Characteristics Associated with Depression Severity in 270 Juveniles in a Major Depressive Episode by Giulia Serra, Maria Elena Iannoni, Monia Trasolini, Gino Maglio, Camilla Frattini, Maria Pia Casini, Ross J. Baldessarini, Stefano Vicari

“…<b>Results</b>: Depression severity was greater among females than males (55.0 vs. 47.2), with the diagnosis of a major depressive disorder (MDD) vs. bipolar disorder (BD; 53.8 vs. 49.3), and tended to increase with age (slope = 1.14). …”
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Diagnostic Task Specific Activations in Functional MRI and Aberrant Connectivity of Insula with Middle Frontal Gyrus Can Inform the Differential Diagnosis of Psychosis by Drozdstoy Stoyanov, Katrin Aryutova, Sevdalina Kandilarova, Rositsa Paunova, Zlatoslav Arabadzhiev, Anna Todeva-Radneva, Stefan Kostianev, Stefan Borgwardt

“…We hypothesized that areas demonstrating differential activation in two groups of patients (the first group exhibiting paranoid delusions in the context of paranoid schizophrenia—SCH—and second group with a depressive episode in the context of major depressive disorder or bipolar disorder—DEP) will have distinct connectivity patterns and structural differences. …”
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Comparison of Emotional Dysregulation Features in Cyclothymia and Adult ADHD by Giulio Emilio Brancati, Margherita Barbuti, Elisa Schiavi, Paola Colombini, Martina Moriconi, Alessandro Pallucchini, Marco Maiello, Giulia Menculini, Giulio Perugi

“…This group also showed significantly higher affective instability with respect to ADHD patients without cyclothymia and was less frequently diagnosed with bipolar disorder type II than patients from both the other groups. …”
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First-admissions in Psychiatry: a cluster analysis of a sample of inpatients from 2019 to 2021 by E. La Spina, M. Mastrangelo, B. Montalbani, I. Mancinelli, A. Del Casale, A. Comparelli, M. Pompili

“…They differ in the psychiatric diagnosis represented: respectively, Schizophrenia Spectrum Disorder and Bipolar Disorder with low suicidal risk, MDD, and Personality Disorders with a high suicidal risk. 39% of patients in cluster 1 were involuntarily admitted. …”
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Comparative evaluation of psychopharmacotherapy of atypical depression in bipolar and recurrent affective disorder, psychogenic depression by M. S. Verbitskaya, N. A. Tyuvina, Yu. G. Tyulpin, G. L. Krenkel

“…The proportion of responders among those who received AD for bipolar disorder (75% or more) was significantly higher than among those who did not receive it (˂50%). …”
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Humanistic and economic burden associated with depression in the United States: a cross-sectional survey analysis by Saundra Jain, Shaloo Gupta, Vicky W. Li, Ellison Suthoff, Alix Arnaud

“…Respondents not meeting eligibility criteria were excluded (e.g., those self-reporting bipolar disorder or experiencing depression in past 12 months but no depression diagnosis). …”
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The Study of the Prevalence of Psychiatric Disorders among Patients Referred to Farabi Hospital in Kermanshah, 2015-16 by O Davarinejad, A Karami, A Ahmadi, V Farnia, F Radmehr

“…The results showed that schizophrenia had the highest prevalence (25.8%) and delirium (1.5%) and dementia (1.8%) respectively. Also bipolar disorder was 19.3% and depression 11.3% were other common disorders. …”
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Association between Diffusion Tensor Imaging, inflammation and immunological alterations in unipolar and bipolar depression: a review by R. Aronica, P. Enrico, P. Brambilla, G. Delvecchio

“… Introduction Major Depressive Disorder (MDD) and Bipolar Disorder Depression (BDD) are common psychiatric illnesses characterized by structural and functional brain alterations and signs of neuroinflammation. …”
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Clinical feasibility of cognitive behavioural therapy for insomnia in a real-world mixed sample at a specialized psychiatric outpatient clinic by Maria Cassel, Kerstin Blom, Jannis Gatzacis, Peter Renblad, Viktor Kaldo, Susanna Jernelöv

“…In this pilot study, we aimed to determine the clinical feasibility of a group-based CBT-I intervention in an outpatient clinical setting for patients with depression, bipolar disorder, anxiety disorders and PTSD. We also aimed to investigate if symptoms of insomnia, depression and anxiety changed after CBT-I. …”
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Characterizing mood disorders in the AFFECT study: a large, longitudinal, and phenotypically rich genetic cohort in the US by Maria Dalby, Morana Vitezic, Niels Plath, Lene Hammer-Helmich, Yunxuan Jiang, Chao Tian, Devika Dhamija, Catherine H. Wilson, David Hinds, 23andMe Research Team, Patrick F. Sullivan, Joshua W. Buckholtz, Jordan W. Smoller

“…Abstract There has recently been marked progress in identifying genetic risk factors for major depression (MD) and bipolar disorder (BD); however, few systematic efforts have been made to elucidate heterogeneity that exists within and across these diagnostic taxa. …”
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Prevalence of suicide risk and comorbidities in postpartum women in Pelotas Prevalência do risco de suicídio e de comorbidades em mulheres pós-parto em Pelotas by Daniele Tavares, Luciana Quevedo, Karen Jansen, Luciano Souza, Ricardo Pinheiro, Ricardo Silva

