Pre-Cambrian to Palaeozoic Palaeopalynology and Palaeobotany by Steemans Philippe, Javaux Emmanuelle

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Whole blood transcriptional profiles as a prognostic tool in complete and incomplete Kawasaki Disease. by Preeti Jaggi, Asuncion Mejias, Zhaohui Xu, Han Yin, Melissa Moore-Clingenpeel, Bennett Smith, Jane C Burns, Adriana H Tremoulet, Alejandro Jordan-Villegas, Damien Chaussabel, Karen Texter, Virginia Pascual, Octavio Ramilo

“…CONCLUSION:A reproducible biosignature from KD patients was identified, and was similar in children with cKD and inKD. …”
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Isotopes as a Tool for Exploring Exoplanet Atmospheres by Glidden, Ana

“…I also extend this to the detectability of novel biosignature gases by way of carbon isotope ratios. …”
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The future of spectroscopic life detection on exoplanets by Seager, Sara

“…Life can be inferred by the presence of atmospheric biosignature gases—gases produced by life that can accumulate to detectable levels in an exoplanet atmosphere. …”
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Novel Phospholipid Signature of Depressive Symptoms in Patients With Coronary Artery Disease by Parco Chan, Ivonne Suridjan, Dana Mohammad, Nathan Herrmann, Graham Mazereeuw, Lyn M. Hillyer, David W. L. Ma, Paul I. Oh, Krista L. Lanctôt

“…Phospholipid species were selected using partial least‐square discriminant analysis, and the ability of the resulting model to discriminate between groups was evaluated using receiver operator characteristic curves. Biosignature scores were calculated from this model, and analyses of covariance were performed to compare intergroup differences in biosignature scores, with adjustment for clinical differences between patients. …”
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Photosynthesis in Hydrogen-Dominated Atmospheres by William Bains, Sara Seager, Andras Zsom

“…Ammonia is a potential biosignature gas of hydrogenic photosynthesis that is unlikely to be generated abiologically. …”
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Laboratory studies on the viability of life in H2-dominated exoplanet atmospheres by Seager, Sara, Huang, Jin, Petkowski, Janusz Jurand, Pajusalu, Mihkel

“…Theory and observation for the search for life on exoplanets via atmospheric ‘biosignature gases’ is accelerating, motivated by the capabilities of the next generation of space- and ground-based telescopes. …”
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Photosynthesis in Hydrogen-Dominated Atmospheres by Bains, William, Seager, Sara, Zsom, Andras

“…Ammonia is a potential biosignature gas of hydrogenic photosynthesis that is unlikely to be generated abiologically. …”
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Identification of surrogates of protection against yersiniosis in immersion vaccinated Atlantic salmon. by Andrew R Bridle, Ben F Koop, Barbara F Nowak

“…This biosignature may be used as a surrogate of protection and therefore as a predictor of vaccine success against yersiniosis.…”
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A Combinatorial Approach to Biochemical Space: Description and Application to the Redox Distribution of Metabolism by Bains, William, Seager, Sara

“…These potential biosignature gases may differ from energy-capture redox biosignatures. …”
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Use of NanoSIMS in the search for early life on Earth: ambient inclusion trails in a c. 3400 Ma sandstone by Wacey, D, Kilburn, MR, McLoughlin, N, Parnell, J, Stoakes, C, Grovenor, C, Brasier, M

“…AIT may hold potential as a biosignature for investigating early life on Earth if the associated organic material can be shown to be biological, This paper attempts to test the formation mechanism and biogenicity of AIT from the c. 3400 Ma Strelley Pool sandstone of Western Australia using NanoSIMS technology. …”

Habitability and sub glacial liquid water on planets of M-dwarf stars by Amri Wandel

