Non-synaptic Cell-Autonomous Mechanisms Underlie Neuronal Hyperactivity in a Genetic Model of PIK3CA-Driven Intractable Epilepsy by Achira Roy, Victor Z. Han, Victor Z. Han, Angela M. Bard, Devin T. Wehle, Devin T. Wehle, Stephen E. P. Smith, Stephen E. P. Smith, Jan-Marino Ramirez, Jan-Marino Ramirez, Jan-Marino Ramirez, Jan-Marino Ramirez, Franck Kalume, Franck Kalume, Franck Kalume, Kathleen J. Millen, Kathleen J. Millen

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Hydroxychloroquine synergizes with the PI3K inhibitor BKM120 to exhibit antitumor efficacy independent of autophagy by Xin Peng, Shaolu Zhang, Wenhui Jiao, Zhenxing Zhong, Yuqi Yang, Francois X. Claret, Moshe Elkabets, Feng Wang, Ran Wang, Yuxu Zhong, Zhe-Sheng Chen, Dexin Kong

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Mouse models of human PIK3CA-related brain overgrowth have acutely treatable epilepsy by Achira Roy, Jonathan Skibo, Franck Kalume, Jing Ni, Sherri Rankin, Yiling Lu, William B Dobyns, Gordon B Mills, Jean J Zhao, Suzanne J Baker, Kathleen J Millen

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Phase 2 study of buparlisib (BKM120), a pan-class I PI3K inhibitor, in patients with metastatic triple-negative breast cancer by Ana C. Garrido-Castro, Cristina Saura, Romualdo Barroso-Sousa, Hao Guo, Eva Ciruelos, Begoña Bermejo, Joaquin Gavilá, Violeta Serra, Aleix Prat, Laia Paré, Pamela Céliz, Patricia Villagrasa, Yisheng Li, Jennifer Savoie, Zhan Xu, Carlos L. Arteaga, Ian E. Krop, David B. Solit, Gordon B. Mills, Lewis C. Cantley, Eric P. Winer, Nancy U. Lin, Jordi Rodon

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Positive Effects of PI3K/Akt Signaling Inhibition on PTEN and P53 in Prevention of Acute Lymphoblastic Leukemia Tumor Cells by Elahe Naderali, Behnaz Valipour, Amir Afshin Khaki, Jafar Soleymani Rad, Alireza Alihemmati, Mohammad Rahmati, Hojjatollah Nozad Charoudeh

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Apoptin Overexpression Efficiently Amplified Cytotoxic Effects of PI3K Inhibition Using BKM120 in Lymphoblastic Leukemia Cell Lines by Ali Anjam-Najmedini, Rohollah Vahabpour, Ava Safaroghli-Azar, Alireza Kazemi, Parvaneh Movahhed, Majid Momeny, Davood Bashash

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ＰＩ３Ｋ抑制剂ＢＫＭ１２０ 体外抗结外鼻型ＮＫ／Ｔ细胞淋巴瘤的作用

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PI3K Abrogation Using Pan-PI3K Inhibitor BKM120 Gives Rise to a Significant Anticancer Effect on AML-Derived KG-1 Cells by Inducing Apoptosis and G2/M Arrest by Soroush Sadeghi, Shadi Esmaeili, Atieh Pourbagheri - Sigaroodi, Ava Safaroghli - Azar, Davood Bashash

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