Clinical experiences with 6-monthly paliperidone palmitate beyond the diagnosis of schizophrenia. A retrospective study by S. Benavente López, S. Bolaño Mendoza, A. Parra González, A. Lara Fernández, A. Herencias Nevado, E. Baca García

“…Conclusions 6-monthly paliperidone palmitate may be an effective and well-tolerated treatment for the treatment of schizophrenia and other diagnoses such as bipolar disorder or borderline personality disorder. According to objective data, 6-monthly paliperidone palmitate could be an effective and well-tolerated treatment as an alternative to monthly and quarterly presentations of the same molecule. …”
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Effects of psychiatric disorders on Type A acute aortic dissection pathogenesis and analysis of follow-up results by Paolo Nardi, Antonio Pellegrino, Francesco Bianchi, Marco Russo, Guglielmo Saitto, Piero Caporali, Francesca D'Auria, Alberto Siracusano, Giovanni Ruvolo, Luigi Chiariello

“…Postoperatively, in 28 cases, a definitive diagnosis of PD (group PD) was made in agreement with the diagnostic and statistical manual of mental disorders-IV criteria, including: Major depression (n=13), anxious-depressive syndrome (n=6), bipolar disorder Type 2 (n=4), panic attacks (n=2), paranoid schizophrenia (n=1), and anxiety (n=2). 32 patients without a definitive psychiatric diagnosis were classified as Group non-PD. …”
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Prescription patterns of quetiapine for multiple drug abuse, depression, and psychosis: A retrospective study by Ayman M. Al-Qaaneh, Osama S. Al-Mohammadi, Razan A. Musharraf, Jumanah S. AlSaedi, Jana L. Shaker, Ahmed J. Aldhafiri

“…Background: Quetiapine is an atypical antipsychotic prescribed for schizophrenia, bipolar disorder, multiple drug abuse (MDA), generalized anxiety disorder, severe depression, dementia, and mood disorders. …”
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Blood homocysteine concentration and mood disorders with mixed features among patients with alcohol use disorder by Francesco Oliva, Maurizio Coppola, Raffaella Mondola, Daniele Ascheri, Francesco Cuniberti, Gabriele Nibbio, Rocco Luigi Picci

“…Previous studies have found a relationship between depressive symptoms severity and BHC in AUD patients and recently some authors have found high BHC among patients with bipolar disorder, both during manic and depressive episodes and in euthymic state. …”
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Evaluating increased resource use in fibromyalgia using electronic health records by Margolis JM, Masters ET, Cappelleri JC, Smith DM, Faulkner S

“…The chance of high resource use was significantly increased (P<0.001) 26% among African-Americans vs Caucasians and for patients with specific comorbid conditions ranging from 6% (musculoskeletal pain or depression/bipolar disorder) to 21% (congestive heart failure). Factors significantly associated with increased medications ordered included being female (P<0.001) and specific comorbid conditions (P<0.05). …”
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Mortality risk of antipsychotic augmentation for adult depression. by Tobias Gerhard, T Scott Stroup, Christoph U Correll, Soko Setoguchi, Brian L Strom, Cecilia Huang, Zhiqiang Tan, Stephen Crystal, Mark Olfson

“…Patients with alternative indications for antipsychotic medications, such as schizophrenia, psychotic depression, or bipolar disorder, were excluded.<h4>Exposure</h4>Augmentation treatment for depression with a newer antipsychotic or with a second antidepressant.…”
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HSPA12A controls cerebral lactate homeostasis to maintain hippocampal neurogenesis and mood stabilization by Jialing Wang, Ting Lu, Yali Gui, Xiaojin Zhang, Xiaofei Cao, Yuehua Li, Chuanfu Li, Li Liu, Zhengnian Ding

“…Abstract Mood instability, a subjective emotional state defined as rapid mood oscillations of up and down, is a symptom that occurs in several psychiatric disorders, particularly major depressive disorder and bipolar disorder. Heat shock protein A12A (HSPA12A) shows decreased expression in the brains of schizophrenia patients. …”
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Lithium plus valproate combination therapy versus monotherapy for relapse prevention in bipolar I disorder (BALANCE): a randomised open-label trial by Geddes, JR, Goodwin, GM, Rendell, J, Azorin, J-M, Cipriani, A, Ostacher, MJ, Alder, N, Morriss, R, Juszczak, E

