Amino Acid Transport and Metabolism Regulate Early Embryo Development: Species Differences, Clinical Significance, and Evolutionary Implications by Lon J. Van Winkle

“…Disturbances in leucine uptake via system B^0,+ in blastocysts appear to alter the subsequent development of embryos, fetuses, and placentae, with undesirable consequences for offspring. …”
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The physiological and pathological mechanisms of early embryonic development by Jian Mu, Zhou Zhou, Qing Sang, Lei Wang

“…The zygote undergoes several rounds of division to form a blastocyst, and during this process, the zygote undergoes the maternal-to-zygotic transition to gain control of embryonic development and makes two cell fate decisions to differentiate into an embryonic and two extra-embryonic lineages. …”
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Prolactin Relationship with Fertility and In Vitro Fertilization Outcomes—A Review of the Literature by Mirela E. Iancu, Alice I. Albu, Dragoș N. Albu

“…Although not all studies agree, the available evidence suggests that higher prolactin levels in follicular fluid are associated with increased oocytes competence, but also with positive effects on corpus luteum formation and survival, endometrial receptivity, blastocyst implantation potential and survival of low-motile sperm. …”
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β-nicotinamide mononucleotide rescues the quality of aged oocyte and improves subsequent embryo development in pigs. by Leyi Li, Qinghe Han, Yurong Chen, Meng Zhang, Luyao Wang, Xinglan An, Sheng Zhang, Yanhui Zhai, Xiangpeng Dai, Bo Tang, Ziyi Li, Guanghong Xie

“…Compared with untreated senescent oocytes, the blastocyst formation rate and pluripotent genes of senescent oocytes treated with NMN were significantly increased. …”
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Carryover effects of feeding bulls with an omega-3-enriched-diet-From spermatozoa to developed embryos. by Dorit Kalo, Dan Reches, Noam Netta, Alisa Komsky-Elbaz, Yoel Zeron, Uzi Moallem, Zvi Roth

“…This was associated with differential gene expression in the blastocysts. Overall, the omega-3-enriched food improved the spermatozoa characteristics; this was further expressed in the developing blastocysts, suggesting a carryover effect from the spermatozoa to the embryos.…”
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TBP dynamics during mouse oocyte meiotic maturation and early embryo development. by Shao-Chen Sun, Xu-Guang Wang, Xue-Shan Ma, Xian-Ju Huang, Juan Li, Hong-Lin Liu

“…During mouse embryo development, the exogenous TBP was removed from the chromosomes of M phase zygotes, but was found to express weakly at the M phase of 2-cell. Moreover, in the blastocyst TBP was also detected at the M phase chromosomes. …”
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Inflammation-Related Molecules at the Maternal–Fetal Interface during Pregnancy and in Pathologically Altered Endometrium by Wlodzimierz Sieg, Jolanta Kiewisz, Amira Podolak, Grzegorz Jakiel, Izabela Woclawek-Potocka, Jakub Lukaszuk, Krzysztof Lukaszuk

“…The blastocyst expresses paternally derived alloantigens and induces inflammation during implantation. …”
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The influence of paternal overweight on sperm chromatin integrity, fertilization rate and pregnancy outcome among males attending fertility clinic for IVF/ICSI treatment by Riffat Bibi, Sarwat Jahan, Tayyaba Afsar, Ali Almajwal, Mohammad Eid Hammadeh, Nawaf W. Alruwaili, Suhail Razak, Houda Amor

“…In the embryo, developmental stage number of the embryo in cleavage was higher in normal weight men, while day 3 (D3) embryos, percent good quality embryo D3, and blastocyst formation rate were compared able between the groups. …”
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Stable maternal proteins underlie distinct transcriptome, translatome, and proteome reprogramming during mouse oocyte-to-embryo transition by Hongmei Zhang, Shuyan Ji, Ke Zhang, Yuling Chen, Jia Ming, Feng Kong, Lijuan Wang, Shun Wang, Zhuoning Zou, Zhuqing Xiong, Kai Xu, Zili Lin, Bo Huang, Ling Liu, Qiang Fan, Suoqin Jin, Haiteng Deng, Wei Xie

“…FGO-originated proteins frequently persist to blastocyst while corresponding transcripts are already downregulated or decayed. …”
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Effect of Supplementation of Cryoprotectant Solution with Hydroxypropyl Cellulose for Vitrification of Bovine Oocytes by Min-Jee Park, Seung-Eun Lee, Jae-Wook Yoon, Hyo-Jin Park, So-Hee Kim, Seung-Hwan Oh, Do-Geon Lee, Da-Bin Pyeon, Eun-Young Kim, Se-Pill Park

