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101
Transcriptional regulation of type I interferon responses of myeloid antigen presenting cells
Published 2016“…Here we show IRF7 also regulates IFN-β responses to bacterial lipopolysaccharide in bone marrow-derived macrophages (BMDMs) but not in bone marrow-derived dendritic cells (BMDCs). …”
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Thesis -
102
First clinical experience following the consensus guide for calibrating a proton stopping power ratio curve in a new proton centre
Published 2024“…Results: The results show a WET difference of less than 3.5% except for the result in the Bone region between Schneider's and ESTRO's methods. …”
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Journal Article -
103
Application of MCG-PTCC system on neo-cartilage regeneration
Published 2009“…This project aims to apply the advance fabricated micro-cavities gel (MCG) construct and the innovative phase transfer cell culture (PTCC) strategy to cartilage tissue engineering to realize the self-formation of the bone fide neo-cartilage tissue. The phenomenon called edge flourish (EF) is the underlying principle for successfully creating the MCG-PTCC system. …”
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Final Year Project (FYP) -
104
Developing hydroxyapatite CAPS coatings on metallic implants for tissue replacement
Published 2008“…Hydroxyapatite (HA) is an appropriate ceramic for artificial teeth or bones due to its excellent biocompatibility and bioactivity. …”
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Thesis -
105
Comparison of a simplified skin pointer device compared with a skeletal marker for knee rotation laxity : a cadaveric study using a rotation-meter
Published 2019“…One Kirscher wire was driven into the tibial tubercle as a bone marker and a skin pointer was attached. Rotational forces of 3, 6 and 9 nm applied at 0°, 30°, 45°, 60° and 90° of knee flexion were analysed using the Pearson correlation coefficient and paired t-test. …”
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Journal Article -
106
BMPR1A promotes ID2–ZEB1 interaction to suppress excessive endothelial to mesenchymal transition
Published 2024“…Components of bone morphogenetic protein (BMP) signalling have been implicated in both pathogenesis of pulmonary arterial hypertension (PAH) and endothelial-mesenchymal transition (EndoMT). …”
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Article -
107
Segmentation of liver tumor from CT images
Published 2013“…Finally, a new semi-automatic method is proposed to improve liver tumor segmentation by finding out the ribcage curves on every CT slice, using the rib bone traces. One can use the rib curve as a post-processing step to fine tune the segmentation.…”
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Final Year Project (FYP) -
108
Telomere biology disorders
Published 2021“…Telomeres are DNA-protein structures at chromosome ends that maintain chromosome stability; their length affects cell replicative potential and senescence. A constellation of bone marrow failure, pulmonary fibrosis, liver cirrhosis and premature greying is suggestive, however incomplete penetrance results in highly variable manifestations, with idiopathic pulmonary fibrosis as the most common presentation. …”
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Journal Article -
109
Biocompatible materials for orbital wall reconstruction - an overview
Published 2022“…The reconstruction materials can be divided into autografts (bone or cartilage tissue) or allografts (metals, ceramics, or plastic materials, and combinations of these materials). …”
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Journal Article -
110
Improving detection of chromosomal abnormalities in multiple myeloma using fluorescence in situ hybridization
Published 2010“…D13S319/LAMP1 and IGH@/MAF, interphase FISH probes for del13q14 and t(14;16)(q32;q23) respectively, are used in this study to detect multiple myeloma cells in bone marrow aspirate of 20 patients. While CC could not detect del13q14 and t(14;16)(q32;q23) in any of the 20 patients, interphase FISH detected these chromosomal abnormalities in half (10/20) of the patients. …”
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Final Year Project (FYP) -
111
Automated detection and segmentation of vertebral bodies in volumetric abdominal magnetic resonance images
Published 2012“…Detection and segmentation of the column of vertebral bodies are intermediate steps required to identify the bone marrow which is considered as the wrongly labeled visceral adipose tissue in the assessment of abdominal obesity. …”
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Final Year Project (FYP) -
112
Optimization of culture conditions in HS5 stroma suppported hematopoietic culture.
Published 2013“…Stroma cells play an essential role in the bone marrow niche, the environment where hematopoietic cells and progenitors self-renew and differentiate into multiple lineage. …”
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Final Year Project (FYP) -
113
Microfluidics based cell-cell interaction model
Published 2014“…In this study such a microfuidic chip has been developed whereby the bone marrow stromal cells have been cultured within the chip in a 3D microenvironment. …”
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Thesis -
114
Activated invariant NKT cells regulate osteoclast development and function
Published 2011“…Because these same progenitors give rise to osteoclasts (OCs), which also mediate the egress of hematopoietic progenitors and orchestrate bone remodeling, we hypothesized that iNKT cells would extend their myeloid cell regulatory role to the development and function of OCs. …”
Journal article -
115
Recent advancements in additively manufactured hip implant design using topology optimization technique
Published 2025“…The recent advancement of additive manufacturing (AM) offers many benefits for the medical sector, which is revolutionizing modern bone repair surgery for patients, including those with damaged hip joints. …”
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Article -
116
Mortality and probability: philosophical considerations in selected contemporary British and Irish literature
Published 2022“…In analysing four texts by four authors - David Mitchell’s Ghostwritten, Ali Smith’s Artful, Mike McCormack’s Solar Bones, and Matt Haig’s The Midnight Library, this thesis seeks to portray that death can be reworked as a compassionate and comforting thought instead of the conventionally bleak end of existence. …”
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Thesis-Master by Research -
117
Structural insights into human brachyury DNA recognition and discovery of progressible binders for cancer therapy
Published 2025“…Brachyury is a transcription factor that plays an essential role in tumour growth of the rare bone cancer chordoma and is implicated in other solid tumours. …”
Journal article -
118
Tropism of subgroup J avian leukosis virus as detected by in situ hybridization
Published 1999“…Viral gene expression could not be detected in the bone marrow or tumour tissues using this test. Higher levels of viral gene expression in the bursa of Fabricius infected with RAV-1, but not with HPRS-103, might help explain the inability of the latter virus to induce lymphoid leukosis.…”
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Article -
119
Wear behaviour of NiTi shape memory alloys
Published 2016“…For example, since mechanical properties of NiTi SMAs are close to those of cortical bones, NiTi SMA based implants such as joint replacements, bone plates, and spine fracture fixations were developed. …”
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Thesis -
120
Emerging roles of downstream of kinase 3 in cell signaling
Published 2020“…In this review, we will focus on the structure and expression profile of Dok-3 and highlight its role during signal transduction in B cells, innate cells as well as in bone and lung tissues.…”
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Journal Article