Oral Antioxidant Treatment of Men Significantly Improves the Reproductive Outcome of IVF Cycles by Paola Scaruffi, Emanuele Licata, Elena Maccarini, Claudia Massarotti, Francesca Bovis, Fausta Sozzi, Sara Stigliani, Alessandro Dal Lago, Ida Casciano, Rocco Rago, Paola Anserini

“…Embryological outcomes (fertilization, embryo quality, blastocyst development) were significantly higher in T90 than T0 cycles. …”
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Anticardiolipin and/or anti-β2-glycoprotein-I antibodies are associated with adverse IVF outcomes by Li Wu, Xuhui Fang, Fangting Lu, Yu Zhang, Yanshi Wang, Joanne Kwak-Kim, Joanne Kwak-Kim

“…Women with aPL had lower numbers of total and perfect/available embryos and lower rates of MII oocytes, blastocyst formation, perfect and available embryos, implantation, clinical pregnancy, and take-home baby. …”
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Semen parameters and male reproductive potential are not adversely affected after three or more months of recovery from COVID-19 disease by Sara Stigliani, Claudia Massarotti, Claudia Massarotti, Francesca Bovis, Elena Maccarini, Paola Anserini, Paola Scaruffi

“…Normal fertilization (65%), cleavage (99%) and blastocyst development (40%) rates in treatments performed after male infection were within the expected range of competencies. …”
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Embryo Condition Media Collected from Polycystic Ovary Syndrome Patients with Abdominal Obesity Can Increase The Decidualization Potential of Healthy Endometrial Stromal Cells by Zohreh Shalchian, Saba Taheri, Maryam Hafezi, Tahereh Madani, Nahid Nasiri, Poopak Eftekhari Yazdi

“…The embryosof four groups were single-cultured up to the blastocyst stage. Their ECM(45λ/well) were pooled and added to healthy ESCs monolayer culture media to investigate their effects on decidualizationpotential via gene (PRL, IGFBP1, IL1-β, HOXA10, IL-6 and TNF-α) and protein (PRL, IGFBP1, IL1-β)expression analysis and ESCs migration assay.Results: The morphological analysis, migration assay (P≤0.0321), protein (P≤0.0139) and gene expression analysisshowed PCOS with AO accounted for the highest gene (PRL, IGFBP1, IL1-β, HOXA10, IL-6, TNF-α) and proteinmarkers (PRL, IGFBP1, IL1-β) (P≤0.05). …”
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Association of paternal MTHFR polymorphisms (C677T) with clinical outcomes in ICSI treatment by Yangyang Wan, Wenjing Liu, Bo Xu, Xiaohua Jiang, Juan Hua, Juan Hua

“…In addition, we conducted a comparative analysis of embryonic development, pregnancy, and neonatal outcomes among these three groups.ResultsThe embryonic development (including normal fertilization rate (80.14% vs. 83.06% vs. 85.10%; p = 0.37), high-quality embryo rate (45.26% vs. 43.69% vs. 46.04%; p = 0.72), blastocyst formation rate (42.47% vs. 43.18% vs. 39.38%; p = 0.62), implantation rate (42.47% vs. 36.25% vs. 41.22%; p = 0.62), and clinical pregnancy rate (64.71% vs. 58.75% vs. 66.67%; p = 0.59) were not comparable among these three groups. …”
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Improved early development of porcine cloned embryos by treatment with quisinostat, a potent histone deacetylase inhibitor by Anukul TAWEECHAIPAISANKUL, Jun-Xue JIN, Sanghoon LEE, Geon A KIM, Yoon Ho SUH, Min Seok AHN, Se Jun PARK, Byeong You LEE, Byeong Chun LEE

“…SCNT embryos were cultured under various conditions, and we found that treatment with 100 nM JNJ for 24 h post activation could improve blastocyst formation rates compared to the control (P < 0.05). …”
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An IGF1-expressing endometrial stromal cell population is associated with human decidualization by Jia-Wei Shi, Zhen-Zhen Lai, Hui-Li Yang, Wen-Jie Zhou, Xiao-Ya Zhao, Feng Xie, Song-Ping Liu, Wei-Dong Chen, Tao Zhang, Jiang-Feng Ye, Xiang-Yu Zhou, Ming-Qing Li