“…CONCLUSION: Lower education levels and psychiatric disorders are associated with suicide risk. Bipolar disorder is the psychiatric disorder with the highest impact on suicide risk.…”
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Is There a Psychiatric Diagnosis in Chronic Ankle Instability Patients? by John R. Allen, Caroline P. Hoch, Daniel J. Scott MD, MBA, Christopher E. Gross MD

“…Methods: A retrospective review was conducted of 276 patients (280 ankles) treated between 2005 and 2021 at an academic medical center by one of three fellowship-trained foot and ankle orthopaedic surgeons, of which 56 underwent surgery and 130 had a concomitant psychiatric diagnosis (i.e., anxiety=111, depression=105, post-traumatic stress disorder [PTSD]=19, obsessive- compulsive disorder [OCD]=6, bipolar disorder [BPD]=5). Data collected included demographics, conservative treatment history, and patient-reported outcome measures (PROMs), such as Visual Analogue Scale (VAS), Brief Resiliency Scale (BRS), 12-Item Short-Form Survey (SF-12), Somatic Symptom Scale (SSS-8), Pain Catastrophizing Scale (PCS), Pain Disability Index (PDI), Foot and Ankle Outcome Score (FAOS), and Foot and Ankle Ability Measure (FAAM). …”
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Multivariate network meta-analysis of pharmacological interventions for the treatment of acute bipolar mania: a bayesian approach using lognormal prior distribution by P. K. Malo, B. Bhaskarapillai, M. Kesavan

“…Moreover, the Canadian Network for mood and Anxiety Treatments, and Royal Australian and New Zealand College of Psychiatrists guidelines also recommended these drugs as first-line medications for treating bipolar disorder. Disclosure of Interest None Declared…”
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Clinical characteristics of bipolar 1 disorder in relation to interleukin-6: a cross-sectional study among Egyptian patients by May Hassan, Rasha Elzehery, Youssef M. Mosaad, Maged Mostafa, Ibrahem H. Rashed Elkalla, Mohamed Elwasify

“…Abstract Background Strong evidence in the literature points to the role of pro-inflammatory cytokines in bipolar disorder (BD) pathophysiology. Interleukin-6 (IL-6) is a pro and anti-inflammatory cytokine that was repeatedly found higher in bipolar patients than in healthy controls. …”
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The impact of the OPRM1, OPRK1, DCC genes polymorphisms on the motivation for non-suicidal self-injury in young adults: a pilot study by A. A. Kibitov, G. E. Mazo

“…The majority of the sample had a diagnosis of bipolar disorder (78,6%; n=20). Characteristics and motivation for the NSSI were measured by the Inventory of Statements about Self-Injury (ISAS). …”
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Understanding Mental Health Issues in Different Subdomains of Social Networking Services: Computational Analysis of Text-Based Reddit Posts by Seoyun Kim, Junyeop Cha, Dongjae Kim, Eunil Park

“…ObjectiveIn this study, we analyzed the distinctive linguistic characteristics in users’ posts on specific mental disorder subreddits (depression, anxiety, bipolar disorder, borderline personality disorder, schizophrenia, autism, and mental health) and further validated their distinctiveness externally by comparing them with posts of subreddits not related to mental illness. …”
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Preferential Effects of Cariprazine on Counteracting the Disruption of Social Interaction and Decrease in Extracellular Dopamine Levels Induced by the Dopamine D3 Receptor Agonist,... by Jan Kehr, Jan Kehr, Fu-Hua Wang, Fumio Ichinose, Shimako Yoshitake, Shimako Yoshitake, Bence Farkas, Béla Kiss, Nika Adham

“…Cariprazine is a potent DA D3-preferring D3/D2 receptor partial agonist that is approved for the treatment of schizophrenia and bipolar disorder. The objective of the study was to compare the abilities of cariprazine, aripiprazole (another DA receptor partial agonist with more D2 receptor preference), and ABT-925 (a selective DA D3 antagonist) to counteract the social deficit and neurochemical alterations induced by the D3 receptor-preferring agonist (+)-PD 128907 (PD) in rats. …”
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2437 by Deepthi S. Varma, Jasmine Mack, Linda Cottler

“…Chronic health conditions such as hypertension (41.6% vs. 33.7%), diabetes (14% vs. 10.5%), and cancer (12.1% vs. 8.3%), and comorbid psychiatric symptoms such as anxiety (54.2% vs. 10.8%) and bipolar disorder (23.8% vs. 2.8%) were significantly higher (p<0.001) among women with depression compared with their counterparts. …”
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Drug Induced Bullous Lesion Caused By Valproic Acid in Bipolar Affective Disorder:A Case Report by H. D. Polat, D. Göverti

“…Objectives We wanted to draw attention that drug induced bullous lesions which has been seen rarely in the literature caused by valproic acid in bipolar disorder. Methods We examined the side effects of valproic acid in one of our patients with bipolar affective disorder using our observations and laboratory tests. …”
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Pilot Testing in the Wild: Feasibility, Acceptability, Usage Patterns, and Efficacy of an Integrated Web and Smartphone Platform for Bipolar II Disorder by Kathryn Fletcher, Katrina Lindblom, Elizabeth Seabrook, Fiona Foley, Greg Murray

“…Despite technical challenges with the prototype intervention (from user, hardware, and software standpoints), acceptability was adequate, and most participants rated the intervention positively in terms of concept (companion app with website: 19/25, 76%), content (19/25, 76%), and credibility and utility in supporting their management of bipolar disorder (17/25, 68%). Evaluation using behavioral archetypes identified important use pathways and a provisional model to inform platform refinement. …”
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