The influence of psychoeducation on regulating biological rhythm in a sample of patients with bipolar II disorder: a randomized clinical trial by Faria AD, de Mattos Souza LD, de Azevedo Cardoso T, Pinheiro KAT, Pinheiro RT, da Silva RA, Jansen K

“…Augusto Duarte Faria,1 Luciano Dias de Mattos Souza,2 Taiane de Azevedo Cardoso,2 Karen Amaral Tavares Pinheiro,2 Ricardo Tavares Pinheiro,2 Ricardo Azevedo da Silva,2 Karen Jansen21Department of Clinical and Health Psychology, Universidade Federal do Rio Grande – FURG, Rio Grande, RS, Brazil; 2Health and Behavior Postgraduate Program, Universidade Católica de Pelotas – UCPEL, Pelotas, RS, BrazilIntroduction: Changes in biological rhythm are among the various characteristics of bipolar disorder, and have long been associated with the functional impairment of the disease. …”
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Antipsychotic prescribing for vulnerable populations: a clinical audit at an acute Australian mental health unit at two-time points by Sara S McMillan, Sara Jacobs, Louise Wilson, Theo Theodoros, Gail Robinson, Claire Anderson, Gabor Mihala, Amanda J Wheeler

“…Abstract Background Antipsychotics are recognised as a critical intervention for schizophrenia and bipolar disorder. Guidelines globally endorse the routine practice of antipsychotic monotherapy, at the minimum effective dose. …”
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Rapid methods including network meta-analysis to produce evidence in clinical decision support: a decision analysis by Øystein Eiring, Kjetil Gundro Brurberg, Kari Nytrøen, Magne Nylenna

“…Methods Long-term treatment in bipolar disorder was our testing field. We developed two new methods: an empirically based, rapid network meta-analysis (NMA) and an expert NMA, and conducted a patient survey. …”
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Multivariate Bayesian Arm-Based Network Meta-Analysis of Pharmacological Interventions for the Treatment of Acute Bipolar Mania in Adults by Palash Kumar Malo, Binukumar Bhaskarapillai, Muralidharan Kesavan

“…Conclusions: The findings favoring olanzapine, paliperidone, and quetiapine possess an excellent concordance with the one adopted in clinical practice, and the Canadian Network for Mood and Anxiety Treatments and Royal Australian and New Zealand College of Psychiatrists guidelines recommend these as first-line drugs for treating bipolar disorder.…”
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Attention-Related Brain Activation Is Altered in Older Adults With White Matter Hyperintensities Using Multi-Echo fMRI by Sarah Atwi, Sarah Atwi, Arron W. S. Metcalfe, Arron W. S. Metcalfe, Andrew D. Robertson, Jeremy Rezmovitz, Nicole D. Anderson, Nicole D. Anderson, Bradley J. MacIntosh, Bradley J. MacIntosh

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GABRB2 Haplotype Association with Heroin Dependence in Chinese Population. by Yung Su Kim, Mei Yang, Wai-Kin Mat, Shui-Ying Tsang, Zhonghua Su, Xianfei Jiang, Siu-Kin Ng, Siyu Liu, Taobo Hu, Frank Pun, Yanhui Liao, Jinsong Tang, Xiaogang Chen, Wei Hao, Hong Xue

“…Two additional SNPs, rs10051667 (S31) and rs967771 (S32), previously associated with alcohol dependence and bipolar disorder respectively, were also analyzed. The six SNPs were genotyped by direct sequencing of PCR amplicons of target regions for 564 heroin dependent individuals and 498 controls of Han Chinese origin. …”
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The composition of peripheral immunocompetent cell subpopulations and cytokine content in the brain structures of mutant Disc1-Q31L mice by M. M. Gevorgyan, S. Ya. Zhanaeva, E. L. Alperina, T. V. Lipina, G. V. Idova

“…The DISC1 (disrupted in sсhizophrenia 1) gene is associated with brain dysfunctions, which are involved in a variety of mental disorders, such as schizophrenia, depression and bipolar disorder. This is the first study to examine the immune parameters in Disc1-Q31L mice with a point mutation in the second exon of the DISC1 gene compared to mice of the C57BL/6NCrl strain (WT, wild type). …”
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Neurodevelopment regulators miR-137 and miR-34 family as biomarkers for early and adult onset schizophrenia by Bao-Yu Chen, Jin-Jia Lin, Ming-Kun Lu, Hung-Pin Tan, Fong-Lin Jang, Sheng-Hsiang Lin

“…This study included 215 schizophrenia patients (104 EOS and 111 AOS), 72 unaffected first-degree relatives, 31 patients with bipolar disorder, and 100 healthy controls. Differential expression analysis revealed that miR-137, miR-34b, and miR-34c were significantly up-regulated in patients with schizophrenia and their unaffected first-degree relatives compared to healthy controls. …”
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Community perceptions and attitudes toward serious mental illness in Cambodia by Bunna Phoeun, Sareth Khann, Chanthorn Leang, Thea Soung, Kevin Conroy, Amanda J. Nguyen

“…Background: Worldwide, approximately 64 million people are living with serious mental illnesses (SMI), such as schizophrenia and bipolar disorder. Because community perceptions and attitudes can impact help-seeking and the course of illness, understanding and incorporating these perspectives, and addressing misconceptions and harmful attitudes, is a critical component of comprehensive mental health support. …”
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357 Inflammatory Cytokines and Neurocognitive Functioning in Bipolar Patients across Mood Episodes by Sandra I. Ralat, Karen Martinez, Rosa J. Rodriguez, Yamil Gerena