“…Abstract Background Decidualization refers to the process of transformation of endometrial stromal fibroblast cells into specialized decidual stromal cells that provide a nutritive and immunoprivileged matrix essential for blastocyst implantation and placental development. Deficiencies in decidualization are associated with a variety of pregnancy disorders, including female infertility, recurrent implantation failure (RIF), and miscarriages. …”
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Peroxisome Proliferator-Activated Receptor Gamma Modulator Promotes Neonatal Mouse Primordial Follicle Activation In Vitro by Sook Young Yoon, Ran Kim, Hyunmee Jang, Dong Hyuk Shin, Jin Il Lee, Dongwon Seol, Dong Ryul Lee, Eun Mi Chang, Woo Sik Lee

“…After 1 month, cPA-pretreated, transplanted ovaries produced the highest numbers of oocytes and polar bodies, exhibited the most advanced embryonic development, and had the greatest blastocyst formation rate compared to the rosiglitazone- and GW9662-pretreated groups. …”
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Effect of sequential embryo transfer on in vitro fertilization and embryo transfer outcomes: a systematic review and meta-analysis by Wending Teng, Hong Xian, Fang Wang, Yicheng Wang, Xiangqian Meng, Xiaojian Zhang, Xudong Shan, Jiangying Yi

“…Furthermore, among the repeated implantation failure (RIF) cohort, sequential embryo transfer surpassed blastocyst-stage transfer, delivering a heightened chemical pregnancy rate (OR = 1.66, 95% CI = 1.19–2.53) and clinical pregnancy rate (OR = 1.65, 95% CI = 1.19–2.27).ConclusionOur meta-analysis indicates that sequential transfer may enhance clinical pregnancy rate in a small subgroup of well-selected women. …”
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Association between ambient air pollutants and birthweight of singletons following assisted reproductive technologies by Xiaoming Jiang, Jiali Cai, Xinli Wang, Lanlan Liu, Jianzhi Ren

“…For patients receiving single blastocyst transfer with exposures below the China standard of 20 μg/m3, an increase of 10 μg/m3 in SO2 was associated with a 61.52 (95% CI: 1.13–121.91) g increase in birthweight. …”
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Finding of the optimal preparation and timing of endometrium in frozen-thawed embryo transfer: a literature review of clinical evidence by Ya-Wen Hsueh, Chien-Chu Huang, Shuo-Wen Hung, Chia-Wei Chang, Hsi-Chen Hsu, Tung-Chuan Yang, Wu-Chou Lin, Shan-Yu Su, Hsun-Ming Chang

“…Emerging evidence suggests that the optimal timing for FET using warmed blastocyst transfer is the LH surge+6 day, hCG administration+7 day, and the progesterone administration+6 day in the true natural cycle, modified natural cycle, and AC protocol, respectively. …”
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Outcomes and cost analysis of single-embryo transfer versus double-embryo transfer by Ker Yi Wong, Heng Hao Tan, John Carson Allen, JKY Chan, Tat Xin Ee, Ka-Hee Chua, Shuling Liu, Jessie Wai Leng Phoon, Veronique Viardot-Foucault, Sadhana Nadarajah, Tse Yeun Tan

“…Background: Studies had compared single-embryo transfer to double-embryo transfer with cleavage stage embryos and found that while single-embryo transfer was less costly, it was also associated with a lower live birth rate than double-embryo transfer. A single blastocyst transfer has been shown to improve the live birth rate per cycle compared to single-embryo transfer at cleavage stage. …”
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A comprehensive and universal approach for embryo testing in patients with different genetic disorders by Shuo Zhang, Caixia Lei, Junping Wu, Min Xiao, Jing Zhou, Saijuan Zhu, Jing Fu, Daru Lu, Xiaoxi Sun, Congjian Xu

“…Disease‐causing genes and chromosomal rearrangements were detected by haplotypes located within the 2 Mb region covering the targeted genes or breakpoint regions. Results Twelve blastocysts were thawed, and then transferred into the uterus of female patients. …”
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MicroRNAs secreted by human preimplantation embryos and IVF outcome by Shintaro Kamijo, Toshio Hamatani, Hiroyuki Sasaki, Hiroki Suzuki, Akane Abe, Osamu Inoue, Maki Iwai, Seiji Ogawa, Kei Odawara, Kanako Tanaka, Mutsumi Mikashima, Masami Suzuki, Kenji Miyado, Ryo Matoba, Yasushi Odawara, Mamoru Tanaka

