Efficacy, Safety, and Retention Rate of Extended-Release Divalproex Versus Conventional Delayed-Release Divalproex: A Meta-Analysis of Controlled Clinical Trials by Chen Qi Zhang, Hong Yan Li, Yong Wan, Xue Yang Bai, Lu Gan, Juan Wang, Hong Bin Sun

“…According to our study, VPA-ER presented clinically significant benefits compared with the placebo in the population with bipolar disorder (BD) (39.5% versus 27.2%, p < 0.001). …”
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Health conditions in adults with HIV compared with the general population: A population-based cross-sectional analysis by Daniel R. Morales, David Moreno-Martos, Nashaba Matin, Patricia McGettigan

“…Meanwhile individual conditions that were more likely included: liver fibrosis, sclerosis, and cirrhosis (OR_3.23 [1.85–5.20]); pulmonary embolism (OR_2.06 [1.15–3.36]); male infertility (OR_2.23 [1.50–3.16]) and female infertility (OR_2.01 [1.34–2.88]); bipolar disorder (OR_2.93 [1.52–5.05]) and depression (OR_1.49 [1.28–1.71]); cervical malignancy (OR_4.64 [1.15–12.15]); and infections. …”
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Drugs and high hospitalization rate: are they related? by I. M. Figueiredo, I. Cargaleiro, M. Nascimento

“…Public Health Rep 2019; 134(1):17-26) that can be accidental or not. 24% to 32% of patients with Substance Induced Psychosis develop later a schizophrenia spectrum disorder or bipolar disorder (Starzer MSK et al. Am J Psychiatry 2018;175(4):343–350) leading to a chronic use of medication and, in several instances, to a necessity of psychiatric in-patient treatment with long hospital stays and high readmission rates (Khan S. …”
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LATE ONSET PSYCHOSIS AND VERY LATE ONSET PSYCHOSIS: WHAT ARE THE POSSIBLE ETHIOLOGIES? by A. C. Ramos, S. C. Martins, T. M. Afonso, N. B. Santos, P. Gonçalves, T. Maia

“…Primary causes of LOP and VLOP are schizophrenia (of late onset), schizophrenia-like very late onset psychosis, delusion disorder, unipolar depression with psychotic symptoms and bipolar disorder. Secondary causes should also be considered, such as delirium, dementia (Alzheimer’s, Lewi bodies and vascular), and substances abuse; even more rare, other conditions should be considered, as cerebrovascular accident, encephalitis, epilepsy, and multiple sclerosis. …”
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The development of an intersectoral intervention to patients with severe mental disease and selected somatic chronic diseases by Anne Marie Lyngsø, Dorte Høst, Michaela Schiøtz, Julie Grew

“…Patients aged ≥36 ≤ 65 years who appear in their individual general practitioner’s record system with schizophrenia, schizoaffective disorder or bipolar disorder are invited for screening for the selected somatic diseases. …”
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Staying at the crossroads: assessment of the potential of serum lithium monitoring in predicting an ideal lithium dose Em uma encruzilhada: potencial do nível plasmático de lítio c... by Thiago Zaqueu Lima, Miriam Marcela Blanco, Jair Guilherme dos Santos Júnior, Carolina Tesone Coelho, Luiz Eugênio Mello

“…OBJECTIVE: Lithium has been successfully employed to treat bipolar disorder for decades, and recently, was shown to attenuate the symptoms of other pathologies such as Alzheimer's disease, Down's syndrome, ischemic processes, and glutamate-mediated excitotoxicity. …”
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Digital Medicine System in Veterans With Severe Mental Illness: Feasibility and Acceptability Study by Sarah Gonzales, Olaoluwa O Okusaga, J Corey Reuteman-Fowler, Megan M Oakes, Jamie N Brown, Scott Moore, Allison A Lewinski, Cristin Rodriguez, Norma Moncayo, Valerie A Smith, Shauna Malone, Justine List, Raymond Y Cho, Amy S Jeffreys, Hayden B Bosworth

