Kinematic analysis of an upper extremity stroke rehabilitation orthosis by Yang, Fang

“…This method also has some deficiencies, due to lack of the actual hand anatomy data for Singapore’s stroke patient, especially the joint angle of each finger bone, some assumptions and estimations are made. …”
Get full text

Morphological multiparameter filtration and persistent homology in mitochondrial image analysis by Chung, Yu-Min, Hu, Chuan-Shen, Sun, Emily, Tseng, Henry C.

“…Mutations in the autophagy gene Optineurin (OPTN) are associated with primary open-angle glaucoma (POAG), amyotrophic lateral sclerosis (ALS), and Paget's disease of the bone, but the pathophysiological mechanism is unclear. …”
Get full text

Development of bioactive PCL films using low temperature solvent free method by Lim, Lynette Sihui

“…In conclusion, based on the evaluation of the results, 10% MgCl2 has the potential to be developed as a bone scaffold.…”
Get full text

Molecular genetics of Dupuytren’s contracture by Aissvarya, Shankar, Ling, King-Hwa, Arumugam, Manohar, Thilakavathy, Karuppiah

Get full text

Mechanism of damnacanthal induced apoptosis in CEM-SS cell line by Gopalsamy, Banulata, Saiful Yazan, Latifah, Abdul Hamid, Hisyam

“…Leukaemia, is cancer of organs that is responsible to produce blood specifically the lymphatic system and bone marrow. Due to the harsh effects of currently used cancer drugs, damnacanthal, an anthraquinone obtained from the roots of Morinda elliptica is tested as a potential anticancer agent. …”
Get full text

Fracture energy and mechanical properties of toughened epoxy resin with eggshell powder by Fong, Collin, Sugiman, Sugiman, Chin, Desmond, Ahmad, Hilton

“…The material properties and fracture energy of toughened epoxy with eggshell powder (TEEP) were measured and investigated. Dog-bone specimens were fabricated to investigate the mechanical properties of TEEP (i.e. elastic modulus, Poisson’s ratios and tensile strength) and tested under quasi-static tensile loading. …”
Get full text

BMPR1A promotes ID2–ZEB1 interaction to suppress excessive endothelial to mesenchymal transition by Lee, Heon-Woo, Adachi, Takaomi, Pak, Boryeong, Park, Saejeong, Hu, Xiaoyue, Choi, Woosoung, Kowalski, Piotr S, Chang, C Hong, Clapham, Katharine R, Lee, Aram, Papangeli, Irinna, Kim, Jongmin, Han, Orjin, Park, Jihwan, Anderson, Daniel G, Simons, Michael, Jin, Suk-Won, Chun, Hyung J

“…Components of bone morphogenetic protein (BMP) signalling have been implicated in both pathogenesis of pulmonary arterial hypertension (PAH) and endothelial-mesenchymal transition (EndoMT). …”
Get full text

Telomere biology disorders by Kam, Michelle L. W., Nguyen, Trang T. T., Ngeow, Joanne Yuen Yie

“…Telomeres are DNA-protein structures at chromosome ends that maintain chromosome stability; their length affects cell replicative potential and senescence. A constellation of bone marrow failure, pulmonary fibrosis, liver cirrhosis and premature greying is suggestive, however incomplete penetrance results in highly variable manifestations, with idiopathic pulmonary fibrosis as the most common presentation. …”
Get full text

On-demand tailoring between brittle and ductile of poly(methyl methacrylate) (PMMA) via high temperature stretching by Wang, Changchun, Pek, Jia Xi, Chen, Hong Mei, Huang, Wei Min

“…Dog-bone shaped poly(methyl methacrylate) (PMMA) samples were pre-stretched at different temperatures (within the glass transition range and slightly above) to different strains. …”
Get full text

Finite element analysis of shoulder rotator cuff by Lee, Kenneth Jun Rui.

“…Material properties and connections between the tendons and the bone have been defined using the ANSYS software. …”
Get full text

Effectiveness of supervised versus self-directed rehabilitation for adults aged 50 years and over with ankle fractures: protocol for the AFTER trial by Keene, DJ, Achten, J, Forde, C, Png, ME, Grant, R, Draper, K, Appelbe, D, Tutton, E, Peckham, N, Dutton, SJ, Lamb, SE, Costa, ML

Prevalence of complications in older adults after hip fracture surgery: a systematic review and meta-analysis by Goh, EL, Khatri, A, Costa, A, Ting, A, Steiner, K, Png, ME, Metcalfe, D, Cook, J, Costa, M

