Comparison of in vivo and in vitro preimplantation embryo development in OXYS and WAG rats by V. V. Kozhevnikova, T. N. Igonina, E. Yu.  Brusentsev, V. I. Mokrousova, E. A.  Kizilova, I. N. Rozhkova, V. A. Naprimerov, S. Ya. Amstislavsky

“…Thereafter the percentage of embryos at blastocyst stage and the cell numbers in these blastocysts were counted in the same manner as for the in vivo experiment. …”
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Attenuation of Oxidative Stress and Regulation of AKT Signaling by Vanillic Acid during Bovine Pre-Implantation Embryo Development by Marwa El-Sheikh, Ayman Mesalam, Myeong-Don Joo, Tabinda Sidrat, Ahmed Atef Mesalam, Il-Keun Kong

“…Additionally, the total numbers of cells and trophectoderm cells per blastocyst were higher in the VA-treated group compared to control (<i>p</i> < 0.05). …”
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#315 : Determination of Clinical Pregnancy and Live Birth Rates in Autologous Cycles for Women Between 40 and 46 Years Old by Lucy Owens, Tegan Ekanayake, Mark Green, Deirdre Zander-Fox, Beverley Vollenhoven

“…Results: CPR and LBR declined with increasing maternal age for both fresh and frozen single blastocyst ETs (Tables 1 and 2), with no live births for women who had eggs collected at 46 years old. …”
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Preclinical evaluation of a new cryopreservation container for a limited number of human spermatozoa by Kumiko NAKATA, Kaoru YOSHIDA, Naoki YAMASHITA

“…There were no differences in the sperm membrane, DNA integrity, or in the embryo development rates to the blastocyst stage among the different frozen groups. …”
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Oxidative Stress and Assisted Reproduction: A Comprehensive Review of Its Pathophysiological Role and Strategies for Optimizing Embryo Culture Environment by Ashok Agarwal, Israel Maldonado Rosas, Christina Anagnostopoulou, Rossella Cannarella, Florence Boitrelle, Lina Villar Munoz, Renata Finelli, Damayanthi Durairajanayagam, Ralf Henkel, Ramadan Saleh

“…Furthermore, we highlight strategies to ameliorate the impact of OS during the whole human embryo culture period, from gametes to blastocyst stage.…”
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NRF2 attenuation aggravates detrimental consequences of metabolic stress on cultured porcine parthenote embryos by Werner Giehl Glanzner, Leticia Rabello da Silva Sousa, Karina Gutierrez, Mariana Priotto de Macedo, Luke Currin, Felipe Perecin, Vilceu Bordignon

“…Attenuation of NRF2 mRNA significantly decreased development of parthenote embryos to the blastocyst stage. When NRF2-attenuated embryos were cultured in presence of 3.5 mM or 7 mM glucose, development to the blastocyst stage was dramatically decreased in comparison to the control group (15.9% vs. 27.8% for 3.5 mM glucose, and 5.4% vs. 25.3% for 7 mM glucose). …”
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Increased Systemic Antioxidant Power Ameliorates the Aging-Related Reduction in Oocyte Competence in Mice by Sydney L. Lane, Jason C. Parks, Jennifer E. Russ, Shaihla A. Khan, William B. Schoolcraft, Ye Yuan, Mandy G. Katz-Jaffe

“…Compared to young mice, aged mice had fewer oocytes and reduced blastocyst development (<i>p</i> < 0.0001); açaí did not affect the oocyte numbers, but improved blastocyst formation (<i>p</i> < 0.05). …”
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Cryobiological Characteristics of L-proline in Mammalian Oocyte Cryopreservation by Lu Zhang, Xu Xue, Jie Yan, Li-Ying Yan, Xiao-Hu Jin, Xiao-Hui Zhu, Zhi-Zhu He, Jing Liu, Rong Li, Jie Qiao

“…The survival rate, 5-methylcytosine (5-mC) expression, fertilization rate, two-cell rate, and blastocyst rate in vitro were assessed by immunofluorescence and in vitro fertilization. …”
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Overlapping functions of RBBP4 and RBBP7 in regulating cell proliferation and histone H3.3 deposition during mouse preimplantation development by Lieying Xiao, Yanna Dang, Bingjie Hu, Lei Luo, Panpan Zhao, Shaohua Wang, Kun Zhang

“…Interestingly, RBBP4/7 depletion leads to a dramatic increase in H3.3 and H3K27ac abundance during morula-to-blastocyst transition. ChIP-seq analysis in early embryos and embryonic stem cells reveals enrichment of H3.3 at the promoter regions of RBBP4/7 target genes. …”
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Embryonic, genetic and clinical outcomes of fresh versus vitrified oocyte: A retrospective cohort study by Phuong Thi Dao, Son Truong Dang, Thuan Duc Nguyen, Anh Van Pham, Anh Tuan Do, Nguyen Van Hanh

