Embryo response to aneuploidy through self-correction mechanism: a literature review by Achmad Kemal Harzif, Azizah Fitriayu Andyra, Atikah Sayogo, Nafi’atul Ummah, Aisyah Retno Puspawardani, Putri Nurbaeti, Budi Wiweko

“…However, there are doubts about the reliability of preimplantation genetic testing for aneuploidy at the blastocyst stage, as it may lead to a high rate of false positives and the discarding of "good" embryos. …”
Get full text

ANÁLISIS EPIDEMIOLÓGICO Y CLÍNICO DEL EMBARAZO ECTÓPICO: HOSPITAL BASE DE LOS ÁNGELES by Ignacio Cabrera Samith, Iván Perales C, Germán Romero A

“…<br>Background: Ectopic pregnancy (EP) occurs when the developing blastocyst becomes implanted at a site other than the endometrium of the uterine cavity. …”
Get full text

Epigenetic impairments in development of parthenogenetic preimplantation mouse embryos by Ngan Thi Kim HO, Thuy Van Thi NGUYEN, Thuan Van NGUYEN, Hong-Thuy BUI

“…At the four-cell stage, methylation of histone H3 at arginine 26 (Me-H3-R26) increased at nascent RNA repression sites in fertilized embryos, while parthenotes recorded weaker signals throughout the nucleoplasm, suggesting differences in pluripotency of the ICM cells between the two types of embryos. Moreover, at the blastocyst stage, we observed that the acetylation level of histone H4 at lysine 12 (Ac-H4-K12) was significantly decreased in parthenogenetic ICM compared to that in its fertilized counterpart. …”
Get full text

A comparative study of the effects of two different treatment periods with estradiol in endometrial preparation on the pregnancy outcome of frozen embryos by Shmim Pilehvari, Mahnaz Yavangi, Laleh Salemi, Zahra Charaghi

“…In both groups, estradiol and progesterone levels were measured the day before progesterone onset and then the embryos were transferred in the morula or blastocyst stage. Data analysis was done using SPSS statistical software (version 26) and chi-square and t-test.  …”
Get full text

Phytoestrogens Present in Follicular Fluid and Urine Are Positively Associated with IVF Outcomes following Single Euploid Embryo Transfer by Roberto Gonzalez-Martin, Andrea Palomar, Alicia Quiñonero, Nuria Pellicer, Caroline Zuckerman, Christine Whitehead, Richard T. Scott, Francisco Dominguez

“…In this prospective cohort study, 60 women attending IVI-RMA New Jersey undergoing IVF with single frozen embryo transfer (SET/FET) of good-quality euploid blastocyst after PGT-A analysis were recruited. Concentrations of two phytoestrogens (daidzein and genistein) in follicular fluid (FF) and urine (U) were measured by UPLC–MSMS, both collected on vaginal oocyte retrieval day. …”
Get full text

A comparison of co-culture with oviductal epithelial cells and growth on porcine zygote medium (PZM) on porcine embryos development by Chalothon Amporn, Sarawut Duongmawong, Somchit Guntaprom, Wilasinee Srisanyong, Phalita Koonnadilokpot, Sirikanda Thanasuwan, Dechawut Bunyaluk, Juggrid Jugsumrit, Jakrit Yaeram

“…These results indicated that in vitro production of porcine embryos using a chemically defined medium significantly increased the percentage of >4-cells, >16-cells development, and the blastocyst stage.…”
Get full text

Mifepristone Directly Disrupts Mouse Embryonic Development in Terms of Cellular Proliferation and Maturation In Vitro by Yu-Ting Su, Jia-Shing Chen, Yi-Ru Tsai, Kuo-Chung Lan, Cheng-Chun Wu, Fu-Jen Huang

“…The presence of progesterone receptors (PRs) in blastocysts and post-implantation embryos was also evaluated. …”
Get full text

Insights into the Role of Telomeres in Human Embryological Parameters. Opinions Regarding IVF by George Anifandis, Maria Samara, Mara Simopoulou, Christina I. Messini, Katerina Chatzimeletiou, Eleni Thodou, Alexandros Daponte, Ioannis Georgiou

“…Nonetheless, the telomere length of the embryos during the cleavage stages seems to have a paternal origin, but the telomere length can be further extended by telomerase activity during the blastocyst stage. The latter has been proposed as a new molecular biomarker with strong predictive value regarding male infertility. …”
Get full text

The Cell-Surface Marker Sushi Containing Domain 2 Facilitates Establishment of Human Naive Pluripotent Stem Cells by Nicholas Bredenkamp, Giuliano Giuseppe Stirparo, Jennifer Nichols, Austin Smith, Ge Guo

“…SUSD2 transcripts are enriched in the pre-implantation epiblast of human blastocysts and immunostaining shows localization of SUSD2 to KLF17-positive epiblast cells. …”
Get full text

The role of TGF superfamily gene expression in the regulation of folliculogenesis and oogenesis in mammals: a review by H. Piotrowska, B. Kempisty, P. Sosinska, S. Ciesiolka, D. Bukowska, P. Antosik, M. Rybska, K.P. Brussow, M. Nowicki, M. Zabel

“…Proper oocyte development during folliculo- and oogenesis also plays a critical role in normal zygote and blastocyst formation, as well as implantation and the birth of healthy offspring. …”
Get full text

