Total Body Irradiation Mitigates Inflammation and Extends the Therapeutic Time Window for Anti-Ricin Antibody Treatment against Pulmonary Ricinosis in Mice by Yoav Gal, Anita Sapoznikov, Reut Falach, Sharon Ehrlich, Moshe Aftalion, Chanoch Kronman, Tamar Sabo

“…Ricin, a highly toxic plant-derived toxin, is considered a potential weapon in biowarfare and bioterrorism due to its pronounced toxicity, high availability, and ease of preparation. …”
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The current and future landscape of smallpox vaccines by J. Michael Lane

“…The potential use of smallpox as a weapon for bioterrorism has created a need for more and better smallpox vaccines. …”
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Genomic population structure associated with repeated escape of Salmonella enterica ATCC14028s from the laboratory into nature. by Mark Achtman, Frederik Van den Broeck, Kerry K Cooper, Philippe Lemey, Craig T Parker, Zhemin Zhou, ATCC14028s Study Group

“…ATCC14028s has been implicated in multiple cross-contaminations in the laboratory, and has also caused multiple laboratory infections and one known attempt at bioterrorism. According to hierarchical clustering of 3002 core gene sequences, ATCC14028s belongs to HierCC cluster HC20_373 in which most internal branch lengths are only one to three SNPs long. …”
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Lovastatin protects against experimental plague in mice. by Saravanan Ayyadurai, Hubert Lepidi, Claude Nappez, Didier Raoult, Michel Drancourt

“…BACKGROUND: Plague is an ectoparasite-borne deadly infection caused by Yersinia pestis, a bacterium classified among the group A bioterrorism agents. Thousands of deaths are reported every year in some African countries. …”
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Francisella tularensis: No Evidence for Transovarial Transmission in the Tularemia Tick Vectors Dermacentor reticulatus and Ixodes ricinus. by Marco Genchi, Paola Prati, Nadia Vicari, Andrea Manfredini, Luciano Sacchi, Emanuela Clementi, Claudio Bandi, Sara Epis, Massimo Fabbi

“…Due to easy dissemination, multiple routes of infection, high environmental contamination and morbidity and mortality rates, Francisella is considered a potential bioterrorism threat and classified as a category A select agent by the CDC. …”
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Gastrointestinal and cutaneous anthrax: Case series by Vildan Ozer, Mucahit Gunaydin, Sinan Pasli, Firdevs Aksoy, Abdulkadir Gunduz

“…Conclusion: We presented this article, to update our information about gastrointestinal anthrax and other anthrax types which are become a current issue again especially due to bioterrorism and also to keep it in mind in the differential diagnosis although it is rarely seen in our stock raising areas.…”
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Bacteriological analysis of street-vended fruit juices available in Rishikesh, Uttarakhand by Yatharth Malik, Balram Ji Omar, Arpana Singh

“…Conclusion: The plethora of microbial contamination of street-vended fruit juices is a lucrative dimension for research in fruit juice microbiology to improve general public health, reduce disease mortality and morbidity, reduce economic losses, and to protect the general public from the risk of bioterrorism by stringent surveillance in background of limited employment opportunities and constrained livelihoods of the vendors.…”
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A software tool for creating simulated outbreaks to benchmark surveillance systems by Olson Karen L, Iancu Karin, Cassa Christopher A, Mandl Kenneth D

“…<p>Abstract</p> <p>Background</p> <p>Evaluating surveillance systems for the early detection of bioterrorism is particularly challenging when systems are designed to detect events for which there are few or no historical examples. …”
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Design of a chitosan-based nano vaccine against epsilon toxin of Clostridium perfringens type D and evaluation of its immunogenicity in BALB/c mice by Farnaz Poorhassan, Fahimeh Nemati, Parvaneh Saffarian, Seyed Ali Mirhosseini, Mohammad Javad Motamedi

“…This bacterium can produce 5 main toxins (alpha, beta, epsilon, iota, and a type of enterotoxin) among which the epsilon toxin (ETX) is used for bioterrorism. This toxin can be prevented by immunization with specific immunogenic vaccines. …”
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Public health response systems in-action: learning from local health departments' experiences with acute and emergency incidents. by Jennifer C Hunter, Jane E Yang, Adam W Crawley, Laura Biesiadecki, Tomás J Aragón

“…In this study, we interviewed representatives from more than 120 local health departments regarding their recent experiences with real-world acute public health incidents, such as infectious disease outbreaks, severe weather events, chemical spills, and bioterrorism threats. We collected highly structured data on key aspects of the incident and the public health response, particularly focusing on the public health activities initiated and community partners engaged in the response efforts. …”
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Levofloxacin cures experimental pneumonic plague in African green monkeys. by Robert Colby Layton, William Mega, Jacob D McDonald, Trevor L Brasel, Edward B Barr, Andrew P Gigliotti, Frederick Koster

“…Levofloxacin may also be considered for primary presumptive-use, multi-agent antibiotic in bioterrorism events prior to identification of the pathogen.…”
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Virus detection and identification using random multiplex (RT)-PCR with 3'-locked random primers by Eaton John W, Telang Sucheta, Sims Jonathan, Clem Amy L, Chesney Jason