“…<p><strong>Background</strong></p> Lithium carbonate and valproate semisodium are both recommended as monotherapy for prevention of relapse in bipolar disorder, but are not individually fully effective in many patients. …”

Impact of DISC1 variation on neuroanatomical and neurocognitive phenotypes by Carless, M, Glahn, D, Johnson, M, Curran, J, Bozaoglu, K, Dyer, T, Winkler, A, Cole, SA, Almasy, L, MacCluer, J, Duggirala, R, Moses, E, Göring, H, Blangero, J

“…Although disrupted in schizophrenia 1 (<em>DISC1</em>) has been implicated in many psychiatric disorders, including schizophrenia, bipolar disorder, schizoaffective disorder and major depression, its biological role in these disorders is unclear. …”

Differential effect on myelination through abolition of activity dependent synaptic vesicle release or reduction of overall electrical activity of selected cortical projections in... by Korrell, K, Disser, J, Parley, K, Vadisiute, A, Requena-Komura, M, Fodder, H, Pollart, C, Knott, G, Molnar, Z, Hoerder-Suabedissen, A

“…As myelination is central for brain development and plasticity, and deficits are implicated in several neural disorders such as multiple sclerosis, major depressive disorder, bipolar disorder and schizophrenia, it is important to elucidate the underlying mechanisms regulating myelination. …”

Investigations of the potential schizophrenia susceptibility gene Kinase Interacting with Stathmin (KIS) by Bristow, G

“…</p><p>KIS protein and mRNA was quantified in two large human post-mortem brain series to determine if KIS expression is altered in schizophrenia or bipolar disorder, or in relation to the leading schizophrenia-associated SNP (rs7513662). …”

Patient outcomes following discharge from secure hospitals by Fiminska, Z

“…Schizophrenia increased the risk of readmission. Bipolar disorder (HR=1.461, 95% CI=1.196-1.785, p&amp;LT;.000 and personality disorder (HR=1.496, 95% CI=1.345-1.663, p&amp;LT;.000) were associated with increased risk of violent offending.…”

Patterns of stressful life events and polygenic scores for five mental disorders and neuroticism among adults with depression by Crouse, JJ, Park, SH, Byrne, EM, Mitchell, BL, Scott, J, Medland, SE, Lin, T, Wray, NR, Martin, NG, Hickie, IB

“…In the Australian Genetics of Depression Study (N = 14,146; 75% female), we tested whether polygenic scores (PGS) for major depression, bipolar disorder, schizophrenia, anxiety, ADHD, and neuroticism were associated with reported exposure to 32 childhood, past-year, lifetime, and accumulated stressful life events (SLEs). …”

Identifying predictors of suicide in severe mental illness: A feasibility study of a clinical prediction rule (Oxford Mental Illness and Suicide Tool or OxMIS) by Senior, M, Burghart, M, Yu, R, Kormilitzin, A, Liu, Q, Vaci, N, Nevado-Holgado, A, Pandit, S, Zlodre, J, Fazel, S

“…<p><strong>Background:</strong><br /> Oxford Mental Illness and Suicide tool (OxMIS) is a brief, scalable, freely available, structured risk assessment tool to assess suicide risk in patients with severe mental illness (schizophrenia-spectrum disorders or bipolar disorder). OxMIS requires further external validation, but a lack of large-scale cohorts with relevant variables makes this challenging. …”

Clinical insight into latent variables of psychiatric questionnaires for mood symptom self-assessment by Tsanas, A, Saunders, K, Bilderbeck, A, Palmius, N, Goodwin, G, De Vos, M

“…<br/><br/> Methods: We elicited responses from 131 participants: 48 bipolar disorder (BD), 32 borderline personality disorder (BPD), and 51 healthy controls (HC), collected longitudinally (median [interquartile range, IQR]: 363 [276] days). …”

Preexisting neuropsychiatric conditions and associated risk of severe COVID-19 infection and other acute respiratory infections by Ranger, T, Clift, AK, Patone, M, Coupland, C, Hatch, R, Thomas, K, Watkinson, P, Hippisley-Cox, J

“…<br><strong> Exposures </strong> Diagnosis of and/or medication for anxiety, mood, or psychotic disorders and diagnosis of dementia, depression, schizophrenia, or bipolar disorder. <br><strong> Main Outcomes and Measures </strong> COVID-19–related mortality, or hospital or intensive care unit admission; SARI-related mortality, or hospital or intensive care unit admission. …”

