A characteristic cerebellar biosignature for bipolar disorder, identified with fully automatic machine learning by Georgios V. Thomaidis, Konstantinos Papadimitriou, Sotirios Michos, Evangelos Chartampilas, Ioannis Tsamardinos

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Silica deposits on Mars with features resembling hot spring biosignatures at El Tatio in Chile by Steven W. Ruff, Jack D. Farmer

“…Hydrothermal deposits on Mars may provide the best opportunity to find Martian biosignatures. Ruff and Farmer report that silica structures created by biotic and abiotic process in hot springs at El Tatio, Chile resemble those found in Gusev crater, thus making it an ideal location for future missions.…”
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The corticolimbic structural covariance network as an early predictive biosignature for cognitive impairment in Parkinson's disease by Yueh-Sheng Chen, Hsiu-Ling Chen, Cheng-Hsien Lu, Chih-Ying Lee, Kun-Hsien Chou, Meng-Hsiang Chen, Chiun-Chieh Yu, Yun-Ru Lai, Pi-Ling Chiang, Wei-Che Lin

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Onboard Science Instrument Autonomy for the Detection of Microscopy Biosignatures on the Ocean Worlds Life Surveyor by Mark Wronkiewicz, Jake Lee, Lukas Mandrake, Jack Lightholder, Gary Doran, Steffen Mauceri, Taewoo Kim, Nathan Oborny, Thomas Schibler, Jay Nadeau, James K. Wallace, Eshaan Moorjani, Chris Lindensmith

Subjects: “…Biosignatures…”
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Accurate Blood-Based Diagnostic Biosignatures for Alzheimer’s Disease via Automated Machine Learning by Makrina Karaglani, Krystallia Gourlia, Ioannis Tsamardinos, Ekaterini Chatzaki

“…In the present study, we analyzed publicly available high-throughput low-sample -omics datasets from studies in AD blood, by the AutoML technology Just Add Data Bio (JADBIO), to construct accurate predictive models for use as diagnostic biosignatures. Considering data from AD patients and age–sex matched cognitively healthy individuals, we produced three best performing diagnostic biosignatures specific for the presence of AD: A. …”
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Trace Element Concentrations Associated with Mid-Paleozoic Microfossils as Biosignatures to Aid in the Search for Life by Andrew Gangidine, Malcolm R. Walter, Jeff R. Havig, Clive Jones, Daniel M. Sturmer, Andrew D. Czaja

Subjects: “…biosignatures…”
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A Spectral Comparison of Jarosites Using Techniques Relevant to the Robotic Exploration of Biosignatures on Mars by Liane Loiselle, Michael A. McCraig, M. Darby Dyar, Richard Léveillé, Sean R. Shieh, Gordon Southam

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Reflected Spectroscopy of Small Exoplanets. III. Probing the UV Band to Measure Biosignature Gases by Mario Damiano, Renyu Hu, Bertrand Mennesson

“…However, this O _2 –O _3 biosignature is not detectable in the visible wavelengths for most of the time after the emergence of oxygenic photosynthesis life (i.e., Proterozoic Earth). …”
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Planetary Science Meets Chemistry: Studying Potential Biosignature Gases in Terrestrial Exoplanet Atmospheres by Huang, Jingcheng

“…As more and more exoplanets are discovered, searching for biosignature gases is becoming one of the crucial ways to find extraterrestrial life. …”
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Organic Carbonyls Are Poor Biosignature Gases in Exoplanet Atmospheres but May Generate Significant CO by Zhan, Zhuchang, Huang, Jingcheng, Seager, Sara, Petkowski, Janusz J, Ranjan, Sukrit

“…<jats:title>Abstract</jats:title> <jats:p>The search for signs of life beyond Earth is a crucial driving motivation of exoplanet science, fueling new work on biosignature gases in habitable exoplanet atmospheres. …”
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Preservation of Martian Organic and Environmental Records: Final Report of the Mars Biosignature Working Group by Amend, Jan P., Bish, David, Buick, Roger, Cody, George D., Des Marias, David J., Dromart, Gilles, Eigenbrode, Jennifer L., Knoll, Andrew H., Sumner, Dawn Y., Summons, Roger E

