A review of electroencephalographic changes in diabetes mellitus in relation to major depressive disorder by Baskaran A, Milev R, McIntyre RS

“…In this review we will discuss EEG abnormalities in DM, as well as the biological mechanisms underlying various EEG parameters, in order to evaluate whether or not a common EEG biosignature exists between DM and MDD. Identifying such commonalities could significantly inform the current understanding of the mechanisms that subserve the development of the two conditions. …”
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Spectra of Earth-like planets through geological evolution around FGKM stars by Rugheimer, S, Kaltenegger, L

“…We find that the observability of biosignature gases reduces with increasing cloud cover and increases with planetary age. …”

Past and Present Approaches to Diagnosis of Active Pulmonary Tuberculosis by Anna Ritah Namuganga, Anna Ritah Namuganga, Anna Ritah Namuganga, Novel N. Chegou, Harriet Mayanja-Kizza, Harriet Mayanja-Kizza

“…In this review we found out that enormous biosignature research is ongoing to identify host biomarkers that can be used as predictors of active PTB disease. …”
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Productivity and Community Composition of Low Biomass/High Silica Precipitation Hot Springs: A Possible Window to Earth’s Early Biosphere? by Jeff R. Havig, Trinity L. Hamilton

“…Our data suggest productivity in Archean terrestrial hot springs may be directly linked to redox substrate availability, and there may be high potential for geochemical and physical biosignature preservation from these communities.…”
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Raman spectroscopic peculiarities of Icelandic poorly crystalline minerals and their implications for Mars exploration by Victoria Muñoz-Iglesias, Laura Sánchez-García, Daniel Carrizo, Antonio Molina, Maite Fernández-Sampedro, Olga Prieto-Ballesteros

“…The detection of silica is singularly interesting since, on the one hand, it can imply the past existence of hydrothermal hot springs rich in nutrient and redox gradients and, on the other hand, provides excellent matrix for biosignature preservation. The data can be helpful as an astrobiological database for the forthcoming missions to Mars, where potential upwelling groundwater systems could have altered the mineral phases in a similar way to that observed in this work.…”
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Phosphine on Venus Cannot Be Explained by Conventional Processes by Bains, William, Petkowski, Janusz J, Seager, Sara, Ranjan, Sukrit, Sousa-Silva, Clara, Rimmer, Paul B, Zhan, Zhuchang, Greaves, Jane S, Richards, Anita MS

“…Our analysis provides a template for investigation of phosphine as a biosignature on other worlds.…”
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Finding signs of life on Earth-like planets: high-resolution transmission spectra of Earth through time around FGKM stars by Kaltenegger, L, Lin, Z, Rugheimer, S

“…Assessing biosignatures and water on such planets orbiting hotter stars than the Sun will be extremely challenging even for high-resolution observations. …”

Fully fluorinated non-carbon compounds NF3 and SF6 as ideal technosignature gases by Sara Seager, Janusz J. Petkowski, Jingcheng Huang, Zhuchang Zhan, Sai Ravela, William Bains

“…NF3 and SF6 may be universal technosignatures owing to their special industrial properties, which unlike biosignature gases, are not species-dependent. Other key relevant qualities of NF3 and SF6 are: their extremely low water solubility, unique spectral features, and long atmospheric lifetimes. …”
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Ex Vivo Evaluation of Mucosal Responses to Vaccination with ALVAC and AIDSVAX of Non-Human Primates by Carolina Herrera, Ronald Veazey, Melissa M. Lemke, Kelly Arnold, Jerome H. Kim, Robin J. Shattock

“…The cytokine secretome revealed differences between vaccination with ALVAC and ALVAC/AIDSVAX not previously observed in mucosal tissues and distinct from the systemic response, which could represent a biosignature of the vaccine combination.…”
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Distinct inflammatory profile underlies pathological increases in creatinine levels associated with Plasmodium vivax malaria clinical severity. by Luís A B Cruz, Manoel Barral-Netto, Bruno B Andrade

“…IFN-γ/IL-10 ratio and CRP values marked the immune biosignature of vivax malaria patients, and could distinguish subjects with elevated creatinine levels who did not survive from those who did. …”
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Atmospheric oxygenation of the early earth and earth-like planets driven by competition between land and seafloor weathering by Yasuto Watanabe, Eiichi Tajika

“…Abstract Oxygen is a potential biosignature for terrestrial Earth-like planets. The primary source of oxygen on Earth is oxygenic photosynthesis, which may be limited by the supply of riverine phosphorus. …”
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Identification of host biomarkers from dried blood spots for monitoring treatment response in extrapulmonary tuberculosis by Shizza Khalid, Atiqa Ambreen, Aasia Khaliq, Hafeez Ullah, Manal Mustafa, Tehmina Mustafa