“…The outcomes included the rates of oocyte survival, cleavage embryo, blastocyst, ploidy status, pregnancy, biochemical pregnancy and clinical pregnancy. …”
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Endometrial stromal cells of women with recurrent miscarriage fail to discriminate between high- and low-quality human embryos. by Charlotte H E Weimar, Annemieke Kavelaars, Jan J Brosens, Birgit Gellersen, Johanna M T de Vreeden-Elbertse, Cobi J Heijnen, Nick S Macklon

“…Cell-free migration zones were created and the effect of the presence of a high-quality (day 5 blastocyst, n = 13), a low-quality (day 5 blastocyst with three pronuclei or underdeveloped embryo, n = 12) or AC-1M88 trophoblast cell line spheroid on H-ESC migratory activity was analyzed after 18 hours. …”
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The Relationship between Sperm Oxidative Stress Alterations and IVF/ICSI Outcomes: A Systematic Review from Nonhuman Mammals by Jordi Ribas-Maynou, Marc Yeste, Albert Salas-Huetos

“…After IVF treatments, 80% of studies observed a negative effect of sperm oxidative stress on fertilization rates, and 100% of studies observed a negative effect on blastocyst rates. After ICSI treatments, a positive relationship of sperm oxidative stress with fertilization rates (75% of studies) and with blastocyst rates (83% of studies) was found. …”
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MiR-124-3p negatively impacts embryo implantation via suppressing uterine receptivity formation and embryo development by Kezhen Yao, Quanmin Kang, Kai Chen, Biwei Shi, Xiaofen Jin

“…Abstract During embryo implantation, blastocyst interacts with the receptivity endometrium and the endometrial epithelium secretes nurturing fluid to support embryonic development. …”
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Brilliant Cresyl Blue Negative Oocytes Show a Reduced Competence for Embryo Development after In Vitro Fertilisation with Sperm Exposed to Oxidative Stress by Lilli Bittner-Schwerda, Carolina Herrera, Sarah Wyck, Eleni Malama, Christine Wrenzycki, Heinrich Bollwein

“…Total cell number and apoptotic index were analysed in D7 blastocysts. BCB-neg. oocytes showed lower cleavage rates and blastocyst rates than unstained oocytes after IVF with NOX S (<i>p</i> < 0.05). …”
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Antioxidants in Mouse Embryo Culture and Vitrification Media Maintain an In Vivo Like Gene Expression Profile by Thi T. TRUONG, Alexandra J. HARVEY, David K. GARDNER

“…Aim: To determine the effect of A3 in culture and vitrification media on mouse blastocyst, fetal and placental gene expression. Method: Embryo transfers were conducted on in vivo flushed blastocysts or blastocysts cultured or vitrified with and without A3. …”
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Competence Classification of Cumulus and Granulosa Cell Transcriptome in Embryos Matched by Morphology and Female Age. by Rehannah Borup, Lea Langhoff Thuesen, Claus Yding Andersen, Anders Nyboe-Andersen, Søren Ziebe, Ole Winther, Marie Louise Grøndahl

“…This suggests that the gene signature at least partly include genes that relates to competence in the developing blastocyst.…”
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High NaCl Concentrations in Water Are Associated with Developmental Abnormalities and Altered Gene Expression in Zebrafish by Denis A. Seli, Andrew Prendergast, Yagmur Ergun, Antariksh Tyagi, Hugh S. Taylor

“…This study examined how changes in salinity affect the survival and development of zebrafish from the two-cell to the blastocyst stage and from the blastocyst to the larval stage. …”
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MicroRNA-210 Regulates Endoplasmic Reticulum Stress and Apoptosis in Porcine Embryos by Muhammad Rosyid Ridlo, Eui Hyun Kim, Geon A. Kim

“…A miR-210-mimic significantly decreased the cleavage, blastocyst rate, TCN, and expression levels of <i>XBP1</i> compared with other groups (<i>p</i> < 0.05). …”
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Repeats as global DNA methylation marker in bovine preimplantation embryos by Wenwen Li, Ann Van Soom, Luc Peelman

“…Satellite I and L1_BT showed significant methylation reduction at the blastocyst stage, while BovB and ERV1-1-I_BT showed no difference. …”
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Assessment of developmental rate of mouse embryos yielded from in vitro fertilization of the oocyte with treatment of melatonin and vitamin C simultaneously by Shadan Navid, Zahra Saadatian, Ali Talebi

“…Conclusion We conclude that the presence of melatonin and vitamin C antioxidants simultaneously and exclusively in the IVF medium leads to a reduction in ROS and ,as a result, improves the growth of the embryo up to the blastocyst stage.…”
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