The SARS-CoV-2 host cell receptor ACE2 correlates positively with immunotherapy response and is a potential protective factor for cancer progression by Zhilan Zhang, Lin Li, Mengyuan Li, Xiaosheng Wang

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Improving the Diagnosis of Phenylketonuria by Using a Machine Learning–Based Screening Model of Neonatal MRM Data by Zhixing Zhu, Zhixing Zhu, Jianlei Gu, Jianlei Gu, Jianlei Gu, Georgi Z. Genchev, Georgi Z. Genchev, Georgi Z. Genchev, Xiaoshu Cai, Xiaoshu Cai, Yangmin Wang, Jing Guo, Guoli Tian, Hui Lu, Hui Lu, Hui Lu

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PD-1 gene polymorphisms and thyroid expression of PD-1 ligands differ between Graves’ and Hashimoto’s diseases by Mayumi Kawabata, Naoya Inoue, Mikio Watanabe, Ayaka Kobayashi, Yoh Hidaka, Akira Miyauchi, Yoshinori Iwatani

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Genetic Interactions with Intrauterine Diabetes Exposure in Relation to Obesity: The EPOCH and Project Viva Studies by Maggie A. Stanislawski, Elizabeth Litkowski, Ruby Fore, Sheryl L. Rifas-Shiman, Emily Oken, Marie-France Hivert, Ethan M. Lange, Leslie A. Lange, Dana Dabelea, Sridharan Raghavan

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graph-GPA 2.0: improving multi-disease genetic analysis with integration of functional annotation data by Qiaolan Deng, Arkobrato Gupta, Hyeongseon Jeon, Hyeongseon Jeon, Jin Hyun Nam, Ayse Selen Yilmaz, Won Chang, Maciej Pietrzak, Lang Li, Hang J. Kim, Dongjun Chung, Dongjun Chung

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Social Media Use in Higher Education: A Review by Georgios Zachos, Efrosyni-Alkisti Paraskevopoulou-Kollia, Ioannis Anagnostopoulos

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A model-agnostic approach for understanding heart failure risk factors by Seyed M. Miran, Stuart J. Nelson, Qing Zeng-Treitler

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E pluribus unum interpretable convolutional neural networks by George Dimas, Eirini Cholopoulou, Dimitris K. Iakovidis

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FiNGS: high quality somatic mutations using filters for next generation sequencing by Christopher Paul Wardell, Cody Ashby, Michael Anton Bauer

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Conceiving an application ontology to model patient human papillomavirus vaccine counseling for dialogue management by Muhammad Amith, Kirk Roberts, Cui Tao

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Breast Cancer Stem Cells: Biomarkers, Identification and Isolation Methods, Regulating Mechanisms, Cellular Origin, and Beyond by Xiaoli Zhang, Kimerly Powell, Lang Li

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Long non-coding RNAs as a source of new peptides by Jorge Ruiz-Orera, Xavier Messeguer, Juan Antonio Subirana, M Mar Alba

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Presence of complete murine viral genome sequences in patient-derived xenografts by Zihao Yuan, Xuejun Fan, Jay-Jiguang Zhu, Tong-Ming Fu, Jiaqian Wu, Hua Xu, Ningyan Zhang, Zhiqiang An, W. Jim Zheng

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User Analytics in Online Social Networks: Evolving from Social Instances to Social Individuals by Gerasimos Razis, Stylianos Georgilas, Giannis Haralabopoulos, Ioannis Anagnostopoulos

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Radiomic tumor phenotypes augment molecular profiling in predicting recurrence free survival after breast neoadjuvant chemotherapy by Rhea Chitalia, Marios Miliotis, Nariman Jahani, Spyros Tastsoglou, Elizabeth S. McDonald, Vivian Belenky, Eric A. Cohen, David Newitt, Laura J. van’t Veer, Laura Esserman, Nola Hylton, Angela DeMichele, Artemis Hatzigeorgiou, Despina Kontos

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An automated method for segmenting white matter lesions through multi-level morphometric feature classification with application to lupus by Mark Scully, Mark Scully, Blake Anderson, Terran Lane, Charles Gasparovic, Charles Gasparovic, Vince Magnotta, Wilmer Sibbitt, Carlos Roldan, Ron Kikinis, Henry Jeremy Bockholt, Henry Jeremy Bockholt

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Identifying shared genetic architecture between rheumatoid arthritis and other conditions: a phenome-wide association study with genetic risk scoresResearch in context by Harrison G. Zhang, Greg McDermott, Thany Seyok, Sicong Huang, Kumar Dahal, Sehi L’Yi, Clara Lea-Bonzel, Jacklyn Stratton, Dana Weisenfeld, Paul Monach, Soumya Raychaudhuri, Kun-Hsing Yu, Tianrun Cai, Jing Cui, Chuan Hong, Tianxi Cai, Katherine P. Liao

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Editorial: Blockchain and distributed ledger technology—enabled architectures for improving healthcare by Tsung-Ting Kuo, Tsung-Ting Kuo, Peng Zhang, Peng Zhang

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What prevents us from reusing medical real-world data in research by Julia Gehrmann, Edit Herczog, Stefan Decker, Oya Beyan

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Knowledge Representation in Patient Safety Reporting: An Ontological Approach by Liang Chen, Gong Yang

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