How to Search for Life in Martian Chemical Sediments and Their Fluid and Solid Inclusions Using Petrographic and Spectroscopic Methods by Kathleen C. Benison

“…Satellites, landers, and rovers have tested atmospheric gases, general sediment and rock compositions, and images of Mars surface in an effort to detect biosignatures left by any possible modern or ancient life. …”
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Optimising treatment decision rules through generated effect modifiers: a precision medicine tutorial by Eva Petkova, Hyung Park, Adam Ciarleglio, R. Todd Ogden, Thaddeus Tarpey

“…The methods detailed in this tutorial define composite variables from the patient measures that can be viewed as ‘biosignatures’ for differential treatment response, which we have termed ‘generated effect modifiers’. …”
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Sparse learning and stability selection for predicting MCI to AD conversion using baseline ADNI data by Ye Jieping, Farnum Michael, Yang Eric, Verbeeck Rudi, Lobanov Victor, Raghavan Nandini, Novak Gerald, DiBernardo Allitia, Narayan Vaibhav A

“…Identifying MCI individuals with high likelihood of conversion to dementia and the associated biosignatures has recently received increasing attention in AD research. …”
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Molecular preservation of 1.88 Ga Gunflint organic microfossils as a function of temperature and mineralogy by Julien Alleon, Sylvain Bernard, Corentin Le Guillou, Johanna Marin-Carbonne, Sylvain Pont, Olivier Beyssac, Kevin D. McKeegan, François Robert

“…Thermal diagenesis is generally seen as detrimental to the preservation of organic biosignatures. Using synchrotron-based XANES data, Alleon et al.find preservation of the molecular signatures of organic microfossils from the 1.88 Ga Gunflint cherts.…”
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Catalytic/Protective Properties of Martian Minerals and Implications for Possible Origin of Life on Mars by Teresa Fornaro, Andrew Steele, John Robert Brucato

“…Therefore, this contribution aims at reviewing the most important investigations carried out so far about the catalytic/protective properties of Martian minerals toward molecular biosignatures under Martian-like conditions. Overall, it turns out that the fate of molecular biosignatures on Mars depends on a delicate balance between multiple preservation and degradation mechanisms, often regulated by minerals, which may take place simultaneously. …”
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12.458 Molecular Biogeochemistry, Fall 2006 by Summons, Roger

“…This course covers all aspects of molecular biosignatures from their pathways of lipid biosynthesis, the distribution patterns of lipid biosynthetic pathways with regard to phylogeny and physiology, isotopic contents, occurrence in modern organisms and environments, diagenetic pathways, analytical techniques and the occurrence of molecular fossils through the geological record.…”
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Earliest signs of life on land preserved in ca. 3.5 Ga hot spring deposits by Tara Djokic, Martin J. Van Kranendonk, Kathleen A. Campbell, Malcolm R. Walter, Colin R. Ward

“…Here, the authors present evidence for ca. 3.5 Ga hot spring deposits from the Dresser Formation, Pilbara Craton, Australia, that host some of the earliest known life in the form of stromatolites and other microbial biosignatures.…”
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Viroids-First—A Model for Life on Earth, Mars and Exoplanets by Karin Moelling, Felix Broecker

“…The search for extraterrestrial life, recently fueled by the discovery of exoplanets, requires defined biosignatures. Current biomarkers include those of extremophilic organisms, typically archaea. …”
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A review of microbial‐environmental interactions recorded in Proterozoic carbonate‐hosted chert by Moore, Kelsey R, Gong, Jian, Williford, Kenneth, Konhauser, Kurt, Bosak, Tanja, DAYE, MIRNA

“…Early diagenetic chert preserves some of the most exceptional Proterozoic biosignatures in the form of microbial body fossils and mat textures. …”
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Multitechnique characterization of secondary minerals near HI-SEAS, Hawaii, as Martian subsurface analogues by Sebastian J. Mulder, Frank J. A. van Ruitenbeek, Bernard H. Foing, Mónica Sánchez-Román

“…The coralloid speleothem layers are likely related to wet and dry periods in which opal and calcite precipitates in cycles. Potential biosignatures seem to have been preserved in the form of porous stromatolite-like layers within the coralloid speleothems. …”
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The search for a signature of life on Mars: a biogeomorphological approach by Corenblit, D, Darrozes, J, Julien, F, Otto, T, Roussel, E, Steiger, J, Viles, H