“…A new study shows that subglacial melting may provide an answer, significantly extending the habitability region, in particular around M-dwarf stars, which are also the most promising for biosignature detection with the present and near-future technology.…”
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Dysregulated Immune Activation in Second-Line HAART HIV+ Patients Is Similar to That of Untreated Patients. by Milena S Espíndola, Leonardo J G Lima, Luana S Soares, Maira C Cacemiro, Fabiana A Zambuzi, Matheus de Souza Gomes, Laurence R Amaral, Valdes R Bollela, Olindo A Martins-Filho, Fabiani G Frantz

“…CONCLUSION:HIV patients in different HAART regimens develop distinct immunological biosignature, introducing a novel perspective into disease outcome and potential new therapies that consider HAART patients as a heterogeneous group.…”
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Possibilities for an Aerial Biosphere in Temperate Sub Neptune-Sized Exoplanet Atmospheres by Seager, Sara, Petkowski, Janusz J., Günther, Maximilian N., Bains, William, Mikal-Evans, Thomas, Deming, Drake

“…The search for signs of life through the detection of exoplanet atmosphere biosignature gases is gaining momentum. Yet, only a handful of rocky exoplanet atmospheres are suitable for observation with planned next-generation telescopes. …”
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Biogenic calcium carbonate as evidence for life by S. Ronca, F. Mura, M. Brandano, A. Cirigliano, F. Benedetti, A. Grottoli, M. Reverberi, D. F. Maras, R. Negri, E. Di Mauro, T. Rinaldi

“…The calcite moonmilk is the only known carbonate speleothem on Earth with undoubted biogenic origin, thus representing a robust and credible biosignature of life. Its presence in the inner parts of rocks adds to its characteristics as a biosignature.…”
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Prediction of the Immune Phenotypes of Bladder Cancer Patients for Precision Oncology by Hyuna Cho, Feng Tong, Sungyong You, Sungyoung Jung, Won Hwa Kim, Jayoung Kim

“…This study aimed to develop a biosignature of immunotherapy-based responses using gene expression data. …”
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Omics-CNN: A comprehensive pipeline for predictive analytics in quantitative omics using one-dimensional convolutional neural networks by Anastasia Zompola, Aigli Korfiati, Konstantinos Theofilatos, Seferina Mavroudi

“…Results: The newly introduced pipeline was applied to one transcriptomics and one proteomics dataset for the identification of diagnostic models and biosignatures for Ischemic Stroke (IS) and COVID-19 infection, reporting highly accurate biosignatures with accuracies of 96 % and 95.41 %, respectively. …”
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Potential of Host Serum Protein Biomarkers in the Diagnosis of Tuberculous Meningitis in Children by Charles M. Manyelo, Regan S. Solomons, Candice I. Snyders, Hygon Mutavhatsindi, Portia M. Manngo, Kim Stanley, Gerhard Walzl, Novel N. Chegou

“…A new childhood TBM specific 3-marker biosignature (adipsin, Aβ42, and IL-10) showed potential in the diagnosis of TBM, with AUC of 0.84 (95% CI, 0.73–0.96), sensitivity of 82.6% (95 CI, 61.2–95.0%) and specificity of 75.0% (95% CI, 53.3–90.2%) after leave-one-out cross validation.Conclusion: A previously described adult 7-marker serum protein biosignature showed potential in the diagnosis of TBM in children. …”
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Molecular medicine-based IBD treatment strategies—we take it personally! by Viktoria Hentschel, Jochen Klaus

“…To solve this therapeutic dichotomy, there is a pressing need for a reliable classification of patients based on their biosignature to rate their individual prognosis and likelihood of response to a given therapy. …”
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Oligotrophic Growth of Nitrate-Dependent Fe2+-Oxidising Microorganisms Under Simulated Early Martian Conditions by Alex Price, Michael C. Macey, Victoria K. Pearson, Susanne P. Schwenzer, Nisha K. Ramkissoon, Karen Olsson-Francis

“…This can guide missions in identifying palaeoenvironments of interest for biosignature detection. Indeed, biomineralised cells identified on the olivine surface provide a previously unexplored mechanism for the preservation of morphological biosignatures in the martian geological record.…”
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