Oviduct Epithelial Cell-Derived Extracellular Vesicles Improve Porcine Trophoblast Outgrowth by Xun Fang, Bereket Molla Tanga, Seonggyu Bang, Chaerim Seo, Heyyoung Kim, Islam M. Saadeldin, Sanghoon Lee, Jongki Cho

“…We found that embryo development and blastocyst formation rate was significantly increased (14.3% ± 0.6% vs. 6.0% ± 0.6%) after OEC EVs treatment. …”
Get full text

Combined refinements to somatic cell nuclear transfer methods improve porcine embryo development by Thanh Quang DANG-NGUYEN, David WELLS, Seiki HARAGUCHI, Nguyen Thi MEN, Hiep Thi NGUYEN, Junko NOGUCHI, Hiroyuki KANEKO, Kazuhiro KIKUCHI

“…Our modified method yielded approximately three times greater blastocyst formation rates. Moreover, resulting blastocysts had roughly twice as many cells as compared to blastocysts produced by the conventional SCNT method. …”
Get full text

Dynamics of the Reproductive Changes and Acquisition of Oocyte Competence in Nelore (<i>Bos taurus</i> <i>indicus</i>) Calves during the Early and Intermediate Prepubertal Periods by Taynan Stonoga Kawamoto, João Henrique Moreira Viana, Thais Preisser Pontelo, Maurício Machaim Franco, Otávio Augusto Costa de Faria, Andrei Antonioni Guedes Fidelis, Luna Nascimento Vargas, Ricardo Alamino Figueiredo

“…The proportion of the blastocyst rate to the controls was lower in EPP than in IPP calves (43.7% vs. 78.7%, respectively). …”
Get full text

BDE-47 Induces Mitochondrial Dysfunction and Endoplasmic Reticulum Stress to Inhibit Early Porcine Embryonic Development by Rong-Ping Liu, Sheng-Yan He, Jing Wang, Xin-Qin Wang, Zhe-Long Jin, Hao Guo, Chao-Rui Wang, Yong-Nan Xu, Nam-Hyung Kim

“…Exposure to 100 μM BDE-47 decreased the blastocyst rate and mRNA level of pluripotency genes but increased the level of LC3 and the expression of autophagy-related genes. …”
Get full text

Dynamic Methylation Changes of DNA and H3K4 by RG108 Improve Epigenetic Reprogramming of Somatic Cell Nuclear Transfer Embryos in Pigs by Yanhui Zhai, Zhiren Zhang, Hao Yu, Li Su, Gang Yao, Xiaoling Ma, Qi Li, Xinglan An, Sheng Zhang, Ziyi Li

“…RG-SCNT embryos had significantly higher cleavage and blastocyst rates (69.3±1.4%, and 24.72±2.3%, respectively) than FF-SCNT embryos (60.1±2.4% and 18.38±1.9%, respectively). …”
Get full text

Effects of electromagnetic waves on oocyte maturation and embryonic development in pigs by Jia-Si CHEN, Li-Kuang TSAI, Ting-Yu YEH, Tzai-Shiuan LI, Cheng-Han LI, Zung-Hang WEI, Neng-Wen LO, Jyh-Cherng JU

“…No obvious differences in cytoskeletal distribution and total cell numbers of blastocysts were investigated in the four IF-EMF treatments compared to those in the control group. …”
Get full text

RNA-Seq Reveals the Underlying Molecular Mechanism of First Cleavage Time Affecting Porcine Embryo Development by Xinhui Song, Tiantian Li, Xin Xiong, Huiquan Shan, Tong Feng, Kuiqing Cui, Deshun Shi, Qingyou Liu, Zhipeng Li

“…In this study, the embryos generated by parthenogenetic activation (PA) or in vitro fertilization (IVF) were monitored and recorded every 2 h and divided into two groups (early cleavage or late cleavage) based on the cleavage rate and blastocyst formation data. RNA sequencing was used to analyze the gene expression pattern of the embryos. …”
Get full text

Functional heterogeneity of embryonic stem cells revealed through translational amplification of an early endodermal transcript. by Maurice A Canham, Alexei A Sharov, Minoru S H Ko, Joshua M Brickman

“…Taken together our data support a model in which ES cell culture has trapped a set of interconvertible cell states reminiscent of the early stages in blastocyst differentiation that may exist only transiently in the early embryo.…”
Get full text

Melatonin Rescues Dimethoate Exposure-Induced Meiotic and Developmental Defects of Porcine Oocytes by Qi Jiang, Xin Qi, Chi Ding, Xingyu Liu, Yuanyuan Lei, Siying Li, Zubing Cao

“…Parthenogenetically activated embryos derived from DT-exposed oocytes could not develop to the 2-cell and blastocyst stage. Furthermore, DT exposure led to a significant increase in the rates of misaligned chromosomes, disorganized spindles, and abnormal actin assembly. …”
Get full text

Sequential analysis of global gene expression profiles in immature and <it>in vitro </it>matured bovine oocytes: potential molecular markers of oocyte maturation by Mehta Jai P, McGettigan Paul, Al Naib Abdullah, Leal Cláudia LV, Lonergan Patrick, Carter Fiona, Mamo Solomon, Evans Alexander CO, Fair Trudee

“…<p>Abstract</p> <p>Background</p> <p>Without intensive selection, the majority of bovine oocytes submitted to <it>in vitro </it>embryo production (IVP) fail to develop to the blastocyst stage. This is attributed partly to their maturation status and competences. …”
Get full text