“…OBJECTIVES/GOALS: Accumulating evidence supports the involvement of immune and inflammatory pathways in Bipolar Disorder (BD) pathophysiology. This pilot study aims to determine if altered peripheral IL-2, TNF-a, IL-4, IL-6, IL-10, IFN-y, IL-17A levels are associated with BD across mood episodes (euthymic, manic, depressive), and worsen neurocognitive function. …”
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Identifying drug targets for neurological and psychiatric disease via genetics and the brain transcriptome. by Denis A Baird, Jimmy Z Liu, Jie Zheng, Solveig K Sieberts, Thanneer Perumal, Benjamin Elsworth, Tom G Richardson, Chia-Yen Chen, Minerva M Carrasquillo, Mariet Allen, Joseph S Reddy, Philip L De Jager, Nilufer Ertekin-Taner, Lara M Mangravite, Ben Logsdon, Karol Estrada, Philip C Haycock, Gibran Hemani, Heiko Runz, George Davey Smith, Tom R Gaunt, AMP-AD eQTL working group

“…We causally linked the expression of 23 genes with schizophrenia and a single gene each with anorexia, bipolar disorder and major depressive disorder within the psychiatric diseases and 9 genes with Alzheimer's disease, 6 genes with Parkinson's disease, 4 genes with multiple sclerosis and two genes with amyotrophic lateral sclerosis within the neurological diseases we tested. …”
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Association of Chronic Obstructive Pulmonary Disease with Risk of Psychiatric Disorders: A Two-Sample Mendelian Randomization Study by Zhang Q, Zhang H, Xu Q

“…Although the past few years have witnessed significant scientific progress, the potential relationship between COPD and mental illness remains a subject of debate.Materials and Methods: We retrieved COPD data from the genome-wide association studies (GWAS) directory and data on mental illnesses, including Alzheimer’s disease, schizophrenia, panic disorder, attention deficit hyperactivity disorder (ADHD), bipolar disorder, major depressive disorder, multiple disabilities, obsessive-compulsive disorder, post-traumatic stress disorder, and schizophrenia, from the Psychiatric Genomics Consortium. …”
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Aripiprazole Attenuates Cognitive Impairments Induced by Lipopolysaccharide in Rats through the Regulation of Neuronal Inflammation, Oxidative Stress, and Apoptosis by Vasudevan Mani, Bander Shehail Alshammeri

“…<i>Background and Objectives</i>: Aripiprazole (APZ), an atypical antipsychotic, is mainly prescribed for conditions such as schizophrenia and bipolar disorder, while ongoing research indicates promising neuroprotective qualities. …”
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Evaluation of Cerebral Cortex Function in Clients with Bipolar Mood Disorder I (BMD I) Compared With BMD II Using QEEG Analysis by Ali Khaleghi, Ali Sheikhani, MohammadReza Mohammadi, Ali Moti-Nasrabadi

“…Methods: Thirty- eight adolescents (18 patients with bipolar disorder I and 20 with BMD II) participated in this study. …”
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Psychiatric Symptoms & Misdiagnosis Of Frontotemporal Dementia: A Case Report by G. Özmen, D. Göverti

“…She was admitted to the psychiatry hospital a year ago and discharged with a diagnosis of bipolar disorder. Brain MRI showed atrophy of frontal and anterior temporal structures bilaterally. …”
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Case Report: Long-Acting Oral Cariprazine by Emanuela Dyrmishi, Marco De Pieri, Marco De Pieri, Marco Ferrari, Rafael Traber, Matteo Preve, Luca De Peri, Emilio Bolla

“…IntroductionCariprazine is a third-generation antipsychotic, approved for the treatment of schizophrenia and bipolar disorder and used off-label for schizoaffective disorder and treatment-resistant depression. …”
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Physical injuries as triggers for self-harm: a within-individual study of nearly 250 000 injured people with a major psychiatric disorder by Pekka Martikainen, Keith Hawton, Henrik Larsson, Paul Lichtenstein, Seena Fazel, Joonas Pitkänen, Amir Sariaslan

“…Background Although there is robust evidence for several factors which may precipitate self-harm, the contributions of different physical injuries are largely unknown.Objective To examine whether specific physical injuries are associated with risks of self-harm in people with psychiatric disorders.Methods By using population and secondary care registers, we identified all people born in Finland (1955–2000) and Sweden (1948–1993) with schizophrenia-spectrum disorder (n=136 182), bipolar disorder (n=68 437) or depression (n=461 071). …”
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Dying young: Excess morbidity and mortality in individuals with severe mental illness and what we should be doing about it by Darya Kurowecki, Justin Godbout

“…The most common disorders that fall under this term include schizophrenia and bipolar disorder [1]. Over a decade of research into the morbidity and mortality of individuals with SMI has consistently revealed mortality rates two to three times higher and a life expectancy of 25-30 years shorter compared to the general population [1-4]. …”
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Circadian polymorphisms associated with affective disorders by Shekhtman Tatyana, Joo EJ, Nievergelt Caroline M, Kripke Daniel F, Kelsoe John R

“…</p> <p>Results</p> <p>In <it>NR1D1</it>, rs2314339 was associated with bipolar disorder (P = 0.0005). Among the unrelated bipolar participants, 3 SNPs in <it>PER3 </it>and <it>CSNK1E </it>were associated with the BALM score. …”
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Brain structural abnormalities in six major psychiatric disorders: shared variation and network perspectives [version 2; peer review: 1 approved, 2 approved with reservations] by Patricia Pelufo Silveira, Márcio Bonesso Alves, Euclides José de Mendonça Filho

“…The unidimensional solution indicated that brain alterations in autism spectrum disorder (ASD) had a significant negative component loading, suggesting that brain abnormalities found in ASD covaried with major depressive disorder (MDD), bipolar disorder (BD), schizophrenia (SCZ), and obsessive-compulsive disorder (OCD), a finding not demonstrated by the original work. …”
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