“…Unfortunately, high mutation rates may lead to extensive changes in viral nucleic acid sequences making dedicated PCR primer use problematic. Furthermore, in bioterrorism, viral consensus sequences can be genetically modified as a countermeasure to RT-PCR and DNA chip detection. …”
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Vaccination greatly reduces disease, disability, death and inequity worldwide by FE Andre, R Booy, HL Bock, J Clemens, SK Datta, TJ John, BW Lee, S Lolekha, H Peltola, TA Ruff, M Santosham, HJ Schmitt

“…Vaccines are considered indispensable against bioterrorism. They can combat resistance to antibiotics in some pathogens. …”
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The use of resazurin as a novel antimicrobial agent against Francisella tularensis by Deanna Marie Schmitt, Dawn M O'Dee, Brianna N Cowan, James W.-M. Birch, Leanne K Mazzella, Gerard J Nau, Gerard J Nau, Joseph eHorzempa

“…The highly infectious and deadly pathogen, Francisella tularensis, is classified by the CDC as a Category A bioterrorism agent. Inhalation of a single bacterium results in an acute pneumonia with a 30-60% mortality rate without treatment. …”
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Detection of Non-PCR Amplified &lt;em&gt;S. enteritidis&lt;/em&gt; Genomic DNA from Food Matrices Using a Gold-Nanoparticle DNA Biosensor: A Proof-of-Concept Study by Evangelyn C. Alocilja, Michael C. Huarng, Sylvia A. Vetrone

“…Bacterial pathogens pose an increasing food safety and bioterrorism concern. Current DNA detection methods utilizing sensitive nanotechnology and biosensors have shown excellent detection, but require expensive and time-consuming polymerase chain reaction (PCR) to amplify DNA targets; thus, a faster, more economical method is still essential. …”
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Risk Assessment and Management in Pervasive Computing : Operational, Legal, Ethical, and Financial Perspectives / by Godara, Varuna, editor 501171, IGI Global (Online service) 631983

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Lactonase-mediated inhibition of quorum sensing largely alters phenotypes, proteome, and antimicrobial activities in Burkholderia thailandensis E264 by Mélanie Gonzales, Mélanie Gonzales, Laure Plener, Jean Armengaud, Nicholas Armstrong, Éric Chabrière, David Daudé

“…IntroductionBurkholderia thailandensis is a study model for Burkholderia pseudomallei, a highly virulent pathogen, known to be the causative agent of melioidosis and a potential bioterrorism agent. These two bacteria use an (acyl-homoserine lactone) AHL-mediated quorum sensing (QS) system to regulate different behaviors including biofilm formation, secondary metabolite productions, and motility.MethodsUsing an enzyme-based quorum quenching (QQ) strategy, with the lactonase SsoPox having the best activity on B. thailandensis AHLs, we evaluated the importance of QS in B. thailandensis by combining proteomic and phenotypic analyses.ResultsWe demonstrated that QS disruption largely affects overall bacterial behavior including motility, proteolytic activity, and antimicrobial molecule production. …”
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Cellular entry of ebola virus involves uptake by a macropinocytosis-like mechanism and subsequent trafficking through early and late endosomes. by Mohammad F Saeed, Andrey A Kolokoltsov, Thomas Albrecht, Robert A Davey

“…Zaire ebolavirus (ZEBOV), a highly pathogenic zoonotic virus, poses serious public health, ecological and potential bioterrorism threats. Currently no specific therapy or vaccine is available. …”
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Multisectoral prioritization of zoonotic diseases in Uganda, 2017: A One Health perspective. by Musa Sekamatte, Vikram Krishnasamy, Lilian Bulage, Christine Kihembo, Noelina Nantima, Fred Monje, Deo Ndumu, Juliet Sentumbwe, Betty Mbolanyi, Robert Aruho, Winyi Kaboyo, David Mutonga, Colin Basler, Sarah Paige, Casey Barton Behravesh

“…Criteria selected to prioritize zoonotic diseases were (1) severity of disease in humans in Uganda, (2) availability of effective control strategies, (3) potential to cause an epidemic or pandemic in humans or animals, (4) social and economic impacts, and (5) bioterrorism potential. Seven zoonotic diseases were identified as priorities for Uganda: anthrax, zoonotic influenza viruses, viral hemorrhagic fevers, brucellosis, African trypanosomiasis, plague, and rabies. …”
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Phylogenetic inference of Coxiella burnetii by 16S rRNA gene sequencing. by Heather P McLaughlin, Blake Cherney, Janetta R Hakovirta, Rachael A Priestley, Andrew Conley, Andrew Carter, David Hodge, Segaran P Pillai, Linda M Weigel, Gilbert J Kersh, David Sue

“…It is ubiquitous in the environment and due to its wide host range, long-range dispersal potential and classification as a bioterrorism agent, this microorganism is considered an HHS Select Agent. …”
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