“…The cleavage rate of the non-VT group was significantly higher, but the blastocyst development rate and total cell number per blastocyst did not significantly differ between the non-VT and 50 HPC groups. …”
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Secondary sex ratio in assisted reproduction: an analysis of 1 376 454 treatment cycles performed in the UK. by Supramaniam, PR, Mittal, M, Ohuma, EO, Lim, LN, McVeigh, E, Granne, I, Becker, CM

“…Furthermore, success rates through ART have improved since 1991, with an increased number of blastocyst stage embryo transfers.</p> <p><strong>Wider implications of the findings</strong> This is the largest study to date evaluating the impact of ART on SSR. …”

In Vitro Embryogenesis and Gastrulation Using Stem Cells in Mice and Humans by Seung Yeon Oh, Seung Bin Na, Yoo Kyung Kang, Jeong Tae Do

“…During early mammalian embryonic development, fertilized one-cell embryos develop into pre-implantation blastocysts and subsequently establish three germ layers through gastrulation during post-implantation development. …”
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A successful twin healthy live birth achieved from eggs with a rare perivitelline space abnormality: A case report by Daniele Ferri, Domenico Baldini, Giorgio Maria Baldini

“…Only 2 eggs could fertilize correctly and reach the blastocyst stage on day 6. The embryos were frozen and subsequently transferred as frozen embryo transfer following the next menstrual cycle. …”
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Biochemical profiling of the follicular environment to predict oocyte competence in cattle. by Nayara Ribeiro Kussano, Mauricio Machaim Franco, Margot Alves Nunes Dode

“…On D8, the samples were grouped according to embryo production into those that gave rise to blastocysts (EMB) and those that did not reach the blastocyst stage (NEMB). …”
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Capturing Transitional Pluripotency through Proline Metabolism by Gabriella Minchiotti, Cristina D’Aniello, Annalisa Fico, Dario De Cesare, Eduardo Jorge Patriarca

“…PiCs maintain several properties of naïve pluripotency (teratoma formation, blastocyst colonization and 3D gastruloid development) and acquire a few traits of primed cells (flat-shaped colony morphology, aerobic glycolysis metabolism and competence for primordial germ cell fate). …”
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Hormonal fluctuations during the estrous cycle modulate Heme Oxygenase-1 expression in the uterus by Maria Laura Zenclussen, Pablo Ariel Casalis, Federico eJensen, Katja eWoidacki, Ana Claudia Zenclussen

“…Our data suggest an important role for hormones in HO-1 regulation in uterus that has a significant impact in receptivity and later on blastocyst implantation.…”
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Pluripotent Stem Cells for Transgenesis in the Rabbit: A Utopia? by Worawalan Samruan, Nathalie Beaujean, Marielle Afanassieff

“…Naive and primed PSCs notably differ by their ability to colonize a host blastocyst to produce germline-competent chimeras; hence, naive PSCs are valuable for transgenesis, whereas primed PSCs are not. …”
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Potential Development of Vitrified Immature Human Oocytes: Influence of the Culture Medium and the Timing of Vitrification by Irene Peinado, Isabel Moya, Laura García-Valverde, Raquel Francés, Rosana Ribes, Patrocinio Polo, María José Gómez-Torres, Ana Monzó

“…Similar survival rates and development to blastocysts were observed in all the conditions studied.…”
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PGF2alpha induced differential expression of genes involved in turnover of extracellular matrix in rat decidual cells by Callegari Eduardo A, Ferguson-Gottschall Susan, Gibori Geula

“…Decidualization can be induced by either the implantation of the blastocyst or by artificial stimuli. The process of decidua formation or decidualization, is characterized by growth and differentiation of endometrial stromal cells. …”
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Successful Treatment of Testicular Failure Type IV Without Micro-Testicular Epididymal Sperm Extraction: A Case Report by Nahathai Paktinun, Chartchai Srisombut, Thidarat Kongwattanasin, Krit Pongpirul

“…Twelve mature oocytes were selected for intracytoplasmic sperm injection (ICSI) with the retrieved sperms, of which 8 oocytes were successfully fertilized but only two reached the early blastocyst stage; the first embryo transfer was not successful. …”
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