Thymic epithelial cell support of thymopoiesis does not require Klotho by Xing, Y, Smith, MJ, Goetz, CA, McElmurry, RT, Parker, SL, Dullei, M, Hollander, GA, Weinberg, KI, Tolar, J, Stefanski, HE, Blazar, BR

Despite high levels of expression in thymic epithelial cells, miR-181a1 and miR-181b1 are not required for thymic development. by Heather E Stefanski, Yan Xing, Patricia A Taylor, Stefano Maio, Jorge Henao-Meija, Adam Williams, Richard A Flavell, Georg A Hollander, Bruce R Blazar

Get full text

Bone marrow stromal and vascular smooth muscle cells have chemosensory capacity via bitter taste receptor expression. by Troy C Lund, Amanda J Kobs, Ashley Kramer, Mick Nyquist, Marcos T Kuroki, John Osborn, Diane S Lidke, Shalini T Low-Nam, Bruce R Blazar, Jakub Tolar

Get full text

Regulatory T Cells Condition Lymphatic Endothelia for Enhanced Transendothelial Migration by Wenji Piao, Yanbao Xiong, Lushen Li, Vikas Saxena, Kile D. Smith, Keli L. Hippen, Christina Paluskievicz, Marina Willsonshirkey, Bruce R. Blazar, Reza Abdi, Jonathan S. Bromberg

Get full text

Human CD19-specific switchable CAR T-cells are efficacious as constitutively active CAR T-cells but cause less morbidity in a mouse model of human CD19+ malignancy by Travis S Young, Mark J Osborn, Bruce R Blazar, Michael Jensen, Christopher A Pennell, Heather Campbell, Sophie Viaud, Meghan D Storlie, Sara Bolivar-Wagers, Yosef Refaeli

Get full text

Maintenance of CD4 T cell fitness through regulation of Foxo1 by Newton, R, Shrestha, S, Sullivan, J, Yates, K, Compeer, E, Ron-Harel, N, Blazar, B, Bensinger, S, Haining, W, Dustin, M, Campbell, D, Chi, H, Turka, L

Mechanisms by Which Obesity Promotes Acute Graft-Versus-Host Disease in Mice by Lam T. Khuat, Logan V. Vick, Eunju Choi, Cordelia Dunai, Alexander A. Merleev, Emanual Maverakis, Bruce R. Blazar, Arta M. Monjazeb, William J. Murphy, William J. Murphy

Get full text

Venetoclax imparts distinct cell death sensitivity and adaptivity patterns in T cells by Lindsey M. Ludwig, Katrina M. Hawley, David B. Banks, Anika T. Thomas-Toth, Bruce R. Blazar, Megan E. McNerney, Joel D. Leverson, James L. LaBelle

Get full text

CRISPR/Cas9-Based Lateral Flow and Fluorescence Diagnostics by Mark J. Osborn, Akshay Bhardwaj, Samuel P. Bingea, Friederike Knipping, Colby J. Feser, Christopher J. Lees, Daniel P. Collins, Clifford J. Steer, Bruce R. Blazar, Jakub Tolar

Get full text

Validated graft-specific biomarkers identify patients at risk for chronic graft-versus-host disease and death by Brent R. Logan, Denggang Fu, Alan Howard, Mingwei Fei, Jianqun Kou, Morgan R. Little, Djamilatou Adom, Fathima A. Mohamed, Bruce R. Blazar, Philip R. Gafken, Sophie Paczesny

Get full text

Differential phenotypes of memory CD4 and CD8 T cells in the spleen and peripheral tissues following immunostimulatory therapy by Gail D. Sckisel, Annie Mirsoian, Christine M. Minnar, Marka Crittenden, Brendan Curti, Jane Q. Chen, Bruce R. Blazar, Alexander D. Borowsky, Arta M. Monjazeb, William J. Murphy

Get full text

Selectivity matters: selective ROCK2 inhibitor ameliorates established liver fibrosis via targeting inflammation, fibrosis, and metabolism by Alexandra Zanin-Zhorov, Wei Chen, Julien Moretti, Melanie S. Nyuydzefe, Iris Zhorov, Rashmi Munshi, Malavika Ghosh, Cindy Serdjebi, Kelli MacDonald, Bruce R. Blazar, Melissa Palmer, Samuel D. Waksal

Get full text

Deletion of AMPK minimizes graft-versus-host disease through an early impact on effector donor T cells by Darlene A. Monlish, Kevin J. Beezhold, Pailin Chiaranunt, Katelyn Paz, Nathan J. Moore, Andrea K. Dobbs, Rebecca A. Brown, John A. Ozolek, Bruce R. Blazar, Craig A. Byersdorfer

Get full text

Effective Multi-lineage Engraftment in a Mouse Model of Fanconi Anemia Using Non-genotoxic Antibody-Based Conditioning by Meera A. Srikanthan, Olivier Humbert, Kevin G. Haworth, Christina Ironside, Yogendra S. Rajawat, Bruce R. Blazar, Rahul Palchaudhuri, Anthony E. Boitano, Michael P. Cooke, David T. Scadden, Hans-Peter Kiem

Get full text

Embryonic pig pancreatic tissue transplantation for the treatment of diabetes. by Smadar Eventov-Friedman, Dalit Tchorsh, Helena Katchman, Elias Shezen, Anna Aronovich, Gil Hecht, Benjamin Dekel, Gideon Rechavi, Bruce R Blazar, Ilan Feine, Orna Tal, Enrique Freud, Yair Reisner

Get full text

P63 targeted deletion under the FOXN1 promoter disrupts pre-and post-natal thymus development, function and maintenance as well as induces severe hair loss by Heather E. Stefanski, Yan Xing, Jemma Nicholls, Leslie Jonart, Emily Goren, Patricia A. Taylor, Alea A. Mills, Megan Riddle, John McGrath, Jakub Tolar, Georg A. Hollander, Bruce R. Blazar

Get full text

P63 targeted deletion under the FOXN1 promoter disrupts pre-and post-natal thymus development, function and maintenance as well as induces severe hair loss. by Heather E Stefanski, Yan Xing, Jemma Nicholls, Leslie Jonart, Emily Goren, Patricia A Taylor, Alea A Mills, Megan Riddle, John McGrath, Jakub Tolar, Georg A Hollander, Bruce R Blazar

Get full text

T cell progenitor therapy–facilitated thymopoiesis depends upon thymic input and continued thymic microenvironment interaction by Smith, M, Reichenbach, D, Parker, S, Riddle, M, Mitchell, J, Osum, K, Mohtashami, M, Stefanski, H, Fife, B, Bhandoola, A, Hogquist, K, Holländer, G, Zúñiga-Pflücker, J, Tolar, J, Blazar, B

The lineage stability and suppressive program of regulatory T cells require protein O-GlcNAcylation by Bing Liu, Oscar C. Salgado, Sangya Singh, Keli L. Hippen, Jason C. Maynard, Alma L. Burlingame, Lauren E. Ball, Bruce R. Blazar, Michael A. Farrar, Kristin A. Hogquist, Hai-Bin Ruan

Get full text

MicroRNAs control the maintenance of thymic epithelia and their competence for T lineage commitment and thymocyte selection. by Zuklys, S, Mayer, C, Zhanybekova, S, Stefanski, H, Nusspaumer, G, Gill, J, Barthlott, T, Chappaz, S, Nitta, T, Dooley, J, Nogales-Cadenas, R, Takahama, Y, Finke, D, Liston, A, Blazar, B, Pascual-Montano, A, Holländer, G