Identification and characterisation of the haematopoietic stem/progenitor cells at risk for leukaemia development following radiation exposure by Verbiest, T

“…We report here, for the first time, that allogeneic haematopoietic stem cells can compete for niches in the nonmyeloablated NSG bone marrow compartment and that the nonmyeloablated NSG bone marrow microenvironment is capable of supporting allogeneic long-term HSC engraftment and differentiation. …”

The structural, mechanical, and biological variation of silica bioglasses obtained by different sintering temperatures by Sarmast Sh, M., Dayang Radiah, A. B., Hoey, D. A., Abdullah, N.

“…These findings highlight the potential of fine-tuning the sintering temperature to modulate the crystallinity of bioglasses, thereby enhancing their application scope in bone tissue engineering.…”

Current trends in additive manufacturing of selective laser melting for biomedical implant applications by Nazari, Aufa Adlia, Hassan, Mohamad Zaki, Ismail, Zarini, Ramlie, Faizir, Jamaludin, Khairur Rijal, Md. Daud, Mohd. Yusof, Ren, James

“…The rate of degradation and corrosion resistance of the metallic SLM implant, which would have an impact on cell proliferation and bone remodeling between the surrounding tissue, were discussed. …”
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Microfluidic Platform for Investigating Prostate Cancer Metastasis by Ng, Wei Kai

“…Objective: To develop a microfluidic model of bone metastasis. [1st Award]-[Peer Assessment Review]…”
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The development and application of fish scale waste for tissue engineering applications : waste-to-resource conversion of resource resilient materials by Wang, Jun Kit

“…Moreover, fish scales also consist of hydroxyapatite (HA), which is the main component of bone with excellent osteoconductive properties to promote bone regeneration. …”
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Key transcriptional regulators of neutrophil function in inflammation by Ai, Z

“…Neutrophils undergo tightly controlled genomic and transcriptional changes while transitioning between bone marrow, blood, and tissue sites. However, the molecular mechanisms underlining neutrophil function during inflammation have yet to be fully elucidated. …”

Thermal spraying of bioceramic (Hydroxyapatite) coatings by Kweh, Sidney Wei Kheong.

“…Hydroxyapatite (HA) is one such biomaterial which possesses unique biocompatibility that can promote osteogenesis or new bone formation. Thermal spray processes like plasma spraying are widely used to coat metallic implants with HA which proved to be highly effective. …”
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Simulation methods and tissue property models for non-invasive transcranial focused ultrasound surgery by Connor, Christopher W

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Transcriptional regulation of type I interferon responses of myeloid antigen presenting cells by Sin, Wei Xiang

“…Here we show IRF7 also regulates IFN-β responses to bacterial lipopolysaccharide in bone marrow-derived macrophages (BMDMs) but not in bone marrow-derived dendritic cells (BMDCs). …”
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Comparison of a simplified skin pointer device compared with a skeletal marker for knee rotation laxity : a cadaveric study using a rotation-meter by Puah, Ken Lee, Yew, Andy Khye Soon, Chou, Siaw Meng, Lie, Denny Tijauw Tjoen

“…One Kirscher wire was driven into the tibial tubercle as a bone marker and a skin pointer was attached. Rotational forces of 3, 6 and 9 nm applied at 0°, 30°, 45°, 60° and 90° of knee flexion were analysed using the Pearson correlation coefficient and paired t-test. …”
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Struvite precipitation for the recovery of ammonium nitrogen from landfill leachate by Mohamad S. J. Darwish

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Application of MCG-PTCC system on neo-cartilage regeneration by Jiang, Yuwei

“…This project aims to apply the advance fabricated micro-cavities gel (MCG) construct and the innovative phase transfer cell culture (PTCC) strategy to cartilage tissue engineering to realize the self-formation of the bone fide neo-cartilage tissue. The phenomenon called edge flourish (EF) is the underlying principle for successfully creating the MCG-PTCC system. …”
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Segmentation of liver tumor from CT images by La, Cam Chung

“…Finally, a new semi-automatic method is proposed to improve liver tumor segmentation by finding out the ribcage curves on every CT slice, using the rib bone traces. One can use the rib curve as a post-processing step to fine tune the segmentation.…”
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Functional analysis of a hypomorphic allele shows that MMP14 catalytic activity is the prime determinant of the Winchester syndrome phenotype by de Vos, Ivo J. H. M., Goggi, Julian L., Wilson, Gabrielle R., Stegmann, Alexander P. A., Amor, David J., Dunn, Norris Ray, Carney, Thomas James, Lockhart, Paul J., Coull, Barry J., van Steensel, Maurice A. M., Tao, Evelyn Yaqiong, Ong, Sheena Li Ming, Scerri, Thomas, Low, Chernis Guai Mun, Wong, Arnette Shi Wei, Grussu, Dominic, van Geel, Michel, Janssen, Renske, Bahlo, Melanie

“…Notably, the zebrafish model will be a valuable tool for developing novel therapeutic approaches to a devastating bone disorder.…”
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First clinical experience following the consensus guide for calibrating a proton stopping power ratio curve in a new proton centre by Koh, Calvin Wei Yang, Lew, Kah Seng, Wibawa, Andrew, Master, Zubin, Yeap, Ping Lin, Chua, Clifford Ghee Ann, Lee, James Cheow Lei, Tan, Hong Qi, Park, Sung Yong

“…Results: The results show a WET difference of less than 3.5% except for the result in the Bone region between Schneider's and ESTRO's methods. …”
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Development of image-based method for the quantitative assessment of cartilage damage from CT as a biomarker in osteoarthritis by Zheng, J-Q

“…In OA, cartilage damage and subchondral bone deformations are critical indicators. Therefore, this thesis introduces and validates two innovative frameworks for automated OA assessment, centering on the image analysis of cartilages and subchondral bones.…”

Improving detection of chromosomal abnormalities in multiple myeloma using fluorescence in situ hybridization by Naw, Wah Wah

“…D13S319/LAMP1 and IGH@/MAF, interphase FISH probes for del13q14 and t(14;16)(q32;q23) respectively, are used in this study to detect multiple myeloma cells in bone marrow aspirate of 20 patients. While CC could not detect del13q14 and t(14;16)(q32;q23) in any of the 20 patients, interphase FISH detected these chromosomal abnormalities in half (10/20) of the patients. …”
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Automated detection and segmentation of vertebral bodies in volumetric abdominal magnetic resonance images by Lin, Dehui.

“…Detection and segmentation of the column of vertebral bodies are intermediate steps required to identify the bone marrow which is considered as the wrongly labeled visceral adipose tissue in the assessment of abdominal obesity. …”
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Optimization of culture conditions in HS5 stroma suppported hematopoietic culture. by Goh, Carlye Qian Ling.

“…Stroma cells play an essential role in the bone marrow niche, the environment where hematopoietic cells and progenitors self-renew and differentiate into multiple lineage. …”
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Microfluidics based cell-cell interaction model by Bak Thavatchalam, Subhashree

“…In this study such a microfuidic chip has been developed whereby the bone marrow stromal cells have been cultured within the chip in a 3D microenvironment. …”
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