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501
Determinants of emergency response willingness in the local public health workforce by jurisdictional and scenario patterns: a cross-sectional survey
Published 2012-03-01“…Across the eight clusters, the percentage of workers indicating they would be unwilling to respond regardless of severity ranged from 14-28% for a weather event; 9-27% for pandemic influenza; 30-56% for a radiological 'dirty' bomb event; and 22-48% for an inhalational anthrax bioterrorism event. Efficacy was consistently identified as an important independent predictor of WTR.…”
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502
An automated, broad-based, near real-time public health surveillance system using presentations to hospital Emergency Departments in New South Wales, Australia
Published 2005-12-01“…<p>Abstract</p> <p>Background</p> <p>In a climate of concern over bioterrorism threats and emergent diseases, public health authorities are trialling more timely surveillance systems. …”
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503
A historical and proteomic analysis of botulinum neurotoxin type/G
Published 2011-10-01“…There are seven known serotypes of BoNTs (/A through/G), all of which are potent toxins classified as category A bioterrorism agents. BoNT/G is the least studied of the seven serotypes. …”
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504
Working correlates of protection predict SchuS4-derived-vaccine candidates with improved efficacy against an intracellular bacterium, Francisella tularensis
Published 2022-08-01“…Abstract Francisella tularensis, the causative agent of tularemia, is classified as Tier 1 Select Agent with bioterrorism potential. The efficacy of the only available vaccine, LVS, is uncertain and it is not licensed in the U.S. …”
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505
Crystal Structure of the Receptor-Binding Domain of Botulinum Neurotoxin Type HA, Also Known as Type FA or H
Published 2017-03-01“…They pose a potential bioterrorism threat because they cause botulism, a flaccid muscular paralysis-associated disease that requires immediate antitoxin treatment and intensive care over a long period of time. …”
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506
Structural and biophysical properties of FopA, a major outer membrane protein of Francisella tularensis
Published 2022-01-01“…Francisella tularensis is an extremely infectious pathogen and a category A bioterrorism agent. It causes the highly contagious zoonosis, Tularemia. …”
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507
Bacillus anthracis infections – new possibilities of treatment
Published 2015-05-01“…[i]Bacillus anthracis[/i] is one of biological agents which may be used in bioterrorism attacks. The aim of this study a review of the new treatment possibilities of anthrax, with particular emphasis on the treatment of pulmonary anthrax. …”
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508
Gene expression profiling of human alveolar macrophages infected by <it>B. anthracis </it>spores demonstrates TNF-α and NF-κb are key components of the innate immune response to th...
Published 2009-09-01“…<p>Abstract</p> <p>Background</p> <p><it>Bacillus anthracis</it>, the etiologic agent of anthrax, has recently been used as an agent of bioterrorism. The innate immune system initially appears to contain the pathogen at the site of entry. …”
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509
A Survey of Location-Allocation of Points of Dispensing During Public Health Emergencies
Published 2022-03-01“…Public health emergencies such as disease outbreaks and bioterrorism attacks require immediate response to ensure the safety and well-being of the affected community and prevent the further spread of infection. …”
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510
Identification, Functional Characterization and Regulon Prediction of a Novel Two Component System Comprising BAS0540-BAS0541 of Bacillus anthracis.
Published 2016-01-01“…Two component systems (TCSs) can be envisaged as complex molecular devices that help the bacteria to sense its environment and respond aptly. 41 TCSs are predicted in Bacillus anthracis, a potential bioterrorism agent, of which only four have been studied so far. …”
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511
Construction of a bivalent vaccine against anthrax and smallpox using the attenuated vaccinia virus KVAC103
Published 2021-03-01“…Abstract Background Anthrax and smallpox are high-risk infectious diseases, and considered as potential agents for bioterrorism. To develop an effective countermeasure for these diseases, we constructed a bivalent vaccine against both anthrax and smallpox by integrating a gene encoding protective antigen (PA) of Bacillus anthracis to the genome of the attenuated vaccinia virus strain, KVAC103. …”
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512
Rapid Phenotypic Antibiotic Susceptibility Profiling of Clinical <i>Escherichia coli</i> and <i>Klebsiella pneumoniae</i> Blood Cultures
Published 2024-02-01“…We have previously shown that our novel rapid AST method, MAPt (Micro-Agar-PCR-test), accurately identifies susceptibility profiles for spiked bioterrorism agents like <i>Bacillus anthracis</i>, <i>Yersinia pestis</i> and <i>Francisella tularensis</i> directly from whole-blood and blood culture samples, even at low bacterial levels (500 CFU/mL). …”
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513
Structural and biophysical properties of FopA, a major outer membrane protein of Francisella tularensis.
Published 2022-01-01“…Francisella tularensis is an extremely infectious pathogen and a category A bioterrorism agent. It causes the highly contagious zoonosis, Tularemia. …”
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514
Optimization of Sample Preparation for the Identification and Quantification of Saxitoxin in Proficiency Test Mussel Sample using Liquid Chromatography-Tandem Mass Spectrometry
Published 2015-11-01“…The developed method was applied to the analysis of the homogenized mussel samples in the proficiency test (PT) within the EQuATox project (Establishment of Quality Assurance for the Detection of Biological Toxins of Potential Bioterrorism Risk). Ten laboratories from eight countries participated in the STX PT. …”
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515
COVID-19 vaccination in the national security system of the Russian Federation: coordination of private and public interests
Published 2022-12-01“…The development of this institution requires a rational legal support, considering not only current epidemic process, but also potential threats of bioterrorism and the development of biological weapons. …”
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516
Humoral immunity, vaccination period and demographic characteristics of first immunized smallpox vaccine recipients
Published 2021-02-01“…The recurrence of research interest in smallpox vaccine is due to the research of using the virus as a weapon of bioterrorism and the increased frequency of orthopoxvirus infections whereas the population immunity decline. …”
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517
Retrospective Analysis of Official Data on Anthrax in Europe with a Special Reference to Ukraine
Published 2023-05-01“…Furthermore, <i>B. anthracis</i> is considered one of the most important biological agents of bioterrorism that could also be potentially misused in biological weapons. …”
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518
A software tool for creating simulated outbreaks to benchmark surveillance systems
Published 2010“…Background: Evaluating surveillance systems for the early detection of bioterrorism is particularly challenging when systems are designed to detect events for which there are few or no historical examples. …”
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519
Botulinum Neurotoxin Detection Methods for Public Health Response and Surveillance
Published 2018-06-01“…Botulism outbreak due to consumption of food contaminated with botulinum neurotoxins (BoNTs) is a public health emergency. The threat of bioterrorism through deliberate distribution in food sources and/or aerosolization of BoNTs raises global public health and security concerns due to the potential for high mortality and morbidity. …”
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520
Functional epitopes and neutralizing antibodies of vaccinia virus
Published 2023-10-01“…In recent years the potential threat of bioterrorism using smallpox has led to resumed research on the treatment and prevention of smallpox. …”
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