Global availability of medications and health technologies for kidney care: A multinational study from the ISN-GKHA by Kelly, DM, Jones, ESW, Barday, Z, Arruebo, S, Caskey, FJ, Damster, S, Donner, J, Jha, V, Levin, A, Nangaku, M, Saad, S, Tonelli, M, Ye, F, Okpechi, IG, Bello, AK, Johnson, DW

“…There was reduced capacity for the management of CKD mineral bone disease in low-income countries (LICs) - serum parathyroid hormone was available in only 26% (n = 5) of LICs and the ability to administer non-calcium-based phosphate binders and cinacalcet was also very limited in LICs [16% (n = 3) and 5% (n = 1), respectively]. …”

An implantable piezoelectric ultrasound stimulator (ImPULS) for deep brain activation by Hou, Jason F, Nayeem, Md Osman Goni, Caplan, Kian A, Ruesch, Evan A, Caban-Murillo, Albit, Criado-Hidalgo, Ernesto, Ornellas, Sarah B, Williams, Brandon, Pearce, Ayeilla A, Dagdeviren, Huseyin E, Surets, Michelle, White, John A, Shapiro, Mikhail G, Wang, Fan, Ramirez, Steve, Dagdeviren, Canan

“…Ultrasound can aid in energy propagation, but transcranial ultrasound stimulation in the deep brain has limited spatial resolution caused by bone and tissue scattering. Here, we report an implantable piezoelectric ultrasound stimulator (ImPULS) that generates an ultrasonic focal pressure of 100 kPa to modulate the activity of neurons. …”
Get full text

Microglia and CD206⁺ border-associated mouse macrophages maintain their embryonic origin during Alzheimer's disease by Wu, Xiaoting, Saito, Takashi, Saido, Takaomi C., Barron, Anna M., Ruedl, Christiane

“…We used a novel inducible AD mouse model to investigate the contribution of bone marrow (BM) cells to the pool of fetal-derived brain macrophages during the development of AD. …”
Get full text

Musculoskeletal regeneration: a zebrafish perspective by Kaliya-Perumal, Arun-Kumar, Ingham, Philip William

“…Upon muscle injury, quiescent stem cells - known as satellite cells - become activated, proliferate, differentiate and fuse to form new myofibres, while bone fracture results in a phased response involving hematoma formation, inflammation, fibrocartilaginous callus formation, bony callus formation and remodelling. …”
Get full text

Capturing the fantastic voyage of monocytes through time and space by Teh, Ye Chean, Ding, Jeak Ling, Ng, Lai Guan, Chong, Shu Zhen

“…After birth, monocytes arise from bone marrow (BM)-derived HSCs and are released into the circulation upon their maturation, where they survey peripheral tissues and maintain endothelial integrity. …”
Get full text
Get full text

Chemical analysis of silica doped hydroxyapatite biomaterials consolidated by a spark plasma sintering method by Xu, Jinling, Khor, Khiam Aik

“…HA was prepared with 0, 1, 3 and 5 wt% silica, which are comparable to the measured silicon content of natural bone. After spray drying into micron sized powders, the silica doped HA (SiHA) powders were consolidated at 1000 C with a dwell time of 3 min using a spark plasma sintering (SPS) technique. …”
Get full text
Get full text

Electrospun nanofibers of collagen and chitosan for tissue engineering and drug delivery applications: A review by Ramakrishnan, Praveen, Ramprasath, Ramakrishnan, Jalaludeen, Abdulkadhar Mohamed, R., Jayakumar, Gimbun, Jolius, Balu, Ranganathan, S.B., Mohamed, T.M., Sridhar, Gunasekaran, Sivagaami Sundari, Davoodbasha, MubarakAli, Thajuddin, Nooruddin, Gnanasekaran, Lalitha, Sundaram, Thanigaivel

“…Studies concerning the medical applications of these nanofibers, such as wound healing, skin regeneration, bone tissue engineering, and neural repair, were also reviewed. …”
Get full text
Get full text

Evaluating the effect of rapamycin treatment in Alzheimer’s disease and aging using in vivo imaging: the ERAP phase IIa clinical study protocol by Svensson, Jonas E., Bolin, Martin, Thor, Daniel, Williams, Pete A., Brautaset, Rune, Carlsson, Marcus, Sörensson, Peder, Marlevi, David, Spin-Neto, Rubens, Probst, Monika, Hagman, Göran, Morén, Anton Forsberg, Kivipelto, Miia, Plavén-Sigray, Pontus

“…As exploratory outcomes, the study will assess change in multiple age-related pathological processes, such as periodontal inflammation, retinal degeneration, bone mineral density loss, atherosclerosis and decreased cardiac function. …”
Get full text