“…MethodsThis open-label, 2-site, provider-randomized trial assessed aripiprazole refill adherence in Veterans with schizophrenia, schizoaffective disorder, bipolar disorder, or major depressive disorder. We randomized 26 providers such that their patients either received TAU or DMS for a period of 90 days. …”
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Family Talk versus usual services in improving child and family psychosocial functioning in families with parental mental illness: a randomised controlled trial and cost analysis by Mairead Furlong, Colm McGuinness, Christine Marie Mulligan, Sharon Lisa McGarr, Sinead McGilloway

“…Parental disorders included anxiety/depression (57%), Bipolar Disorder (20%), Borderline Personality Disorder (12%), Post-Traumatic Stress Disorder (8%) and psychosis (2%). …”
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Assessing patients’ acceptance of their medication to reveal unmet needs: results from a large multi-diseases study using a patient online community by Jérémy Lambert, Michael Chekroun, Hélène Gilet, Catherine Acquadro, Benoit Arnould

“…Mean ACCEPT© Acceptance/General score for those 19 diseases were 61.2 (SD = 31.9) for type 1 diabetes, 59.8 (SD = 32.3) for asthma, 56.3 (SD = 34.3) for hypertension, 52.0 (SD = 32.2) for chronic obstructive pulmonary disease, 51.7 (SD = 27.0) for epilepsy, 50.1 (SD = 33.1) for bipolar disorder, 49.9 (SD = 33.1) for type 2 diabetes, 48.6 (SD = 31.6) for multiple sclerosis, 46.1 (SD = 34.5) for Crohn’s disease/ulcerative colitis, 44.3 (SD = 31.5) for depression, 42.8 (SD = 31.5) for lupus, 42.3 (SD = 33.0) for arthrosis, 41.8 (SD = 32.6) for Parkinson’s disease, 40.5 (SD = 32.2) for rheumatoid arthritis, 38.6 (SD = 31.7) for breast cancer, 36.4 (SD = 36.4) for myocardial infarction, 35.8 (SD = 32.0) for ankylosing spondylitis, 34.1 (SD = 32.3) for psoriasis, and 33.7 (SD = 31.7) for fibromyalgia. …”
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Modeling the neuropsychiatric manifestations of Lowe syndrome using induced pluripotent stem cells: defective F-actin polymerization and WAVE-1 expression in neuronal cells by Jesse Barnes, Franklin Salas, Ryan Mokhtari, Hedwig Dolstra, Erika Pedrosa, Herbert M. Lachman

“…Fortunately, the discovery of induced pluripotent stem (iPS) cells has provided an opportunity to grow patient-specific neurons, which can be used to model neurodevelopmental disorders in vitro, as demonstrated in the many studies that have been published in the past few years in autism spectrum disorders (ASD), schizophrenia (SZ), bipolar disorder (BD), and IDD. Methods We now report the first findings in neurons and neural progenitor cells (NPCs) generated from iPS cells derived from patients with LS and their typically developing male siblings, as well as an isogenic line in which the OCRL gene has been incapacitated by a null mutation generated using CRISPR-Cas9 gene editing. …”
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Digital Phenotyping for Differential Diagnosis of Major Depressive Episode: Narrative Review by Eric Ettore, Philipp Müller, Jonas Hinze, Matthias Riemenschneider, Michel Benoit, Bruno Giordana, Danilo Postin, Rene Hurlemann, Amandine Lecomte, Michel Musiol, Hali Lindsay, Philippe Robert, Alexandra König

“…It can be found in different pathologies such as major depressive disorder (MDD), bipolar disorder (BD), posttraumatic stress disorder (PTSD), or even occur in the context of psychological trauma. …”
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Valproate-induced severe symptomatic hyponatremia in a patient with schizoaffective disorder: a case study and literature review by K. Heflin, M. ElSayed

“…Sodium valproate (VPA), an antiepileptic indicated to treat bipolar disorder, blocks sodium (Na) and calcium ions. …”
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Organizational features of mental health facilities and adequacy of treatment. Multilevel analysis from the italian region lombardy by C. Conflitti, M. Monzio Compagnoni, A. Lora, G. Corrao