“…CXCL9/MIG, CCL20, CCL23, CXCL10/IP-10, CXCL1, CXCL2, and CXCL8 significantly declined in our cohort of EPTB (48 TB pleuritis and 57 TB lymphadenitis) patients at both time points. A biosignature consisting of MIG, CCL23, and CXCL2, corresponded with the treatment response in 81% of patients in the 2nd month and 79% of patients at the end of treatment. …”
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A Photon Force and Flow for Dissipative Structuring: Application to Pigments, Plants and Ecosystems by Karo Michaelian, Ramón Eduardo Cano Mateo

“…We propose using the wavelength dependence of global entropy production as a biosignature for discovering life on planets of other stars.…”
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Effect of Multiple Scattering on the Transmission Spectra and the Polarization Phase Curves for Earth-like Exoplanets by Manika Singla, Aritra Chakrabarty, Sujan Sengupta

“…It is the most appropriate time to characterize the Earth-like exoplanets in order to detect biosignature beyond the Earth because such exoplanets will be the prime targets of big-budget missions like JWST, Roman Space Telescope, HabEx, LUVOIR, Thirty Meter Telescope, Extremely Large Telescope, etc. …”
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In situ measurement and sampling of acidic alteration products at Río Tinto in support of the scientific activity of the Ma_MISS instrument by Marco Ferrari, Simone De Angelis, Alessandro Frigeri, Enrico Bruschini, Felipe Gómez, Maria Cristina De Sanctis

“…During the field campaign, we collected a large set of VIS-NIR (0.35–2.5 μm) measurements using the ASD FieldSpec4 portable spectrometer both on biosignature-bearing rocks and on alteration hydrated products (sulfates, clays, oxides, etc.). …”
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Integrity of the DNA and Cellular Ultrastructure of Cryptoendolithic Fungi in Space or Mars Conditions: A 1.5-Year Study at the International Space Station by Silvano Onofri, Laura Selbmann, Claudia Pacelli, Jean Pierre de Vera, Gerda Horneck, John E. Hallsworth, Laura Zucconi

“…We discuss the implications for using DNA, when properly shielded, as a biosignature of recently extinct or extant life.…”
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Identification of a Metabolism-Related Signature for the Prediction of Survival in Endometrial Cancer Patients by Yuan Fan, Xingchen Li, Li Tian, Jianliu Wang

“…The present study aims to identify a metabolism-related biosignature for EC and explore the molecular immune-related mechanisms underlying the tumorigenesis of EC.MethodsTranscriptomics and clinical data of EC were retrieved from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases. …”
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The volatilome – investigation of volatile organic metabolites (VOM) as potential tumor markers in patients with head and neck squamous cell carcinoma (HNSCC) by Philipp Opitz, Olf Herbarth

“…These volatile organic metabolites (VOM) represent a kind of biosignature that reflects the sum of all multifactorial influences, including genetics, environmental factors, nutritional and disease status. …”
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Spatial Metagenomics of Three Geothermal Sites in Pisciarelli Hot Spring Focusing on the Biochemical Resources of the Microbial Consortia by Roberta Iacono, Beatrice Cobucci-Ponzano, Federica De Lise, Nicola Curci, Luisa Maurelli, Marco Moracci, Andrea Strazzulli

“…This site is an excellent model for the study of biodiversity on Earth and biosignature identification, and for the study of the origin and limits of life.…”
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Venus Life Finder Habitability Mission: Motivation, Science Objectives, and Instrumentation by Seager, Sara, Petkowski, Janusz J., Carr, Christopher E., Saikia, Sarag J., Agrawal, Rachana, Buchanan, Weston P., Grinspoon, David H., Weber, Monika U., Klupar, Pete, Worden, Simon P., Iakubivskyi, Iaroslav, Pajusalu, Mihkel, Kaasik, Laila, on behalf of the Venus Life Finder Mission Team

“…We envision an instrument suite to measure not only the acidity and water content of the droplets (and their variability) but additionally to confirm the presence of metals and other non-volatile elements required for life’s metabolism, verify the existence of organic material, and search for biosignature gases as signs of life. We present an astrobiology-focused mission, science goals, and instruments that can be used on both a large atmospheric probe with a parachute lasting about one hour in the cloud layers (40 to 60 km) or a fixed-altitude balloon operating at about 52 km above the surface. …”
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