“…It can also document other potential biosignature repositories such as hydrothermal environments. …”
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Urinary Volatomic Expression Pattern: Paving the Way for Identification of Potential Candidate Biosignatures for Lung Cancer by Khushman Taunk, Priscilla Porto-Figueira, Jorge A. M. Pereira, Ravindra Taware, Nattane Luíza da Costa, Rommel Barbosa, Srikanth Rapole, José S. Câmara

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The Cell and the Sum of Its Parts: Patterns of Complexity in Biosignatures as Revealed by Deep UV Raman Spectroscopy by Haley M. Sapers, Haley M. Sapers, Haley M. Sapers, Joseph Razzell Hollis, Rohit Bhartia, Luther W. Beegle, Victoria J. Orphan, Jan P. Amend, Jan P. Amend

Subjects: “…biosignatures…”
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Fossil Biomarkers and Biosignatures Preserved in Coprolites Reveal Carnivorous Diets in the Carboniferous Mazon Creek Ecosystem by Madison Tripp, Jasmina Wiemann, Jochen Brocks, Paul Mayer, Lorenz Schwark, Kliti Grice

“…Molecular and biosignature preservation is facilitated by rapid sedimentary encapsulation of the coprolites within days to months after egestion.…”
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A Plasma 5-Marker Host Biosignature Identifies Tuberculosis in High and Low Endemic Countries by Bih H. Chendi, Bih H. Chendi, Candice I. Snyders, Kristian Tonby, Kristian Tonby, Synne Jenum, Martin Kidd, Gerhard Walzl, Novel N. Chegou, Anne M. Dyrhol-Riise, Anne M. Dyrhol-Riise

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Clinical Insights into Mitochondrial Neurodevelopmental and Neurodegenerative Disorders: Their Biosignatures from Mass Spectrometry-Based Metabolomics by Haorong Li, Martine Uittenbogaard, Ling Hao, Anne Chiaramello

“…We conclude by exploring the MS-based metabolomic functional insights into their biosignatures to improve diagnostic platforms, stratify patients, and design novel targeted therapeutic strategies.…”
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The ORIGIN Space Instrument for Detecting Biosignatures and Habitability Indicators on a Venus Life Finder Mission by Niels F. W. Ligterink, Kristina A. Kipfer, Salome Gruchola, Nikita J. Boeren, Peter Keresztes Schmidt, Coenraad P. de Koning, Marek Tulej, Peter Wurz, Andreas Riedo

“…A Venus Life Finder mission will require dedicated and specialized instruments to hunt for biosignatures and habitability indicators. In this contribution, we present the ORIGIN space instrument, a laser desorption/laser ablation ionization mass spectrometer. …”
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Controls on Reactive Oxygen Species Cycles in Yellowstone Hot Springs: Implications for Biosignature Preservation on Mars by Nancy W. Hinman, Megan A. Mave, Leanne C. Powers, Philippe Schmitt-Kopplin, Philippe Schmitt-Kopplin, Nathalie A. Cabrol, Michael Gonsior

“…Hot spring deposits are compelling targets for exploration because of their high habitability and potential to retain morphological and chemical biosignatures. As a result in this study, we aim to better understand the potential for biosignature preservation in Fe-bearing hydrothermal systems. …”
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Deciphering the Methylation Landscape in Breast Cancer: Diagnostic and Prognostic Biosignatures through Automated Machine Learning by Maria Panagopoulou, Makrina Karaglani, Vangelis G. Manolopoulos, Ioannis Iliopoulos, Ioannis Tsamardinos, Ekaterini Chatzaki

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Quantitative proteomics and phosphoproteomics of urinary extracellular vesicles define putative diagnostic biosignatures for Parkinson’s disease by Marco Hadisurya, Li Li, Kananart Kuwaranancharoen, Xiaofeng Wu, Zheng-Chi Lee, Roy N. Alcalay, Shalini Padmanabhan, W. Andy Tao, Anton Iliuk

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