation by Agata Żak, Natan Rajtar, Waldemar Kulig, Mariusz Kepczynski

“…The miscibility of phospholipids in a hydrated bilayer is an issue of fundamental importance for understanding the organization of biological membranes. Despite research on lipid miscibility, its molecular basis remains poorly understood. …”
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Preformulation Studies of Novel Menthol Prodrugs with Antiparasitic Activity: Chemical Stability, In Silico, and In Vitro Permeability Assays by Camila M. Clemente, Renée Onnainty, Nadina Usseglio, Gladys E. Granero, Soledad Ravetti

“…Permeability studies conducted in silico predicted that both menthol and its prodrugs would pass through biological membranes via flip-flop movement. This prediction was subsequently confirmed by in vitro BAM permeability studies, where it was observed that the menthol prodrugs (<b>1c</b> and <b>1g</b>) exhibited the highest P_app (apparent permeability) value compared to the parent compound. …”
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Brownian Aging as One of the Mechanistic Components That Shape the Single-Channel Ionic Currents through Biological and Synthetic Membranes by Agata Wawrzkiewicz-Jałowiecka, Andrzej Fuliński

“…This observation may be valuable in technical uses of nanochannels in synthetic membranes and allow for a better understanding of the reason for the differences between the biochannels’ activity in diverse biological membranes. Proposals of experimental verification of this aging O/C hypothesis are also presented.…”
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Mitochondrial Cyclosporine A-Independent Palmitate/Ca²⁺-Induced Permeability Transition Pore (PA-mPT Pore) and Its Role in Mitochondrial Function and Protection against... by Galina D. Mironova, Evgeny V. Pavlov

“…In the paper, we discuss conditions of its opening in the biological membranes, as well as its role in the physiological and pathophysiological processes. …”
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Current Trends and Changes in Use of Membrane Molecular Dynamics Simulations within Academia and the Pharmaceutical Industry by Stephan L. Watkins

“…Many of these are focused on neurological membranes, and biological membranes in general, applied to the medical industry. …”
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PoreWalker: a novel tool for the identification and characterization of channels in transmembrane proteins from their three-dimensional structure. by Marialuisa Pellegrini-Calace, Tim Maiwald, Janet M Thornton

“…Transmembrane channel proteins play pivotal roles in maintaining the homeostasis and responsiveness of cells and the cross-membrane electrochemical gradient by mediating the transport of ions and molecules through biological membranes. Therefore, computational methods which, given a set of 3D coordinates, can automatically identify and describe channels in transmembrane proteins are key tools to provide insights into how they function.Herein we present PoreWalker, a fully automated method, which detects and fully characterises channels in transmembrane proteins from their 3D structures. …”
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Dual Action of the PN159/KLAL/MAP Peptide: Increase of Drug Penetration across Caco-2 Intestinal Barrier Model by Modulation of Tight Junctions and Plasma Membrane Permeability by Alexandra Bocsik, Ilona Gróf, Lóránd Kiss, Ferenc Ötvös, Ottó Zsíros, Lejla Daruka, Lívia Fülöp, Monika Vastag, Ágnes Kittel, Norbert Imre, Tamás A. Martinek, Csaba Pál, Piroska Szabó-Révész, Mária A. Deli

“…PN159, also known as KLAL or MAP, was described to interact with biological membranes as a cell-penetrating peptide. In the present work we demonstrated that the PN159 peptide as a penetration enhancer has a dual action on intestinal epithelial cells. …”
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Out-of-equilibrium mechanochemistry and self-organization of fluid membranes interacting with curved proteins by Caterina Tozzi, Nikhil Walani, Marino Arroyo

“…The function of biological membranes is controlled by the interaction of the fluid lipid bilayer with various proteins, some of which induce or react to curvature. …”
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Effects of Detergent on α-Synuclein Structure: A Native MS-Ion Mobility Study by Rani Moons, Renate van der Wekken-de Bruijne, Stuart Maudsley, Filip Lemière, Anne-Marie Lambeir, Frank Sobott

“…Using different types of detergents to mimic lipid molecules present in biological membranes, including the presence of Ca²⁺ ions as an important structural factor, we aimed to gain an understanding of how α-synuclein interacts with membrane models and how this affects the protein conformation and potential oligomerization. …”
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Impact of humic acids on EYL liposome membranes: ESR method by Pytel Barbara, Filipiak Aneta, Pisarek Izabella, Olchawa Ryszard, Man Dariusz

“…This effect may be related to the complexation of xenobiotics present in the soil environment and their impact on biological membranes.…”
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Altered Sphingolipids Metabolism Damaged Mitochondrial Functions: Lessons Learned From Gaucher and Fabry Diseases by Margarita Ivanova

“…Sphingolipids represent a class of bioactive lipids that modulate the biophysical properties of biological membranes and play a critical role in cell signal transduction. …”
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