“…Results 72115 patients have been identified: 33974 (47.1%), 28407 (39.4%) and 9734 (13.5%) suffering from depressive, schizophrenic or bipolar disorder respectively; 45.4% of them (32773 patients) received a MAT. …”
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The Full Informational Spectral Analysis for Auditory Steady-State Responses in Human Brain Using the Combination of Canonical Correlation Analysis and Holo-Hilbert Spectral Analys... by Po-Lei Lee, Te-Min Lee, Wei-Keung Lee, Narisa Nan Chu, Yuri E. Shelepin, Hao-Teng Hsu, Hsiao-Huang Chang

“…Auditory steady-state response (ASSR) is a translational biomarker for several neurological and psychiatric disorders, such as hearing loss, schizophrenia, bipolar disorder, autism, etc. The ASSR is sinusoidal electroencephalography (EEG)/magnetoencephalography (MEG) responses induced by periodically presented auditory stimuli. …”
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The structure of affective fluctuations in a non-clinical sample by N. N. Osipova, L. M. Bardenstein, G. A. Aleshkina, E. V. Dmitrieva

“…We used the clinical and psychopathological method, the Mini-International Neuropsychiatric Interview (MINI), and screening methods, such as the diagnostic questionnaire for bipolar disorder (Hypomania Checklist-32 (HCL-32)), and Hamilton Depression Scale (HAMD-17).Results. …”
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Serum BICC1 levels are significantly different in various mood disorders by Chen S, Jiang H, Xu Z, Zhao J, Wang M, Lu Y, Li J, Sun F, Yuan Y

“…Therefore, the aim of this study is to evaluate the ability of serum BICC1 to discriminate between various mood disorders, including MDD and the manic and depressive phases of bipolar disorder, namely bipolar mania (BM) and bipolar depression (BD). …”
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Inference of differentially expressed genes using generalized linear mixed models in a pairwise fashion by Douglas Terra Machado, Otávio José Bernardes Brustolini, Yasmmin Côrtes Martins, Marco Antonio Grivet Mattoso Maia, Ana Tereza Ribeiro de Vasconcelos

“…This tool also detects new potential candidate DEGs in the transcriptome data of patients with bipolar disorder, presenting a promising tool to detect more relevant genes. …”
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Use of Insomnia Treatments and Discussions About Sleep with Health Professionals Among Australian Adults with Mental Health Conditions by Russell DI, Reynolds AC, Appleton SL, Adams RJ, Correia H, Bowman JA, Gill TK, Metse AP

“…A subset included participants (n = 624, age 18– 85y) who self-reported a diagnosis of depression, bipolar disorder, anxiety, panic disorder, or post-traumatic stress disorder. …”
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Religião e transtornos mentais em pacientes internados em um hospital geral universitário Religion and psychiatric disorders in patients admitted to a university general hospital by Rachel Esteves Soeiro, Elisabetta S. Colombo, Marianne H. F. Ferreira, Paula S. A. Guimarães, Neury J. Botega, Paulo Dalgalarrondo

“…Intensity of religiosity was moderately associated with overall prevalence of disorders, especially bipolar disorder. It is reasonable to conclude that extreme situations (very intense versus very limited religious participation) are related to this finding, associating both an exacerbated pursuit of religion and alienation from it with altered mental states.…”
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Compulsory Psychiatric Admissions in an Italian Urban Setting: Are They Actually Compliant to the Need for Treatment Criteria or Arranged for Dangerous Not Clinical Condition? by Francesco Oliva, Luca Ostacoli, Elisabetta Versino, Alberto Portigliatti Pomeri, Pier Maria Furlan, Sara Carletto, Rocco Luigi Picci

“…The most prevalent psychiatric disorders leading to CA were schizophrenia (729; 25.4%), brief psychotic disorder (627; 21.8%), bipolar disorder episode (396; 13.8%), delusional disorder (292; 10.2%), and personality disorder (237; 8.3%). …”
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