13th National Congress of the South African Society of Psychiatrists, 20-23 September 2004 by Eugene Allers, Christer Allgulander, Sean Exner Baumann, Charles L Bowden, P Buckley, David J Castle, Beatrix J Coetzee, Franco Colin, A M Dikobe, Charl Els, Robin Emsley, Senathi Fisha, A E Gangat, T Goba, Gerhard Grundling, Jürgen Harms, S M Hawkridge, Erick Hollander, M L Janet, A B R Janse van Rensburg, Shabeer Ahmed Jeeva, J A Joska, Andre Joubert, Sean Z Kaliski, V N Khanyile, Fred Kigozi, B Levinson, Marilyn Lucas, E N Madela-Mntla, M Y H Moosa, Piet Oosthuizen, Ted Parran, A Pauw, Willie Pienaar, Felix Potocnik, Ramovha Rachel, J. L Roos, Steven P Roose, Martin Scholtz, Soraya Seedat, M Spitzer, Dan J Stein, Ugash Subramaney, Dave Swingler, Christopher Paul Szabo, Godfrey B Tangwa, Michael Trimble, H van der Bijl, L M van der Merwe, Vasi van Deventer, C W van Staden, W J C Verbeeck, G C Verster, Merryll Vorster, Bruce Lydiard

“…Long term maintenance treatment of Bipolar Disorder: Preventing relapse Charles L. Bowden 7. …”
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Immune-Related Genetic Overlap Between Regional Gray Matter Reductions and Psychiatric Symptoms in Adolescents, and Gene-Set Validation in a Translational Model by Lukas Penninck, El Chérif Ibrahim, Eric Artiges, Eric Artiges, Victor Gorgievski, Sylvane Desrivières, Severine Farley, Irina Filippi, Carlos E. A. de Macedo, Raoul Belzeaux, Raoul Belzeaux, Tobias Banaschewski, Arun L. W. Bokde, Erin Burke Quinlan, Herta Flor, Herta Flor, Antoine Grigis, Hugh Garavan, Penny Gowland, Andreas Heinz, Rüdiger Brühl, Frauke Nees, Frauke Nees, Frauke Nees, Dimitri Papadopoulos Orfanos, Tomáš Paus, Tomáš Paus, Luise Poustka, Juliane H. Fröhner, Michael N. Smolka, Henrik Walter, Robert Whelan, Julien Grenier, Gunter Schumann, Gunter Schumann, Gunter Schumann, Marie-Laure Paillère Martinot, Marie-Laure Paillère Martinot, Eleni T. Tzavara, Eleni T. Tzavara, Eleni T. Tzavara, Jean-Luc Martinot, for the IMAGEN Consortium

“…Adolescence is a period of vulnerability for the maturation of gray matter (GM) and also for the onset of psychiatric disorders such as major depressive disorder (MDD), bipolar disorder and schizophrenia. Chronic neuroinflammation is considered to play a role in the etiology of these illnesses. …”
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A two-arm, randomised feasibility trial using link workers to improve dental visiting in people with severe mental illness: a protocol paper by Claire Hilton, Abigail Morris, Girvan Burnside, Rebecca Harris, Vishal R. Aggarwal, Sarah Procter, Robert Griffiths, Paul French, Louise Laverty, Fiona Lobban, Katherine Berry, David Shiers, Rebecca Golby, Fanni Fazekas, Kyriakos Valemis, Antonia Perry, Connie Newens, Eirian Kerry, Pauline Mupinga, Efstathia Gkioni, Christopher Lodge, Alison Dawber, Emma Elliott, Farah Lunat, Jasper Palmier-Claus

“…Abstract Background People with severe mental illness (e.g. psychosis, bipolar disorder) experience poor oral health compared to the general population as shown by more decayed, missing and filled teeth and a higher prevalence of periodontal disease. …”
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Mental pain and depressive symptoms in the determination of suicidal ideation among psychiatric patients by E. Rogante, S. Sarubbi, D. Erbuto, M. A. Trocchia, S. P. Iancau, F. Manfreda, F. Splendori, M. Tinè, A. V. Vallerga, L. Longhini, I. Berardelli, M. Innamorati, M. Pompili

“…Results 32.5% of the patients had bipolar disorder, 21.4% had MDD, 24.8% had schizophrenia or other psychotic disorders, and 15% had a personality disorder. …”
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