“…Design Analysis of microRNA profiles from spent culture medium of blastocysts with good morphology that did or did not result in pregnancy. …”
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Collection of oocytes from donors in the growth phase of follicular development can enhance the production of bovine embryos for cryopreservation by M. Machatkova, K. Hanzalova, J. Horakova, Z. Reckova, P. Hulinska

“…In relation to the developmental stage, the development and hatching rates were significantly higher (P ≤ 0.01) for D7 than D8 early blastocysts (75.0 vs 41.2% and 50.0 vs 5.9%, respectively) and for D7 than D8 advanced blastocysts, (73.7 vs 57.1 and 52.6 vs 28.6%, respectively). …”
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Intrauterine Infusion of Leukocyte-Poor Platelet-Rich Plasma Is an Effective Therapeutic Protocol for Patients with Recurrent Implantation Failure: A Retrospective Cohort Study by Yanna Ban, Xiaoliang Yang, Yan Xing, Wenjun Que, Zebo Yu, Wenwu Gui, Ying Chen, Xiru Liu

“…Results: The β-hCG-positive rate (57.8% vs. 38.9%, <i>p</i> = 0.041), CPR (45.3% vs. 24.5%, <i>p</i> = 0.022), and LBR per ET cycle (42.2% vs. 18.5%, <i>p</i> = 0.009) were higher in the PRP group than in the control group, and the three variables (62.5% vs. 41.2%, <i>p</i> = 0.040, 47.5% vs. 23.5%, <i>p</i> = 0.033, and 47.5% vs. 20.6%, <i>p</i> = 0.027) in the PRP group transferred with the <i>blastocyst-stage embryos</i> were also higher than those in the control group. …”
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Telomere Length in Pig Sperm Is Related to In Vitro Embryo Development Outcomes by Jordi Ribas-Maynou, Yentel Mateo-Otero, Marina Sanchez-Quijada, Sandra Recuero, Ariadna Delgado-Bermúdez, Marc Llavanera, Marc Yeste

“…Interestingly, this correlation was not found when percentages of early blastocysts/blastocysts (r_s = 0.410; 95% C.I. = (−0.200 to 0.791); <i>p</i> = 0.164) and of hatching/hatched blastocysts (r_s = 0.356; 95% C.I. = (− 0.260 to 0.766); <i>p</i> = 0.233) were considered. …”
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Chaetocin Improves Pig Cloning Efficiency by Enhancing Epigenetic Reprogramming and Autophagic Activity by Pil-Soo Jeong, Bo-Woong Sim, Soo-Hyun Park, Min Ju Kim, Hyo-Gu Kang, Tsevelmaa Nanjidsuren, Sanghoon Lee, Bong-Seok Song, Deog-Bon Koo, Sun-Uk Kim

“…Treatment with 0.5 nM chaetocin for 24 h after activation significantly increased the developmental competence of SCNT embryos in terms of the cleavage rate, blastocyst formation rate, hatching rate, cell number, expression of pluripotency-related genes, and cell survival rate. …”
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Association between mild stimulated IVF/M cycle and early embryo arrest in sub fertile women with/without PCOS by Nagwa Elshewy, Dongmei Ji, Zhiguo Zhang, Dawei Chen, Beili Chen, Rufeng Xue, Huan Wu, Jianye Wang, Ping Zhou, Yunxia Cao

“…Results Mildly stimulated IVF/M resulted in cumulative clinical pregnancy and implantation rates (40.2, 28.7% in the PCOS group vs. 41.9, 36% in the non-PCOS group), respectively. The blastocyst formation rates were comparable (28% vs. 28.2%) in PCOS and non-PCOS groups, respectively. …”
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Effect of Zinc and Nano Zinc on Developmental Competence of Buffalo Oocytes by Omaima M. Kandil, Kholoud A. Alhallag, Sherif M. Shawky, Ibrahim S. Abu-Alya, Sahar M. Kandeel, Esraa A. Ismail, Said I. Fathalla

“…The transferable embryos (blastocyst & morula) rates significantly raised (P˂0.05) in the zinc sulfate (17.28 & 19.87 %, respectively) and nano zinc oxide groups (21.23 &26.21%, respectively) when compared with TCM-199 group (11.19 &13.75 %, respectively). …”
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