“…Biogeomorphological characteristics, especially those involving microorganisms, are potentially important facets of biosignatures on Mars and are generating increasing interest in astrobiology. …”

An untargeted exometabolomics approach to characterize dissolved organic matter in groundwater of the Samail Ophiolite by Lauren M. Seyler, Lauren M. Seyler, Lauren M. Seyler, Emily A. Kraus, Emily A. Kraus, Craig McLean, John R. Spear, Alexis S. Templeton, Matthew O. Schrenk, Matthew O. Schrenk

“…Metabolomics techniques like the ones used in this study may be used to further our understanding of life in serpentinizing environments, and aid in the identification of biosignatures that can be used to search for life in serpentinizing systems on other worlds.…”
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Downregulation of miR-1 enhances tumorigenicity and invasiveness in oral squamous cell carcinomas by Chih-Yu Peng, Yi-Wen Liao, Ming-Yi Lu, Chuan-Hang Yu, Cheng-Chia Yu, Ming-Yung Chou

“…Cumulative evidence suggest that microRNAs (miRNAs) function as biosignatures of oral squamous cell carcinomas (OSCC). …”
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Applying Novel Techniques from Physical and Biological Sciences to Life Detection by Tony Z. Jia, Chaitanya Giri, Andrea Aldaba, Ilknur Bahcivan, Nipun Chandrasiri, Ilankuzhali Elavarasan, Kashish Gupta, Sakshi P. Khandare, Christos Liaconis, Arpita Saha, Orlando J. Solórzano, Paola Ines Tiranti, Aivaras Vilutis, Graham E. Lau

“…These techniques broadly fall under three categories: instrumentation for in situ measurements of biosignatures within the solar system, calculations or observational techniques for remote measurements of exoplanet biosignatures, and technosignatures. …”
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Raman and SEM analysis of a biocolonised hot spring travertine terrace in Svalbard, Norway by Jorge-Villar Susana E, Benning Liane G, Edwards Howell GM

“…No morphological biosignatures representing remnant microbial signals were detected by high-resolution imaging, although spectral analyses indicated the presence of organics. …”
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A New Definition of Exoplanet Habitability: Introducing the Photosynthetic Habitable Zone by C. Hall, P. C. Stancil, J. P. Terry, C. K. Ellison

“…It may be possible to detect biosignatures of photosynthesis in an exoplanet’s atmosphere. …”
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Exploring structure, microbiota, and metagenome functions of epigean and hypogean black deposits by microscopic, molecular and bioinformatic approaches by Beatrice Farda, Ilaria Vaccarelli, Claudia Ercole, Rihab Djebaili, Maddalena Del Gallo, Marika Pellegrini

“…Micrographs showed that samples presented microbial biosignatures and microanalyses highlighted Mn concretions and layers on Al-Si surfaces. …”
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The Abundance of Belatedly Habitable Planets and Ambiguities in Definitions of the Continuously Habitable Zone by Noah W. Tuchow, Jason T. Wright

“…Calculating the fraction of habitable zone planets in the CHZ as a function of stellar properties, we find that the quality of a star as a host for planets with long-term habitability and biosignatures depends strongly on the formulation of the CHZ used. …”
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Functional correlations of pathogenesis-driven gene expression signatures in tuberculosis. by Jeroen Maertzdorf, Martin Ota, Dirk Repsilber, Hans J Mollenkopf, January Weiner, Philip C Hill, Stefan H E Kaufmann

“…Tuberculosis remains a major health threat and its control depends on improved measures of prevention, diagnosis and treatment. Biosignatures can play a significant role in the development of novel intervention measures against TB and blood transcriptional profiling is increasingly exploited for their rational design. …”
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12.158 / 12.458 Molecular Biogeochemistry, Fall 2010 by Summons, Roger, Hallmann, Christian, Sepulveda, Julio

“…This course covers all aspects of molecular biosignatures, such as their pathways of lipid biosynthesis, the distribution patterns of lipid biosynthetic pathways with regard to phylogeny and physiology, isotopic contents, occurrence in modern organisms and environments, diagenetic pathways, analytical techniques and the occurrence of molecular fossils through the geological record. …”
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