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1441
High initial β-hCG predicts IVF outcomes accurately and precludes the need for repeated measurements
Published 2023-10-01“…Nonetheless, the abortion rate was significantly lower in the group with β-hCG above the cutoff values in fresh (141 mIU/mL) and frozen (354.5 mIU/mL) cleavage stage transfers (17.2% vs 44%, P < 0.001 and 18.5% vs 38%, P = 0.003, respectively). Blastocyst transfers resulted in higher median initial β-hCG compared to cleavage embryo transfers (937 vs 600 mIU/mL), and the initial β-hCG values from frozen cleavage embryos were higher compared to fresh cleavage embryos (600 vs 400 mIU/mL). …”
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1442
The role of endometrial thickness in predicting ectopic pregnancy after in vitro fertilization and the establishment of a prediction model
Published 2022-09-01“…Compared to cleavage stage transfer, blastocyst transfer can reduce the risk of ectopic pregnancy (aOR = 0.36, 95%CI: 0.26-0.50, P < 0.0001). …”
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1443
Decidual natural killer cells and trophoblast cells: cellular, humoral and molecular mechanisms of interaction
Published 2022-12-01“…In the uterus, NK cells are located closely to the cells of fetal origin, i.e., trophoblast cells, which differentiate from the outer layer of the invading blastocyst. The purpose of the review article was to analyze the literature data on the studies of the molecular interactions between NK cells and trophoblast cells, as well as potential means of regulating these interactions. …”
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1444
#270 : Single-Center Retrospective Cohort Analysis: Preimplantation Genetic Testing for Monogenic Disorders (PGT-M) for Monogenic Nephropathy
Published 2023-12-01“…Finally, 80 vitrified-thawed single blastocyst transfer cycles were performed. Live births occurred in 38 women, of which 37 transferred embryos with non-pathogenic genotypes. …”
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1445
IGF2 reduces meiotic defects in oocytes from obese mice and improves embryonic developmental competency
Published 2022-07-01“…Our data indicated supplementation of IGF2 in a culture medium improves the blastocyst formation: from 46% in the HFD group to 61% in the HFD + IGF2-treatment group (50 nM IGF2). …”
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1446
Clinical pregnancy rate for frozen embryo transfer with HRT: a randomized controlled pilot study comparing 1 week versus 2 weeks of oestradiol priming
Published 2023-07-01“…Both groups received single blastocyst stage embryos on the 6th day of vaginal P4 administration. …”
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1447
The follicular-phase depot GnRH agonist protocol results in a higher live birth rate without discernible differences in luteal function and child health versus the daily mid-luteal...
Published 2022-09-01“…After matching, the blastocyst formation rates, oestradiol (E2) value on Day hCG + 9, progesterone (P) value on Day hCG + 9, implantation rates, clinical pregnancy rates, and LBR were more favourable in the depot GnRH-a protocol than in the long GnRH-a protocol (P < 0.05). …”
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1448
Sperm DNA integrity does play a crucial role for embryo development after ICSI, notably when good-quality oocytes from young donors are used
Published 2022-12-01“…In the DD cohort, the percentage of sperm with high overall DNA damage correlated with fertilization rates (Rs = − 0.666; P < 0.001) and with the percentage of blastocysts per injected oocyte (Rs = − 0.414; P = 0.040). …”
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1449
Living birth following preimplantation genetic testing for monogenic disorders to prevent low-level germline mosaicism related Nicolaides–Baraitser syndrome
Published 2022-09-01“…Amniocentesis was performed at the 16th week of gestation by copy-number variation-sequencing, karyotyping, and Sanger sequencing.Results: Eight surviving embryos were biopsied during the blastocyst stage. Karyomapping and Sanger sequencing were applied to detect the euploidy and paternal mutation. …”
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1450
Galectin-1 Used in Assisted Reproduction—Embryo Safety and Toxicology Studies
Published 2023-01-01“…There was no damage to the in vitro bovine embryo growth when considering cleavage percentage (%CLE), blastocyst development (Bl, Bx, Bh, and B) at Days 7 and 8, or an amount of rHGAL-1 supplementation ≤20 µg·mL<sup>−1</sup>. …”
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1451
Species origin of exogenous transcription factors affects the activation of endogenous pluripotency markers and signaling pathways of porcine induced pluripotent stem cells
Published 2023-04-01“…RNA sequencing confirmed ppiPSCs had distinct global transcriptional profiling, upregulated Hippo, PI3K-Akt, MAPK and relevant pluripotency signaling pathways as porcine blastocyst inner cell mass and expressed PGC early related genes. …”
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1452
The effect of endometriosis on live birth rate and other reproductive outcomes in ART cycles: a cohort study
Published 2018“…Compared to women with unexplained subfertility, those with endometriosis had fewer oocytes retrieved [(10.54 (95% CI 10.13-0.95) and 9.15 (95% CI 8.69-9.6), respectively], lower blastocyst transfer [OR 0.24 (95% CI 0.12-0.5), P = 0.0001] and a significantly reduced implantation rate [OR 0.73 (0.58-0.92), P = 0.007]. …”
Journal article -
1453
Effects of hormonal and oocyte activation treatments on in vitro embryo development and interspecies hybridization of bovidar embryos following intracytoplasmic sperm injection
Published 2011“…It was also found that supplementation with 50 ng/ml ghrelin in maturation and culture media enhanced nuclear maturation and blastocyst formation rates, respectively. Although inclusion of 50 ng/ml ghrelin in the culture medium strikingly increased the population of inner cell mass (ICM), trophoectoderm (TE) and total cell number cells of bovine blastocysts, no significant difference was detected in ratio of ICM: total cell number per blastocysts between the different treatment groups compared to the control. …”
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1454
Simultaneous Inhibition of Histone Deacetylases and RNA Synthesis Enables Totipotency Reprogramming in Pig SCNT Embryos
Published 2022-11-01“…Our findings revealed that transcription can be inhibited for up to 40 h of development in porcine embryos, produced either by activation, fertilization or SCNT, without detrimentally affecting their capacity to form a blastocyst and their average number of cells at this developmental stage. …”
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1455
Factors Affecting the Efficiency of In Vitro Embryo Production in Prepubertal Mediterranean Water Buffalo
Published 2022-12-01“…The best pregnancy rates were achieved when transferring blastocysts, compared to compact morula or hatched blastocysts. …”
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1456
YY2 in Mouse Preimplantation Embryos and in Embryonic Stem Cells
Published 2021-05-01“…Although YY2 is expressed during preimplantation development, its presence appears dispensable for developmental progress in vitro until formation of the blastocyst. Attenuation of <i>Yy2</i> levels failed to alter either <i>Zscan4</i> levels in two-cell embryos or IAP and MERVL levels at later preimplantation stages. …”
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1457
Comparison of cumulative live birth rates between progestin-primed ovarian stimulation protocol and gonadotropin-releasing hormone antagonist protocol in different populations
Published 2023-04-01“…The results of response to ovarian stimulation were also investigated, including numbers of oocytes retrieved, MII oocytes, 2PN, blastocysts, good-quality blastocysts, and usable blastocysts after biopsy, as well as rates of oocyte yield, blastocyst formation, good-quality blastocysts, and moderate or severe OHSS. …”
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1458
Hyperbaric oxygen therapy: a possible choice for patients with resistant thin endometrium during frozen embryo transfer treatments
Published 2023-09-01“…The IPR was similar in patients who received cleavage-stage embryos (0.0% vs. 6.7%, P = 1.00), but significantly higher in patients in the HBOT group who received blastocysts (53.8% vs. 18.2%, P = 0.017). Conclusions A period of HBOT prior to endometrium transformation contributes to increased endometrial thickness and facilitates blastocyst implantation in patients with resistant thin endometrium during FET treatments. …”
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1459
TET Family Members Are Integral to Porcine Oocyte Maturation and Parthenogenetic Pre-Implantation Embryogenesis
Published 2023-08-01“…After Bobcat339 treatment, early parthenogenetic embryos exhibited abnormal 5mC and 5hmC levels, which resulted in compromised cleavage and blastocyst rate. The mRNA levels of EIF1A and DPPA2 (ZGA marker genes) were significantly decreased, which may explain why the embryos were arrested at the 4-cell stage after Bobcat339 treatment. …”
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1460
Inhibitory Effects of 3-Methylcholanthrene Exposure on Porcine Oocyte Maturation
Published 2023-03-01“…The rates of cleavage and blastocyst of embryos derived from 3-MC-exposed oocytes were significantly lower than those in the control group. …”
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